期刊
CLINICAL MICROBIOLOGY AND INFECTION
卷 18, 期 7, 页码 E254-E258出版社
WILEY-BLACKWELL
DOI: 10.1111/j.1469-0691.2012.03886.x
关键词
Genomic analysis; ICE; Klebsiella pneumoniae; NDM-1; optical map
资金
- Public Health Service from National Institutes of Health [2R15AI047115]
- US Department of Energy Joint Genome Institute through the Office of Science of the US Department of Energy [DE-AC02-05CH11231]
- Veterans Affairs Merit Review Program
- Geriatric Research Education and Clinical Center [VISN 10]
- PIP from CONICET [11420100100152]
- National Institutes of Health [RO1 AI063517-01]
Clin Microbiol Infect 2012; 18: E254E258 Abstract Comparison of genome-wide, high-resolution restriction maps of Klebsiella pneumoniae clinical isolates, including an NDM-1 producer, and in silico-generated restriction maps of sequenced genomes revealed a highly heterogeneous region we designated the high heterogeneity zone (HHZ). The HHZ consists of several regions, including a hot spot prone to insertions and other rearrangements. The HHZ is a characteristic genomic area that can be used in the identification and tracking of outbreak-causing strains.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据
分享论文
