Article
Public, Environmental & Occupational Health
A. J. Beswick, C. Fry, C. R. Bradley, T. Pottage, S. Sharpe, C. F. Haill, M. A. Mugglestone, A. Bak, G. L. Marsden, A. Bennett, M. Garvey, A. P. R. Wilson
Summary: This report provides advice on employing automated room decontamination devices for infection prevention and control. It emphasizes the effectiveness and safety of automated systems compared to conventional methods, and discusses the use of different chemicals and devices. The report also highlights the increasing choices in the marketplace and the potential confusion for end users.
JOURNAL OF HOSPITAL INFECTION
(2022)
Article
Health Care Sciences & Services
Amani Alnimr, Aisha Alamri, Khaled F. Salama, Mahmoud Radi, Huda Bukharie, Bashayer Alshehri, Ali A. Rabaan, Mohammed Alshahrani
Summary: This study provides evidence of SARS-CoV-2 shedding in the hospital environment and shows the efficacy of AHP in eliminating the virus.The viral shedding was directly related to the distance from the patient, and AHP was successful in eliminating the viral genome, indicating the hospital environment as a possible source of infection that requires further cost-effectiveness studies.
RISK MANAGEMENT AND HEALTHCARE POLICY
(2021)
Article
Public, Environmental & Occupational Health
R. Saliba, T. Ghelfenstein-Ferreira, A. Lomont, B. Pilmis, E. Carbonnelle, D. Seytre, E. Nasser-Ayoub, J-R Zahar, D. Karam-Sarkis
Summary: The study evaluated and compared factors associated with environmental contamination around carriers of different MDROs, finding that hospital environmental contamination rates are substantially higher for patients with VRE compared to those with ESBL-PE and CPE. Further studies on a larger scale are needed to confirm the validity of these findings.
JOURNAL OF HOSPITAL INFECTION
(2021)
Article
Food Science & Technology
Cathrine Finne Kure, Solveig Langsrud, Trond Moretro
Summary: The study assesses the fungicidal effect of a H2O2 mist generating system on food-related mould spores dried on stainless steel. Results show >3 log reduction in mould spores after exposure to H2O2 mist for 2 or 4 hours, with raw meat juice having an adverse effect on Penicillium and Mucor in some tests. The research confirms the efficiency of H2O2 mist in reducing food-related mould spores on surfaces.
Article
Medicine, Legal
Alexandra Mayer, Mansa Nair, Gordon Miskelly
Summary: This study investigated the oxidative decontamination of methamphetamine and ephedrine hydrochloride using a commercially available H2O2-based decontamination product. The degradation kinetics of methamphetamine and ephedrine hydrochloride were observed and major oxidation products were identified. The study provides useful information for further research on the behavior and persistence of these reaction products.
FORENSIC SCIENCE INTERNATIONAL
(2023)
Review
Engineering, Environmental
Zhong Chen, Ducheng Yao, Chengcheng Chu, Shun Mao
Summary: This article introduces strategies for improving the efficiency of photocatalytic H2O2 production and discusses its potential and challenges in environmental applications.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Environmental Sciences
Anupkumar Bhaskarapillai, Padala A. Nishad, A. L. Rufus
Summary: The study investigated an oxidative process using hydrogen peroxide to dissolve metallic antimony, strip dissolved antimony ions, and ensure compatibility with structural materials in nuclear reactor coolant systems. This process can effectively remove antimony activity and reduce radiation exposure to workers. The presence of hydrogen peroxide increased the rate of dissolution of metallic antimony. Three substrates, including strong base anion exchange resin and two chitosan-TiO2 based substrates, were equally efficient in removing dissolved antimony. The process could dissolve antimony without significant re-deposition on the oxide coated carbon steel surface and dissolve antimony incorporated in the oxide film of zircaloy. Corrosion compatibility tests showed that only Monel-400 underwent pitting attack at pH 10.2.
Article
Public, Environmental & Occupational Health
Birte Knobling, Gefion Franke, Eva M. Klupp, Cristina Belmar Campos, Johannes K. Knobloch
Summary: This study evaluated the effectiveness of automated room decontamination devices, comparing aerosolized hydrogen peroxide (aHP) with a gaseous ozone-based device. The results showed that the gaseous ozone-based device had better bactericidal effects, compared to the aHP system which only achieved complete elimination of realistic bioburden after a longer exposure time. Further research and development is needed to understand the toxicity, efficacy and safety of these devices in complex hospital conditions.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Jennifer Sanguinet, Charles Edmiston
Summary: This study demonstrates the effectiveness of dry hydrogen peroxide (DHP) in reducing air and surface microbial contamination in various settings within a large hospital, with the greatest reductions achieved on privacy curtains.
