Article
Virology
Fabyla D' Tacia Brito Trindade, Endrya Socorro Foro Ramos, Patricia Santos Lobo, Jedson Ferreira Cardoso, Edvaldo Tavares Penha Junior, Delana Andreza Melo Bezerra, Mayara Annanda Oliveira Neves, Jorge Alberto Azevedo Andrade, Monica Cristina Moraes Silva, Joana D'Arc Pereira Mascarenhas, Sylvia Fatima Santos Guerra, Luana Silva Soares
Summary: This study aimed to investigate the frequency and clinical features of human bocavirus (HBoV) infection in children in Acre, Northern Brazil. The results showed that HBoV infection is not always associated with acute gastroenteritis (AGE), as most infected children did not have diarrhea symptoms. Additionally, HBoV-1 was the most prevalent species detected.
Article
Microbiology
Wenjing Wang, Renzheng Guan, Ziran Liu, Feng Zhang, Rui Sun, Sitong Liu, Xiaoyan Shi, Zhilei Su, Rongxiang Liang, Kangyu Hao, Zhaoguo Wang, Xianming Liu
Summary: Persistent infection and prolonged shedding of human bocavirus 1 (HBoV1) in children have been reported, but its role as a sole causative pathogen in acute respiratory infection (ARI) is yet to be established. This study aimed to explore the pathogenicity of HBoV in ARI patients and found that HBoV1 was detected in 28.1% of the samples, with a high rate of coinfection with bacteria. Clinical characterization suggested organ function impairment and the importance of disinfection and sterilization practices. Further investigation on the interactions between HBoV and other pathogens is needed.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Immunology
Syed Moinuddin Satter, Eric Katz, Mohammad Enayet Hossain, Farzana Fariha, Muhammad Talha, Sarah L. Smart, Michael D. Bowen, Mustafizur Rahman, Umesh D. Parashar, Margaret M. Cortese
Summary: In order to examine the potential for respiratory transmission of rotavirus, this study assessed the presence of rotavirus RNA from nasal and oropharyngeal swab specimens of Bangladeshi children with acute rotavirus gastroenteritis. The findings showed that rotavirus RNA was frequently detected in stool, oral, nasal and forehead swab specimens, indicating possible respiratory transmission. This suggests the need for further investigation.
JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Multidisciplinary Sciences
Moti Iflah, Eias Kassem, Uri Rubinstein, Sophy Goren, Moshe Ephros, Dani Cohen, Khitam Muhsen
Summary: This study found that convulsions in children with AGE were associated with age, Shigella infection, rotavirus infection, body temperature, and high blood glucose levels.
SCIENTIFIC REPORTS
(2021)
Article
Virology
Kadri Koivumagi, Julia Geller, Karolin Toompere, Hiie Soeorg, Eveli Kallas, Ene-Ly Jogeda, Kristi Huik, Irja Lutsar
Summary: The study in Estonia revealed that the dominant strains of Norovirus were GII.4, GII.3, GII.17, and GII.6, with GII.4Sydney_2012[P31] being the most prevalent strain. There was a significant difference in strain diversity between age groups, indicating the importance of understanding Norovirus strain diversity for control and prevention measures.
JOURNAL OF MEDICAL VIROLOGY
(2022)
Article
Microbiology
Maria Antonia De Francesco, Giovanni Lorenzin, Antonella Meini, Richard Fabian Schumacher, Arnaldo Caruso
Summary: This study investigated the prevalence of human adenovirus infections in hospitalized pediatric patients, finding that HAdV was detected in 7.1% of stool samples with a high diversity of isolates. A majority of HAdV positives were in children under 5 years old, and genetic analysis revealed the presence of two HAdV species (B and C) with three types. This highlights the need for routine molecular assays with wide reactivity for rapid and accurate diagnosis.
