Review
Cardiac & Cardiovascular Systems
Yvonne Alexander, Elena Osto, Arno Schmidt-Trucksass, Michael Shechter, Danijela Trifunovic, Dirk J. Duncker, Victor Aboyans, Magnus Back, Lina Badimon, Francesco Cosentino, Marco De Carlo, Maria Dorobantu, David G. Harrison, Tomasz J. Guzik, Imo Hoefer, Paul D. Morris, Giuseppe D. Norata, Rosa Suades, Stefano Taddei, Gemma Vilahur, Johannes Waltenberger, Christian Weber, Fiona Wilkinson, Marie-Luce Bochaton-Piallat, Paul C. Evans
Summary: Endothelial cells play a crucial role in cardiovascular health, and dysfunction can be caused by cardiovascular risk factors but restored once stimuli are removed. There are various methods to measure endothelial function, with each having its pros and cons. It is recommended to adopt a consensus methodology like flow-mediated dilatation and establish reference values for different populations. Future studies should explore the integration of endothelial function measurements with patient-specific epigenetic data and other biomarkers.
CARDIOVASCULAR RESEARCH
(2021)
Article
Gastroenterology & Hepatology
S. Raj J. Trikha, Dustin M. Lee, Kayl E. Ecton, Scott D. Wrigley, Allegra R. Vazquez, Nicole S. Litwin, Keely N. Thomas, Yuren Wei, Micah L. Battson, Sarah A. Johnson, Kristine A. Kuhn, Sean P. Colgan, Christopher L. Gentile, Tiffany L. Weir
Summary: Transplanting fecal material from obese and lean individuals into germ-free mice led to significant alterations in vascular function in the mice, indicating that the gut microbiota associated with obesity can impact the vascular phenotype in the absence of weight or dietary differences. This suggests a potential role for microbiota-targeted therapies in preventing or treating cardiovascular disease.
Review
Medicine, General & Internal
D. van Lier, M. Kox, P. Pickkers
Summary: The article discusses the roles of DPP3 and ADM in the pathophysiology of sepsis and septic shock, as well as their associations with organ dysfunction and adverse outcomes. Research has shown that these two molecules represent distinct pathways involved in the development of septic shock.
JOURNAL OF INTERNAL MEDICINE
(2021)
Review
Nutrition & Dietetics
Yongbo She, Rabban Mangat, Sue Tsai, Spencer D. Proctor, Caroline Richard
Summary: Obesity is strongly linked to inflammation, impaired insulin signaling, lipid metabolism, and immune function. Recent research has provided insights into the mechanisms of immune dysfunction in obesity, using various animal and clinical models. Nutritional strategies, particularly those involving choline-rich foods, are emerging as potential ways to improve immune function in the context of obesity.
FRONTIERS IN NUTRITION
(2022)
Review
Nutrition & Dietetics
Maria Wobith, Arved Weimann
Summary: Patients undergoing gastrointestinal surgery are following enhanced recovery after surgery (ERAS) protocols, where oral feeding is emphasized and malnutrition is common. It is important to identify patients at metabolic risk early and monitor their nutritional status postoperatively, especially after surgery in the upper gastrointestinal tract. The article provides an overview of perioperative enteral nutrition concepts in these patients.
Review
Nutrition & Dietetics
Giulio Verna, Annamaria Sila, Marina Liso, Mauro Mastronardi, Marcello Chieppa, Hellas Cena, Pietro Campiglia
Summary: Iron deficiency affects people of all ages globally, particularly IBD patients, women, and children. Current therapies can restore normal levels but may have side effects, leading to a growing interest in innovative nutritional supplements and iron-rich superfoods.
