Article
Critical Care Medicine
Rebecca A. Gersten, Bhavna Seth, Luis Arellano, Jessica Shore, Lanier O'Hare, Nina Patel, Zeenat Safdar, Rachana Krishna, Yolanda Mageto, Darlene Cochran, Kathleen Lindell, Sonye K. Danoff
Summary: The survey results show that most ILD providers use palliative care (PC) and are comfortable discussing it. The barriers to PC identified in the survey include perceived lack of local access to PC, lack of systematic tools to assess symptom burden, lack of established optimal timing of PC referral, and unclear need for specialized PC delivery.
Article
Hematology
Sameer Patel, Geordyn Hoge, Bryan Fellman, Sharanpreet Kaur, Yvonne Heung, Eduardo Bruera, David Hui
Summary: This study examined the trend in timing of outpatient palliative-care referrals over a 10-year period for patients with hematologic malignancies. The findings showed that patients were referred in a timely fashion, with earlier and greater numbers of referrals over time.
BRITISH JOURNAL OF HAEMATOLOGY
(2022)
Editorial Material
Oncology
Craig Gouldthorpe, Jenny Power, Amy Taylor, Andrew Davies
Summary: Palliative care has evolved from end-of-life care for advanced cancer patients to include symptom management and improvement of quality of life from cancer diagnosis. Specialist palliative care teams provide complex problem-solving and support for healthcare colleagues to deliver general palliative care.
Article
Oncology
Mariken E. Stegmann, Olaf P. Geerse, Lia van Zuylen, Larissa Nekhlyudov, Daan Brandenbarg
Summary: Not all cancer patients can be cured, and some with incurable cancer may live for a long period. However, they are often forgotten in research and clinical practice. The perspectives of palliative care or survivorship may not be enough to address the wide range of physical and psychosocial problems these patients encounter.
Article
Oncology
Yashna Nadkarni, Ivana Kukec, Pascale Gruber, Shaman Jhanji, Joanne Droney
Summary: Palliative care within ICU is beneficial for decision-making, symptom control, and end-of-life care. Trigger tools can help identify the need for palliative care referral during ICU admission, with the majority of patients warranting referral either before or during admission.
SUPPORTIVE CARE IN CANCER
(2022)
Review
Geriatrics & Gerontology
Li Mo, Yimin Geng, Yuchieh Kathryn Chang, Jennifer Philip, Anna Collins, David Hui
Summary: This systematic review reveals the lack of consensus on referral criteria for palliative care in dementia patients and emphasizes the importance of identifying timely triggers to standardize referral.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2021)
Article
Urology & Nephrology
Xue Li, Jin Kai Luo
Summary: This study provides comprehensive insights and evaluations regarding the understanding and perspectives of Chinese healthcare professionals and elderly individuals with chronic kidney disease on kidney supportive care (KSC). The findings suggest that the cultural ethos in China poses challenges to the widespread implementation of KSC, and there is a need to cultivate this strategy within the prevailing medical landscape.
Article
Geriatrics & Gerontology
Deven Lackraj, Dio Kavalieratos, Komal P. Murali, Yewei Lu, May Hua
Summary: Implementing a specialist palliative care program was associated with an increased likelihood of discharging patients with dementia to hospice following acute hospitalization, with no significant impact on secondary outcomes.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2021)
Review
Health Care Sciences & Services
Josselyn Velepucha-Iniguez, Patricia Bonilla Sierra, Eduardo Bruera
Summary: There is limited knowledge about inequalities in palliative care access for patients with intellectual disability. This scoping review aimed to identify barriers to accessing palliative care for these patients. The review found that the main barriers include under referral to palliative care, reduced access, communication difficulties, and limited knowledge and experience among health professionals. Further research and education are needed to address the palliative care needs of patients with intellectual disability.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2022)
Article
Urology & Nephrology
Helen H-L Chiu, Donna M. Murphy-Burke, Sarah A. Thomas, Yuriy Melnyk, Alexandra L. Kruthaup-Harper, Janghu (James) Dong, Ognjenka Djurdjev, Sushila Saunders, Adeera Levin, Mohamud Karim, Gaylene M. Hargrove
Summary: The article discusses the integration of palliative care into the care of patients with chronic kidney disease within a provincial network structure. By establishing a multidisciplinary group, developing tools, and resources, and following recommendations for the four pillars of palliative care, it successfully facilitated culture change and long-term care planning.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2021)
Article
Surgery
Katherine C. Lee, Anne M. Walling, Steven S. Senglaub, Rachelle Bernacki, Lee A. Fleisher, Marcia M. Russell, Neil S. Wenger, Zara Cooper
Summary: This study aimed to develop a set of quality indicators to measure access to and the quality of primary palliative care (PC) delivered to seriously ill surgical patients. After two rounds of rating by an expert panel, a total of 24 indicators were rated as valid, covering various phases of surgical care.
