期刊
CLINICAL MICROBIOLOGY AND INFECTION
卷 17, 期 8, 页码 1279-1282出版社
ELSEVIER SCI LTD
DOI: 10.1111/j.1469-0691.2011.03518.x
关键词
bla(CTX-M-15); Escherichia coli; ST131; Tanzania
资金
- WBUCHS
- Faculty of Medicine of the Justus-Liebig University Giessen
- Bundesministerium fuer Bildung und Forschung (BMBF, Germany) within the framework of the RESET research network [01KI1013G]
The molecular epidemiology of 32 non-duplicate, CTX-M-15 extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli strains, isolated from clinical samples, was investigated. Multilocus sequence typing revealed multiple sequence type clonal complexes: ST131 (12), ST405 (4), ST638 (3), ST38 (2), ST827 (2), ST224 (1), ST648 (1), ST46 (1) and two new sequence type clonal complexes (1845 and 1848) in 22 pulsed field gel electrophoresis clusters. The bla(CTX-M-15) gene was located on conjugative IncF plasmids. This is the first report of the worldwide emerging clonal complex ST131 linked to bla(CTX-M-15) in Tanzania and demonstrates the need for constant surveillance in developing countries to prevent the spread of these multiresistant isolates.
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