Article
Immunology
Fabrizio Bert, Antonino Russotto, Alex Pivi, Benedetta Mollero, Gianluca Voglino, Giancarlo Orofino, Roberta Siliquini
Summary: This study evaluated the KAP of PLWH regarding vaccines and trust in the Italian NHS. A survey involving 160 HIV-positive patients was conducted at a hospital in Turin, Italy. Results showed that some patients had hesitations or misconceptions about vaccination and there were concerns about trust in the Italian NHS and communication by healthcare workers.
Article
Agriculture, Dairy & Animal Science
Anna Lisa Voss, Wolfgang Heuwieser, John F. Mee, Carola Fischer-Tenhagen
Summary: A questionnaire was designed to ask two groups of veterinarians about calving management. Differentiating between the stages of parturition was seen as beneficial, but there was no consensus on the timing of moving cows to the maternity pen. The two veterinary groups had similar knowledge levels in calving management.
Article
Emergency Medicine
James S. Ford, Tasleem Chechi, Michella Otmar, Melissa Baker, Sarah Waldman, Brittany Morgan, David Tan, Nam K. Tran, Larissa May
Summary: The study demonstrates that utilizing an electronic health record alert to prompt syphilis testing in patients undergoing gonorrhoea/chlamydia testing can increase the number of syphilis tests and diagnoses while potentially reducing clinician bias in testing.
EMERGENCY MEDICINE JOURNAL
(2022)
Article
Immunology
John D. Ditekemena, Dalau M. Nkamba, Armand Mutwadi, Hypolite M. Mavoko, Joseph Nelson Siewe Fodjo, Christophe Luhata, Michael Obimpeh, Stijn Van Hees, Jean B. Nachega, Robert Colebunders
Summary: The willingness for COVID-19 vaccination among citizens of the DRC is currently low, especially among healthcare workers. A large sensitization campaign will be needed to increase COVID-19 vaccine acceptance.
Article
Medicine, General & Internal
Biruk Befekadu, Muluneh Shuremu, Asrat Zewdie
Summary: This study aimed to assess the prevalence of syphilis and associated factors among pregnant women with antenatal care follow-up. The results showed a syphilis prevalence of 1.4% among pregnant women, and education level, husband's history of substance use, antenatal care, age at marriage, and knowledge about syphilis were identified as independent predictors of syphilis.
Article
Veterinary Sciences
Joel Fernando Soares Filipe, Stefania Lauzi, Lucrezia Pina, Paola Dall'Ara
Summary: This study in Italy found that the majority of cats (91%) were vaccinated, with 80% of cats vaccinated in the last 3 years. Veterinarians play a significant role in owners' decision-making process, with cat owners trusting their advice on vaccination.
BMC VETERINARY RESEARCH
(2021)
Review
Public, Environmental & Occupational Health
Bayissa Chala, Feyissa Hamde
Summary: Vector-borne emerging and re-emerging diseases pose significant public health challenges globally. Interactions among pathogens, hosts, environment, and social demographic factors are key to the emergence and re-emergence of these diseases. Ongoing evolution of pathogens, population growth, urbanization, and climate change are among the factors linked with the appearance and resurgence of vector-borne infectious diseases.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Medicine, General & Internal
Elisa Hendrika Adriaansens, Marieke E. C. van Winden, Peter van Wijngaarden
Summary: Diagnosing syphilis can be challenging due to its variable presentation. A case of a 56-year-old female patient with unilateral cervical lymphadenopathy and night sweats was initially undiagnosed, but eventually diagnosed through serologic testing for syphilis. Treatment delay can be reduced significantly by recognizing localized lymphadenopathy as a possible symptom of syphilitic disease, thereby preventing further spread and potential morbidity.
Article
Medicine, General & Internal
Cho Lee Wong, Alice W. Y. Leung, Oscar Man Hon Chung, Wai Tong Chien
Summary: This study explored factors influencing COVID-19 vaccination uptake among the general public in a developed country. The results showed that factors such as job affected by COVID-19, having an income source, perceived good/excellent physical health status, perceived COVID-19 exposure, good/excellent knowledge of COVID-19, learning about the vaccine from printed materials, and perceiving family members at risk of contracting COVID-19 were associated with vaccination uptake.
Article
Medicine, General & Internal
Christina Atchison, Leigh Robert Bowman, Charlotte Vrinten, Rozlyn Redd, Philippa Pristera, Jeffrey Eaton, Helen Ward
Summary: The study found that the majority of respondents adopted at least one preventive measure, with social distancing measures more common among those over 70 years old. Individuals with the lowest household income were less likely to work from home and self-isolate, while the ability to self-isolate was also lower in minority ethnic groups.
