Article
Agriculture, Dairy & Animal Science
Stella Agradi, Paola Cremonesi, Laura Menchetti, Claudia Balzaretti, Marco Severgnini, Federica Riva, Bianca Castiglioni, Susanna Draghi, Alessia Di Giancamillo, Marta Castrica, Daniele Vigo, Silvia Clotilde Modina, Valentina Serra, Alda Quattrone, Elisa Angelucci, Grazia Pastorelli, Giulio Curone, Gabriele Brecchia
Summary: BC is a nutraceutical that can modulate intestinal microbiota. This study investigates the effects of BC diet supplementation on luminal and mucosa-associated microbiota in the jejunum, caecum, and colon of rabbits. Significant differences were found in the microbial composition of the three groups, especially in the caecum and colon of the 2.5% BC group. A functional prediction has revealed several altered pathways in BC groups, with particular reference to amino acids and lactose metabolism. Findings suggest that BC supplementation could positively affect the intestinal microbiota.
Article
Nutrition & Dietetics
Cristina Politi, Marco Mobrici, Rosa Maria Parlongo, Belinda Spoto, Giovanni Tripepi, Patrizia Pizzini, Sebastiano Cutrupi, Daniele Franco, Renato Tino, Giuseppe Farruggio, Chiara Failla, Flavia Marino, Giovanni Pioggia, Alessandra Testa
Summary: This cross-sectional study investigated the gut microbiota composition in an adult population from the southernmost area of Italy. Significant differences were found between overweight and normal-weight individuals, with overweight individuals having lower levels of Akkermansia and Bifidobacterium. The Firmicutes/Bacteroidetes ratio was inversely associated with BMI, indicating a possible role in disease susceptibility.
Review
Health Care Sciences & Services
Irina N. Grigor'eva
Summary: Obesity is a major risk factor for developing gallstone disease, possibly related to alterations in the gut microbiota. Studies on the gut microbiota in patients with GSD have shown significant changes in specific bacterial phyla. The impact of GSD on microbial diversity and the Firmicutes/Bacteroidetes ratio remains unclear.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Microbiology
Gao Long, Yuting Hu, Enfu Tao, Bo Chen, Xiaoli Shu, Wei Zheng, Mizu Jiang
Summary: Cesarean section delivery significantly affects the composition and development of gut microbiota in infants, resulting in decreased relative abundance of certain bacteria and alterations in specific functional genes. The study findings provide new insights into strategies for preventing Cesarean section-related disorders in later life.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Microbiology
Manal Ali Ahmad, Mirey Karavetian, Carole Ayoub Moubareck, Gabi Wazz, Tarek Mahdy, Koen Venema
Summary: This study found differences in gut microbiota composition between obese and lean adult Emiratis, as well as associations between certain microbial genera and obesity. These findings highlight the potential relationship between gut microbiota and obesity, and further research is warranted.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Endocrinology & Metabolism
Filippo Biscarini, Giulia Masetti, Ilaria Muller, Hedda Luise Verhasselt, Danila Covelli, Giuseppe Colucci, Lei Zhang, Mohd Shazli Draman, Onyebuchi Okosieme, Pete Taylor, Chantal Daumerie, Maria-Cristina Burlacu, Michele Marino, Daniel George Ezra, Petros Perros, Sue Plummer, Anja Eckstein, Mario Salvi, Julian R. Marchesi, Marian Ludgate
Summary: This study compared the fecal microbiota in patients with hyperthyroidism caused by Graves disease (GD) and varying severity of Graves orbitopathy (GO) with healthy controls. The results showed an increase in Actinobacteria and a decrease in Bacteroidetes in GD/GO patients compared to controls. A higher Firmicutes to Bacteroidetes ratio was observed in GD/GO. Longitudinal analysis revealed a correlation between the presence of certain bacteria (Clostridiales) at diagnosis and the persistence of thyroid antibodies even after antithyroid drug treatment.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Mathematical & Computational Biology
Fei Fan, Zhaoxiang Bian, Xuan Zhang, Hongwei Wu, Simeng Wang, Si Zhang, Qiong Wang, Fei Han
Summary: This article explores the association between gut microbiota and Tic disorder (TD) through big data analytics. The findings suggest taxonomic differences in gut microbiota composition between TD cases and controls. However, no consensus was reached regarding diversity measurements.