Article
Oncology
Hon Wai Benjamin Cheng
Summary: The rapid escalation of COVID-19 cases worldwide poses a high mortality risk for individuals with preexisting conditions, including cancer patients. Palliative care workers play a crucial role in responding to COVID-19 by ensuring timely symptom management, potentially redeploying staff for psychosocial support, and utilizing technology for communication with patients.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Clinical Neurology
Anna-Christin Willert, Christoph J. Ploner, Alexander B. Kowski
Summary: This retrospective analysis of 130 patients admitted via the emergency department and later receiving palliative care in a neurological ward revealed that the main reasons for acute admission were epileptic seizures, gait disorders, disturbance of consciousness, pain, nutritional problems, or paresis. The study suggests that documenting the palliative situation and treatment limitations may help prevent unnecessary hospitalization, as emergency department assessment may not fully address all multidimensional needs, especially psychosocial problems. Future investigations should focus on developing short screening tools to identify palliative care needs of neurological patients in the emergency department.
FRONTIERS IN NEUROLOGY
(2021)
Article
Urology & Nephrology
Louis H. Diamond, Nancy C. Armistead, Dale E. Lupu, Alvin H. Moss
Summary: The article advocates for providing supportive care for patients with kidney disease, promoting a more patient-centered care approach, and emphasizes the need for urgent policy changes to improve the quality of life for patients.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2021)
Article
Oncology
Keita Tagami, Kento Masukawa, Akira Inoue, Tatsuya Morita, Yusuke Hiratsuka, Mamiko Sato, Katsura Kohata, Noriaki Satake, Yoshiyuki Kizawa, Satoru Tsuneto, Yasuo Shima, Mitsunori Miyashita
Summary: Appropriate timing for SPC referrals for advanced cancer patients and their families is associated with the quality of death, with findings suggesting that the appropriate timing is at the time of diagnosis or during anti-cancer treatment.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Urology & Nephrology
Manjula Kurella Tamura, Sarah Gaussoin, Nicholas M. Pajewski, Greg Zaharchuk, Barry Freedman, Stephen R. Rapp, Alexander P. Auchus, William E. Haley, Suzanne Oparil, Jessica Kendrick, Christianne L. Roumie, Srinivasan Beddhu, Alfred K. Cheung, Jeff D. Williamson, John A. Detre, Sudipto Dolui, R. Nick Bryan, Ilya M. Nasrallah
Summary: This study aimed to investigate the effects of intensive blood pressure control on cerebral perfusion and structure in individuals with and without chronic kidney disease (CKD). The findings suggest that intensive blood pressure treatment in adults with early kidney disease does not appear to have a detrimental effect on brain perfusion or structure.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2022)
Article
Urology & Nephrology
Vishal Duggal, Maria E. Montez-Rath, I-Chun Thomas, Mary K. Goldstein, Manjula Kurella Tamura
Summary: Current guidelines for nephrology referral based on laboratory criteria may not accurately identify patients at risk for kidney failure. This study suggests that using predicted risk of kidney failure as a referral criterion may help identify higher-risk patients and potentially reduce referral volume.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2022)
Article
Surgery
Wilson M. Alobuia, Tong Meng, Robin M. Cisco, Dana T. Lin, Insoo Suh, Manjula Kurella Tamura, Amber W. Trickey, Electron Kebebew, Carolyn D. Seib
Summary: The study found that racial/ethnic disparities exist in the management of primary hyperparathyroidism among older adults, with Black and Hispanic patients less likely to be evaluated by a surgeon and undergo parathyroidectomy compared to White patients. Urgent attention is needed to address the factors contributing to these disparities in order to achieve parity in the management of primary hyperparathyroidism.
Article
Clinical Neurology
Nicholas M. Pajewski, Fanny M. Elahi, Manjula Kurella Tamura, Jason D. Hinman, Ilya M. Nasrallah, Joachim H. Ix, Lindsay M. Miller, Lenore J. Launer, Clinton B. Wright, Mark A. Supiano, Alan J. Lerner, Tiffany L. Sudduth, Anthony A. Killeen, Alfred K. Cheung, David M. Reboussin, Donna M. Wilcock, Jeff D. Williamson
Summary: Intensive blood pressure treatment was associated with changes in NfL, which were correlated with changes in kidney function associated with intensive treatment.
ALZHEIMERS & DEMENTIA
(2022)
Article
Medicine, General & Internal
Carolyn D. Seib, Tong Meng, Insoo Suh, Alex H. S. Harris, Kenneth E. Covinsky, Dolores M. Shoback, Amber W. Trickey, Electron Kebebew, Manjula Kurella Tamura
Summary: This study compared the incidence of clinical fracture among older adults with PHPT who underwent parathyroidectomy vs nonoperative management. It found that parathyroidectomy was associated with a lower risk of any fracture and hip fracture, suggesting a clinically meaningful benefit of operative management in this population.