Article
Endocrinology & Metabolism
Martine Paquette, Sophie Bernard, Alexis Baass
Summary: This study found that patients with DBL have a significantly higher risk of ASCVD and PVD compared to normolipidemic controls, as well as a higher risk of PVD compared to patients with FH. Adequate screening for DBL is vital to improve the clinical care and prevent the development of ASCVD in these patients.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Review
Biochemistry & Molecular Biology
Ioana Mozos, Corina Flangea, Daliborca C. Vlad, Cristina Gug, Costin Mozos, Dana Stoian, Constantin T. Luca, Jaroslaw O. Horbanczuk, Olaf K. Horbanczuk, Atanas G. Atanasov
Summary: Cardiovascular disorders are a major cause of mortality worldwide, and a diet rich in fruits and vegetables, particularly containing anthocyanins, can have beneficial effects on vascular health. Anthocyanins have been shown to improve endothelial function, reduce oxidative stress, and exhibit various anti-atherogenic, antihypertensive, and anti-inflammatory properties, among others.
Review
Biochemistry & Molecular Biology
Francesco Visioli
Summary: There is a heated debate about the usefulness of food bioactives as dietary supplements, which often overlooks scientific evidence and proper research outcomes. Some argue that health claims should be based on pharmacological parameters, while others believe that botanical history and basic biological evidence should be sufficient for marketing. The current regulatory impasse does not help resolve this issue.
Review
Cell Biology
Fang Wen, Yue Liu, Hongyu Wang
Summary: Cardiovascular diseases are a major public health concern in China, with a large number of patients suffering from CVD. Evaluating endothelial function is crucial for cardiovascular prevention and controlling risk factors through vascular health management can help prevent cardiovascular events. Peking University Shougang hospital is at the forefront of lifelong vascular health management, guiding effective strategies for CVD prevention.
Article
Ecology
Audrey J. Parish, Danny W. Rice, Vicki M. Tanquary, Jason M. Tennessen, Irene L. G. Newton
Summary: This study characterizes the bacterium Bombella apis associated with honey bee larvae and its impact on their nutritional resilience. The research shows that B. apis is the only bacterium capable of withstanding antimicrobial larval diet and can synthesize all essential amino acids. Analysis of genes reveals the recent acquisition of multiple amino acid transporters in B. apis ancestors. Moreover, honey bee larvae supplemented with B. apis experience less mass reduction under limited nutrition.
Review
Nutrition & Dietetics
Karen Pesqueda-Cendejas, Melissa Rivera-Escoto, Monica R. Meza-Meza, Bertha Campos-Lopez, Isela Parra-Rojas, Margarita Montoya-Buelna, Ulises de la Cruz-mosso
Summary: Systemic lupus erythematosus (SLE) is characterized by a bimodal mortality pattern related to clinical disease activity and cardiovascular disease (CVD). The high prevalence of CVD in SLE patients is believed to be caused by the complex interaction between traditional and non-traditional CVD risk factors. Additionally, nutritional approaches have the potential to reduce SLE severity and organ damage by modulating the development of CVD risk factors.
Review
Food Science & Technology
Fatemeh Hajizadeh-Sharafabad, Elham Sharifi Zahabi
Summary: This systematic review summarized the findings from human intervention studies on the effect of ALA on vascular function. It found that ALA may improve endothelial function by increasing the bioavailability of endothelium-derived nitric oxide, reducing oxidative stress and inflammation, while the impact on endothelium-independent vasodilation is limited.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Nutrition & Dietetics
Lea Tischmann, Tanja C. Adam, Ronald P. Mensink, Peter J. Joris
Summary: This study investigated the longer-term effects of soy nut consumption on vascular function and cardiometabolic risk markers in healthy older adults. The results showed that long-term soy nut intake improved endothelial function, reduced LDL-cholesterol concentrations, and lowered mean arterial pressure.
CLINICAL NUTRITION
(2022)
Review
Pharmacology & Pharmacy
Negin Parsamanesh, Arghavan Asghari, Saeed Sardari, Aida Tasbandi, Tannaz Jamialahmadi, Suowen Xu, Amirhossein Sahebkar
Summary: Resveratrol (RSV), a naturally occurring bioactive polyphenol found in grapes and red wine, modulates various events involved in endothelial dysfunction through multiple molecular targets, displaying endothelial protective effects.
PHARMACOLOGICAL RESEARCH
(2021)