Article
Medicine, General & Internal
Mabel Carabali, Lauren Maxwell, Brooke Levis, Priya Shreedhar
Summary: This study aims to support the efforts of the Zika virus Individual Participant Data (IPD) Consortium by conducting a metadata survey to identify and provide an overview of study-level heterogeneity in exposure, outcome, and covariate ascertainment. The results highlight the challenges in accounting for within-study and between-study heterogeneity when conducting IPD-MAs of data collected in response to emergent pathogens like Zika virus.
Article
Medicine, General & Internal
Rawlance Ndejjo, Nuole Chen, Steven N. Kabwama, Alice Namale, Solomon Tsebeni Wafula, Irene Wanyana, Susan Kizito, Suzanne N. Kiwanuka, William Sambisa, Lily L. Tsai, Rhoda K. Wanyenze
Summary: This study examined the uptake of COVID-19 vaccines among adults in Uganda and found that 49.7% of the participants had received the vaccine. Older age, higher education, medium-income, and residence in certain regions were associated with vaccine uptake. Efforts should be made to increase access to vaccines and utilize health workers to enhance uptake.
Article
Medicine, General & Internal
Bofu Liu, Dongze Li, Yisong Cheng, Jing Yu, Yu Jia, Qin Zhang, Yanmei Liu, Yu Cao
Summary: The study proposed a simple and effective SSEPS scoring system to help emergency clinicians identify high-risk sepsis patients early, with good predictive value for patient outcomes.
Article
Infectious Diseases
Teck Chuan Voo, Angela Ballantyne, Chirk Jenn Ng, Benjamin J. Cowling, Jingyi Xiao, Kean Chang Phang, Sharon Kaur, Grazele Jenarun, Vishakha Kumar, Jane Mingjie Lim, Zaw Myo Tun, Nigel Chong Boon Wong, Clarence C. Tam
Summary: Based on a survey conducted in Singapore, Hong Kong, and Malaysia, public acceptance of COVID-19 control measures varies across the regions. Hong Kong respondents were less supportive of digital contact tracing and monitoring devices compared to those in Malaysia and Singapore. In Singapore, respondents expressed higher trust in local data protection rules. However, there was significant support for implementing differential travel restrictions based on vaccination status in all settings.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Medicine, General & Internal
Mahboubeh Haddad, Fereshte Sheybani, HamidReza Naderi, Mohammad Saeed Sasan, Mona Najaf Najafi, Malihe Sedighi, Atena Seddigh
Summary: The study investigated the most common errors in diagnosing infectious diseases and their causes. Errors were most frequently reported in diagnosing upper respiratory tract infections, tuberculosis, and pleuropulmonary infections, with the most common types of errors being generating a diagnostic hypothesis, history taking, and physical examination. Errors related to tuberculosis and intra-abdominal infections were associated with more-serious outcomes.
FRONTIERS IN MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Susan E. Beekmann, Hilary M. Babcock, Mark S. Rasnake, Thomas R. Talbot, Philip M. Polgreen
Summary: Most infectious disease specialists rated their facility's preparedness plan for early COVID-19 vaccination as excellent or adequate; vaccine hesitancy and concern about adverse reactions were the most commonly anticipated barriers to COVID-19 vaccination; only 60% believed that COVID-19 vaccination should be mandatory.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Laura Anderson, Emily Schmitz, Philip M. Polgreen, Susan E. Beekmann, Nasia Safdar
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Review
Medicine, Research & Experimental
Philip M. Polgreen, Alejandro P. Comellas
Summary: Cystic fibrosis is a genetic disorder caused by mutations in the CFTR gene, resulting in various medical conditions. Previously, carriers were not considered at risk for the associated diseases, but recent research suggests otherwise. Thus, there is a need for precise assessment of health risks for carriers.
ANNUAL REVIEW OF MEDICINE
(2022)
Article
Immunology
Aaron C. Miller, Logan M. Harris, Joseph E. Cavanaugh, Mahmoud Abou Alaiwa, David A. Stoltz, Douglas B. Hornick, Philip M. Polgreen
Summary: Infection-related visits and antibiotic use decreased significantly in patients with cystic fibrosis (CF) after initiating treatment with elexacaftor-tezacaftor-ivacaftor. This nonantimicrobial therapy appears to have a substantial impact on respiratory infections and antimicrobial use in CF patients.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Public, Environmental & Occupational Health
Thomas R. Talbot, Susan E. Beekmann, Hilary M. Babcock, Philip M. Polgreen
Summary: This study examined the exemption policies and practices for healthcare personnel (HCP) COVID-19 vaccine requirements. The results showed that many healthcare institutions allow different types of exemptions, but there is significant variation in the types of exemptions allowed and how the exemption programs are structured.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Article
Multidisciplinary Sciences
Andrew B. Janowski, Philip M. Polgreen, Susan E. Beekmann, Jason G. Newland
Summary: The perception of the transmission risks of SARS-CoV-2 in social and educational settings by US healthcare providers have different perspectives. High-risk activities identified include spending time in a bar, eating at a restaurant, and attending an indoor sporting event. Compared to students, teachers and pediatric providers have a lower perception of transmission risks.
