期刊
CLINICAL MICROBIOLOGY AND INFECTION
卷 18, 期 5, 页码 E144-E148出版社
ELSEVIER SCI LTD
DOI: 10.1111/j.1469-0691.2012.03796.x
关键词
Carbapenemase; gram-negative; NDM-1; OXA-181; OXA-48
资金
- European Community [241742]
Twenty-two carbapenem-resistant enterobacterial isolates were recovered from patients hospitalized between October 2010 and March 2011 at the Royal Hospital of Muscat, Sultanate of Oman. Eleven NDM-1, five OXA-48 and one NDM-1 plus OXA-181 producers of diverse ST types were recovered from clinical samples. All carbapenemase genes were located on self-conjugative plasmids and were nearly always associated with other resistance determinants, including extended-spectrum beta-lactamases and the ArmA methylase encoding resistance to aminoglycosides. This work highlights the dissemination of NDM-1 and OXA-48-type producers in the Middle East.
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