AMERICAN JOURNAL OF INFECTION CONTROL
(2021)
Review
Immunology
Arsheena Yassin, Mariya Huralska, Jason M. Pogue, Deepali Dixit, Robert G. Sawyer, Keith S. Kaye
Summary: The prevalence of multidrug-resistant gram-negative bacterial infections has significantly increased in the past decade, leading to higher rates of morbidity and mortality. Treating these infections presents challenges, particularly for critically ill patients with limited margin for error. The availability of new therapies has improved treatment options, but optimal clinical and therapeutic approaches for managing these infections still need to be established.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Nanoscience & Nanotechnology
Yuanzhu Zhao, Lina Wang, Richard Malpass-Evans, Neil B. McKeown, Mariolino Carta, John P. Lowe, Catherine L. Lyall, Remi Castaing, Philip J. Fletcher, Gabriele Kociok-Kohn, Jannis Wenk, Zhenyu Guo, Frank Marken
Summary: In this study, graphitic carbon nitride (g-C3N4) was embedded into a polymer host to create recoverable photocatalysts with enhanced hydrogen peroxide production.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Letter
Infectious Diseases
Amanda Zaman, Taha Qazi, Pooja Pai, Patricia Peters, Susie Nicolaysen, Scott W. Olesen
Summary: Careful consideration is needed when selecting research methodologies and using data sources. Using SINAN data as a proxy for invasive pneumococcal disease in Brazil may result in underestimations of cases.
LANCET INFECTIOUS DISEASES
(2021)
Review
Engineering, Environmental
Andrea Hicks, Sila Temizel-Sekeryan, Wissam Kontar, Ramin Ghamkhar, Monica Rodriguez Morris
Summary: The COVID-19 pandemic is expected to last at least 18 months, highlighting a critical shortage of PPE in the United States. Adequate respiratory protection is essential, with reusable options potentially being more cost-effective.
RESOURCES CONSERVATION AND RECYCLING
(2021)
Review
Public, Environmental & Occupational Health
Caroline M. van der Starre, Suzan A. J. Cremers-Pijpers, Carsten van Rossum, Edmee C. Bowles, Alma Tostmann
Summary: This article reviews the in situ efficacy of automated whole room disinfection (WRD) devices in a hospital setting and compares it to the in vitro efficacy. The results show that all four types of WRD systems are effective in reducing pathogens in the hospital environment.
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2022)
Article
Nursing
Ayse Akbiyik, Selcuk Kaya, Murat Aksun
Summary: This study aimed to determine the bacterial contamination of needleless connectors before and after disinfection, and assess the risk for catheter-related bloodstream infections. It was found that 91.7% of needleless connectors were contaminated with bacteria before disinfection, mainly with coagulase-negative staphylococci and Staphylococcus aureus. Bacterial growth was not detected on the connectors after disinfection, highlighting the importance of disinfecting before use.
INTENSIVE AND CRITICAL CARE NURSING
(2023)
Article
Public, Environmental & Occupational Health
John Frederick, Alexandria C. Brown, Derek A. Cummings, Charlotte A. Gaydos, Cynthia L. Gibert, Geoffrey J. Gorse, Jenna G. Los, Ann-Christine Nyquist, Trish M. Perl, Connie S. Price, Lewis J. Radonovich, Nicholas G. Reich, Maria C. Rodriguez-Barradas, Mary T. Bessesen, Michael S. Simberkoff
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2018)
Article
Multidisciplinary Sciences
Stephen A. Lauer, Krzysztof Sakrejda, Evan L. Ray, Lindsay T. Keegan, Qifang Bi, Paphanij Suangtho, Soawapak Hinjoy, Sopon Iamsirithaworn, Suthanun Suthachana, Yongjua Laosiritaworn, Derek A. T. Cummings, Justin Lessler, Nicholas G. Reich
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2018)
Article
Multidisciplinary Sciences
Nicholas G. Reich, Justin Lessler, Jay K. Varma, Neil M. Vora
SCIENTIFIC REPORTS
(2018)
Article
Biochemical Research Methods
Evan L. Ray, Nicholas G. Reich
PLOS COMPUTATIONAL BIOLOGY
(2018)
Article
Multidisciplinary Sciences