Article
Immunology
Kapil K. Saharia, Shweta Anjan, Judy Streit, Susan E. Beekmann, Philip M. Polgreen, Matthew Kuehnert, Dorry L. Segev, John W. Baddley, Rachel A. Miller
Summary: Solid organ transplant recipients (SOTR) who have breakthrough infections after COVID-19 vaccination can develop severe and even critical illness. Two doses of COVID-19 vaccine may be insufficient to protect SOTR against severe disease and mortality.
TRANSPLANT INFECTIOUS DISEASE
(2022)
Article
Medicine, General & Internal
Manish Suneja, Susan E. Beekmann, Gurpreet Dhaliwal, Aaron C. Miller, Philip M. Polgreen
Summary: This study investigated the diagnostic delays in infectious diseases and found that the failure to consider the diagnosis initially and not ordering appropriate tests were the two most important contributing factors. Unusual clinical presentations and not consulting infectious diseases physicians early enough were also reported as causes of delays.
Article
Public, Environmental & Occupational Health
Michael J. Durkin, Jason Lake, Philip M. Polgreen, Susan E. Beekmann, Adam L. Hersh, Jason G. Newland
Summary: A survey of adult infectious diseases physicians revealed concerns about the unintended consequences of antimicrobial stewardship programs, such as disagreement with colleagues, provider autonomy, and remote recommendations. Non-ASP physicians expressed more concern about the focus on costs, provider efficiency, and unintended consequences of ASP guidance.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Urology & Nephrology
Jason M. Sandberg, Hayden L. Warner, Kevin J. Flynn, Shawn M. Sexton, Hanh Td Pham, Blaize W. Kandler, Phillip M. Polgreen, Bradley A. Erickson
Summary: This study evaluated the efficacy of early primary wound closure in the treatment of early necrotizing soft-tissue infections of the genitalia. The results showed that early closure can decrease the need for skin grafting and reduce wound convalescence time.
Article
Microbiology
Aaron C. Miller, Alan T. Arakkal, Scott H. Koeneman, Joseph E. Cavanaugh, George R. Thompson, John W. Baddley, Philip M. Polgreen
Summary: The study analyzed diagnostic delays associated with histoplasmosis using IBM Marketscan data, revealing that patients experienced multiple visits and missed opportunities for diagnosis before being diagnosed. The average delay in diagnosis was 39.5 days, with patients who had prior antibiotic use, history of other pulmonary diseases, and visited on weekends being more likely to experience delays. New diagnostic approaches for histoplasmosis are needed.
Article
Public, Environmental & Occupational Health
Jason G. Lake, Michael J. Durkin, Philip M. Polgreen, Susan E. Beekmann, Adam L. Hersh, Jason G. Newland
Summary: Pediatric antimicrobial stewardship programs (ASPs) have been found to improve antibiotic use for hospitalized children, but there is a lack of data on infectious disease physicians' opinions of ASPs. A survey was conducted to assess the perceptions of pediatric infectious disease physicians, both ASP and non-ASP, regarding ASP practices and outcomes.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Medicine, General & Internal
Aaron C. Miller, Alan T. Arakkal, Scott H. Koeneman, Joseph E. Cavanaugh, Philip M. Polgreen
Summary: This study uses machine learning approaches to mine administrative data sources and recommend conditions for consideration in studying diagnostic delays. By analyzing initial symptoms and diagnosis codes, the approach successfully identifies clinically-plausible conditions and discovers more possible diagnostic delays in tuberculosis and appendicitis.
Article
Public, Environmental & Occupational Health
Janet B. Glowicz, Emily Landon, Emily E. Sickbert-Bennett, Allison E. Aiello, Karen deKay, Karen K. Hoffmann, Lisa Maragakis, Russell N. Olmsted, Philip M. Polgreen, Polly A. Trexler, Margaret A. VanAmringe, Amber R. Wood, Deborah Yokoe, Katherine D. Ellingson
Summary: The purpose of this document is to provide practical recommendations to acute-care hospitals for preventing healthcare-associated infections through hand hygiene. It updates the previous version published in 2014 and is sponsored by the Society for Healthcare Epidemiology (SHEA) in collaboration with other organizations. This expert guidance document has major contributions from representatives of various organizations and societies.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Pharmacology & Pharmacy
Alan T. Arakkal, Linnea A. Polgreen, Cole G. Chapman, Jacob E. Simmering, Joseph E. Cavanaugh, Philip M. Polgreen, Aaron C. Miller
Summary: The presence of opioids in a household significantly increases the risk of overdose among other family members who were not prescribed an opioid. Higher levels of opioid strength and quantity are associated with increased levels of risk. Risk estimates may reflect accidental poisonings among younger family members.