FRONTIERS IN COMPUTATIONAL NEUROSCIENCE
(2022)
Review
Biochemistry & Molecular Biology
Ruxandra Florentina Ionescu, Robert Mihai Enache, Sanda Maria Cretoiu, Bogdan Severus Gaspar
Summary: This article summarizes the recent findings on the correlation between gestational diabetes mellitus (GDM) and dysbiosis, as well as the prevention and treatment methods. The most common changes in the microbiome of GDM patients are an increase in Firmicutes phylum or a decrease in Bacteroidetes and Actinobacteria phyla. Gut dysbiosis persists postpartum and affects the development of newborns. Probiotic supplementation and regular physical activity have strong evidence in controlling blood glucose levels.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Microbiology
Patin Sililas, Lingling Huang, Chanisa Thonusin, Suchaya Luewan, Nipon Chattipakorn, Siriporn Chattipakorn, Theera Tongsong
Summary: The study found that maternal Lactobacillales was decreased before delivery in both non-GDM and GDM groups, with a higher Firmicutes/Bacteroidetes (F/B) ratio in the GDM group. However, there was no difference in neonatal gut microbiota between the groups. Further research comparing gut microbiota composition among different GDM treatment groups is needed to better understand the role of gut microbiota in the development of GDM.
Article
Immunology
Na Wu, Jingwei Zhou, Heng Mo, Qing Mu, Huiting Su, Mei Li, Yimeng Yu, Aiyu Liu, Qi Zhang, Jun Xu, Weidong Yu, Peng Liu, Guoli Liu
Summary: This study analyzed the gut microbiota composition of 27 GDM and 30 healthy subjects, identifying specific bacteria associated with GDM, blood glucose levels, and obesity. The study also found that short-term diet management in GDM is associated with changes in specific bacteria, rather than an alternative gut microbial pattern. These findings have important implications for understanding the effects of diet intervention on the gut microbiota and metabolism in pregnant women with GDM.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Gastroenterology & Hepatology
Sara A. Zahran, Marwa Ali-Tammam, Amal E. Ali, Ramy K. Aziz
Summary: This study found that stool samples with higher azo-reducing activity were enriched in Firmicutes but with relatively fewer Bacteroidetes. Multivariate analysis confirmed the Firmicutes proportion as a major variable distinguishing high and non-azo-reducers. More samples and studies from different geographical areas are needed to support this conclusion.
Article
Food Science & Technology
Ko-Chung Tsui, Ting-Lin Yen, Chi-Jung Huang, Kun-Jing Hong
Summary: The study investigated the effects of pretreatment with Lactobacillus rhamnosus GG (LGG) on sepsis survival and alterations in gut microbiota, blood cytokines, and chemokines in a mouse model. Results showed that LGG improved survival from LPS-induced sepsis by altering gut microbiota and reducing the host immune system's reactivity to pathogens.
FOOD SCIENCE & NUTRITION
(2021)
Article
Agriculture, Dairy & Animal Science
Haiwen Zhang, Liangmin Huang, Shihui Hu, Xinyun Qin, Xuemei Wang
Summary: This study found that 5% MOLP can improve the growth performance and carcass characteristics of broiler chickens by regulating the relative abundance of intestinal flora. The results of this study can provide some reference for the application of MOLP in livestock and poultry farming.
Article
Microbiology
Akarsh Mathrani, Louise W. Lu, Ivana R. Sequeira-Bisson, Marta P. Silvestre, Michael Hoggard, Daniel Barnett, Mikael Fogelholm, Anne Raben, Sally D. Poppitt, Michael W. Taylor
Summary: Obesity-related metabolic diseases, such as type 2 diabetes, are prevalent worldwide. Ethnicity plays a role in susceptibility to these diseases, and the gut microbiota may also have an influence. This study compared the fecal microbiota of European-ancestry and Chinese-ancestry cohorts with overweight and prediabetes in New Zealand, revealing significant microbiota differences between the ethnicities.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Parul Singh, Arun Rawat, Marwa Saadaoui, Duaa Elhag, Sara Tomei, Mohammed Elanbari, Anthony K. Akobeng, Amira Mustafa, Ibtihal Abdelgadir, Sharda Udassi, Mohammed A. Hendaus, Souhaila Al Khodor
Summary: A study found that pediatric vitamin D inadequacy significantly impacts the gut microbiota, highlighting the importance of considering host genetics and baseline gut microbiome composition in interpreting the clinical outcomes related to vitamin D deficiency and designing personalized therapeutic interventions.