期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 55, 期 5, 页码 1801-1804出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201510661
关键词
alkaloids; domino reactions; heterocycles; natural products; total synthesis
资金
- Swedish Research Council
- Carl Tryggers Foundation
- Crafoord Foundation
- Swedish Institute
- Lund University
Perophoramidine, dehaloperophoramidine, and communesin F are structurally related alkaloids having intriguing polycyclic structures. A strategy for the synthesis of dehaloperophoramidine has been developed. In this synthesis all skeletal atoms and all functional groups required to reach the target molecule are incorporated early in the sequence. This approach led to the discovery of two novel substrate-specific domino processes, one encompassing four steps and the other comprising five steps, thus resulting in an eight-step synthesis of dehaloperophoramidine.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据