JAMA INTERNAL MEDICINE
(2022)
Article
Endocrinology & Metabolism
Carolyn D. Seib, Calyani Ganesan, Katherine D. Arnow, Alan C. Pao, John T. Leppert, Nicolas B. Barreto, Electron Kebebew, Manjula Kurella Tamura
Summary: A longitudinal cohort study found that patients with primary hyperparathyroidism (PHPT) who underwent parathyroidectomy were at a higher risk of kidney stone events in the immediate years after treatment compared to those managed nonoperatively, although the adjusted risk declined over time.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Surgery
Carolyn D. Seib, Tong Meng, Robin M. Cisco, Insoo Suh, Dana T. Lin, Alex H. S. Harris, Amber W. Trickey, Manjula K. Tamura, Electron Kebebew
Summary: This study compared the incidence of adverse cardiovascular events in older adults with primary hyperparathyroidism treated with parathyroidectomy versus nonoperative management. The results showed that parathyroidectomy was associated with a lower incidence of cardiovascular events compared to nonoperative management, which is relevant for patients with a long life expectancy.
Article
Health Care Sciences & Services
Fahad Saeed, Susan Ladwig, Rebecca Jane Allen, Nwamaka D. Eneanya, Manjula Kurella Tamura, Kevin A. Fiscella
Summary: This study investigated racial disparities in prognostic discussions, beliefs about future health, and completion of advance care planning (ACP)-related documents among Black and White patients receiving maintenance dialysis. The results showed that there were differences in health expectations and completion of ACP-related documents between Black and White patients. Therefore, systemic efforts are needed to investigate differences in health beliefs and address racial disparities in the completion of ACP-related documents.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2023)
Article
Endocrinology & Metabolism
Carolyn Dacey Seib, Tong Meng, Robin M. Cisco, Dana T. Lin, Elizabeth A. McAninch, Julie Chen, Manjula Kurella Tamura, Amber W. Trickey, Electron Kebebew
Summary: The objective of this study was to determine the incidence of permanent hypoparathyroidism requiring calcitriol therapy among older adults undergoing total thyroidectomy for Graves' disease in the United States. The study found that the risk of permanent hypoparathyroidism was low and should not deter surgical management for Graves' disease in older adults.
Article
Medicine, General & Internal
Carolyn D. Seib, Calyani Ganesan, Adam Furst, Alan C. Pao, Glenn M. Chertow, John T. Leppert, Insoo Suh, Maria E. Montez-Rath, Alex H. S. Harris, Amber W. Trickey, Electron Kebebew, Manjula Kurella Tamura
Summary: The effect of parathyroidectomy on long-term kidney function in patients with primary hyperparathyroidism (PHPT) and reduced eGFR was investigated. The study found that parathyroidectomy did not have a significant impact on long-term kidney function in older adults with PHPT.
ANNALS OF INTERNAL MEDICINE
(2023)
Letter
Health Care Sciences & Services
Fahad Saeed, Amaka Eneanya, Rebecca J. Allen, Manjula K. Tamura, Kevin A. Fiscella
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2023)
Article
Medicine, General & Internal
Susan P. Y. Wong, David K. Prince, Manjula Kurella Tamura, Yoshio N. Hall, Catherine R. Butler, Ruth A. Engelberg, Elizabeth K. Vig, J. Randall Curtis, Ann M. O'Hare
Summary: This study examines the relationship between patients' health care values and their engagement in advance care planning and end-of-life care. The findings suggest a discrepancy between patients' expressed values and their actual involvement in advance care planning and end-of-life care.
JAMA INTERNAL MEDICINE
(2023)
Editorial Material
Urology & Nephrology
Vivek Charu, Lu Tian, Manjula Kurella Tamura, Maria E. Montez-Rath
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2023)
Article
Clinical Neurology
C. Shah, D. Srinivasan, G. Erus, M. Kurella Tamura, M. Habes, J. A. Detre, W. E. Haley, A. J. Lerner, C. B. Wright, J. T. Wright Jr, S. Oparil, S. B. Kritchevsky, H. A. Punzi, A. Rastogi, R. Malhotra, C. H. Still, J. D. Williamson, R. N. Bryan, Y. Fan, I. M. Nasrallah
Summary: The study demonstrates that intensive treatment for hypertension can slow the progression of cerebral white matter hyperintensities and is associated with changes in functional brain connectivity. Specifically, the auditory-salience-language network showed a significant decline in connectivity score in the standard treatment group compared to the intensive treatment group. Additionally, changes in the mean connectivity score of the default mode network correlated significantly with changes in white matter hyperintensities.
AMERICAN JOURNAL OF NEURORADIOLOGY
(2023)
Meeting Abstract
Health Care Sciences & Services
Jessica Ma, Ariadna Garcia, Anne C. Black, Karleen Giannitrapani, Derek Boothroyd, Manjula K. Tamura, I-Chun Thomas, Amanda Midboe, Lara K. Troszak, Shiqi Zhang, Selen Bozkurt, Devon Check, Jessica S. Merlin, Barrett Bowling, William Becker, Lorenz Karl
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