Nicholas G. Reich, Logan C. Brooks, Spencer J. Fox, Sasikiran Kandula, Craig J. McGowan, Evan Moore, Dave Osthus, Evan L. Ray, Abhinav Tushar, Teresa K. Yamana, Matthew Biggerstaff, Michael A. Johansson, Roni Rosenfeld, Jeffrey Shaman
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2019)
Letter
Multidisciplinary Sciences
Nicholas G. Reich, Dave Osthus, Evan L. Ray, Teresa K. Yamana, Matthew Biggerstaff, Michael A. Johansson, Roni Rosenfeld, Jeffrey Shaman
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2019)
Article
Biochemical Research Methods
Nicholas G. Reich, Craig J. McGowan, Teresa K. Yamana, Abhinav Tushar, Evan L. Ray, Dave Osthus, Sasikiran Kandula, Logan C. Brooks, Willow Crawford-Crudell, Graham Casey Gibson, Evan Moore, Rebecca Silva, Matthew Biggerstaff, Michael A. Johansson, Roni Rosenfeld, Jeffrey Shaman
PLOS COMPUTATIONAL BIOLOGY
(2019)
Article
Mathematical & Computational Biology
Alexandria C. Brown, Stephen A. Lauer, Christine C. Robinson, Ann-Christine Nyquist, Suchitra Rao, Nicholas G. Reich
STATISTICS IN MEDICINE
(2020)
Article
Biochemical Research Methods
Graham Casey Gibson, Kelly R. Moran, Nicholas G. Reich, Dave Osthus
Summary: Accurate influenza forecasting is crucial for resource allocation and response planning. A study found that imposing geographical constraints on forecast collections improved the accuracy of 79% of models.
PLOS COMPUTATIONAL BIOLOGY
(2021)
Article
Multidisciplinary Sciences
Nicholas G. Reich, Matthew Cornell, Evan L. Ray, Katie House, Khoa Le
Summary: Forecasting plays a crucial role in decision-making, and a new data model for probabilistic predictions has been introduced. This model clearly defines the parts of a forecast and offers an approach to representing data elements. The data model is implemented in the Zoltar software application, which stores forecasts and provides standardized API access.
Article
Mathematical & Computational Biology
Thomas McAndrew, Nicholas G. Reich
Summary: A new adaptive ensemble approach is proposed to update weights in real-time during the seasonal influenza epidemic, improving prediction accuracy. By adjusting the regularization value through a regularized likelihood method, the adaptive ensemble outperforms an equal-weight ensemble and achieves similar performance to a static ensemble.
STATISTICS IN MEDICINE
(2021)
Article
Medicine, General & Internal
Simon Pollett, Michael A. Johansson, Nicholas G. Reich, David Brett-Major, Sara Y. Del Valle, Srinivasan Venkatramanan, Rachel Lowe, Travis Porco, Irina Maljkovic Berry, Alina Deshpande, Moritz U. G. Kraemer, David L. Blazes, Wirichada Pan-ngum, Alessandro Vespigiani, Suzanne E. Mate, Sheetal P. Silal, Sasikiran Kandula, Rachel Sippy, Talia M. Quandelacy, Jeffrey J. Morgan, Jacob Ball, Lindsay C. Morton, Benjamin M. Althouse, Julie Pavlin, Wilbert van Panhuis, Steven Riley, Matthew Biggerstaff, Cecile Viboud, Oliver Brady, Caitlin Rivers
Summary: The EPIFORGE checklist is a guideline developed for standardized reporting of epidemic forecasting research, aiming to improve the consistency, reproducibility, comparability, and quality of reporting in this field.
Article
Biochemical Research Methods
Thomas McAndrew, Nicholas G. Reich
Summary: Experts provided quantitative predictions and estimates of trends in the emerging COVID-19 pandemic early on, and aggregating these predictions could offer more consistently accurate results.
PLOS COMPUTATIONAL BIOLOGY
(2022)
Article
Mathematical & Computational Biology
Nutcha Wattanachit, Evan L. Ray, Thomas C. McAndrew, Nicholas G. Reich
Summary: Three different methods of influenza forecasting were compared in terms of their performance during the 2016/2017, 2017/2018, and 2018/2019 influenza seasons. The use of beta transformation in the models was found to produce more accurate predictions and reduce the impact of the flu epidemic.
STATISTICS IN MEDICINE
(2023)
Article
Statistics & Probability
Xiaofei Wang, Nicholas G. Reich, Nicholas J. Horton
AMERICAN STATISTICIAN
(2019)