期刊
CLINICAL MICROBIOLOGY AND INFECTION
卷 20, 期 7, 页码 O418-O420出版社
WILEY-BLACKWELL
DOI: 10.1111/1469-0691.12441
关键词
Dormancy; Mycobacterium tuberculosis; resuscitation promoting factors; sputum; treatment
资金
- Task Applied Science, Cape Town
We investigated the effect of Mycobacterium tuberculosis culture supernatant added to sputum cultures collected during the first 8 weeks of anti-tuberculosis treatment. With ongoing treatment duration, time to culture positivity decreased significantly in supernatant-enriched cultures, possibly due to stimulation of dormant or slowly metabolizing M. tuberculosis cells.
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