MICROBIOLOGY SPECTRUM
(2021)
Article
Public, Environmental & Occupational Health
Nattika Nantachit, Pakawat Kochjan, Pattara Khamrin, Kattareeya Kumthip, Niwat Maneekarn
Summary: This study in Chiang Mai, Thailand found that HBoV infection rate in pediatric patients with acute diarrhea was 5.2%, with HBoV1 being the most predominant genotype. Phylogenetic analysis revealed that HBoV1, HBoV2, and HBoV3 were mainly related to strains from Asia.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2021)
Article
Immunology
Chimwemwe Mhango, Jonathan J. Mandolo, End Chinyama, Richard Wachepa, Oscar Kanjerwa, Chikondi Malamba-Banda, Prisca B. Matambo, Kayla G. Barnes, Chrispin Chaguza, Isaac T. Shawa, Martin M. Nyaga, Daniel Hungerford, Umesh D. Parashar, Virginia E. Pitzer, Arox W. Kamng'ona, Miren Iturriza-Gomara, Nigel A. Cunliffe, Khuzwayo C. Jere
Summary: The diversity of G and P genotypes did not change significantly after the introduction of rotavirus vaccine in Malawi, but there was an increase in P genotype diversity in children older than 12 months. G3 rotaviruses reemerged and became the predominant genotype from 2017 onwards, replacing G1P[8] and G2P[4].
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Medicine, General & Internal
Ying-Hsuan Tai, Ming-Long Chang, Pao-Hsien Chu, Chun-Chieh Yeh, Yih-Giun Cherng, Ta-Liang Chen, Chien-Chang Liao
Summary: Gastroenteritis is associated with an increased risk of acute myocardial infarction (AMI) and worse post-AMI outcomes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Virology
Dana Danino, Guy Hazan, Rofaida Mahajna, Firas Khalde, Lama Farraj, Yonat Shemer Avni, David Greenberg, Eli Hershkovitz, Yaniv Faingelernt, Noga Givon-Lavi
Summary: This study evaluated the epidemiology of viral acute gastroenteritis (AGE) and compared clinical characteristics among the five most common viruses. The results showed that rotavirus was the most prevalent virus, and despite vaccination efforts, it remained prevalent and caused more severe disease. Infections with astrovirus or sapovirus were associated with higher rates of hospital-acquired AGE and immunodeficiency, while rotavirus infections had higher rates of dehydration severity and acute kidney injury.
JOURNAL OF CLINICAL VIROLOGY
(2023)
Article
Pediatrics
Pierluigi Marzuillo, Maria Baldascino, Stefano Guarino, Silverio Perrotta, Emanuele Miraglia del Giudice, Felice Nunziata
Summary: This study aimed to evaluate the prevalence and risk factors of acute kidney injury (AKI) in children hospitalized for acute gastroenteritis (AGE). Results showed that 24.6% of patients had AKI, with longer duration of symptoms, dehydration, and lower serum bicarbonate levels being independent predictors.
PEDIATRIC NEPHROLOGY
(2021)
Article
Microbiology
Maia Metreveli, Salome Bulia, Iamze Shalamberidze, Liana Tevzadze, Shota Tsanava, Juan Cruz Goenaga, Kerstin Stingl, Paata Imnadze
Summary: This is the first study on campylobacteriosis conducted in Georgia, which revealed that it is the second most common bacterial causative agent of acute inflammatory diarrhea in hospitalized children. The study also found that campylobacteriosis primarily affects children aged 0-3 and that patients with campylobacteriosis are younger than those with shigellosis. The epidemiological pyramid with estimated magnification factors provides valuable insights into the burden of campylobacteriosis among the studied population.
Article
Microbiology
Kanti Pabbaraju, Raymond Tellier, Xiao-Li Pang, Jianling Xie, Bonita E. Lee, Linda Chui, Ran Zhuo, Otto G. Vanderkooi, Samina Ali, Phillip Tarr, Anna Funk, Stephen B. Freedman
Summary: This study aimed to characterize the etiological role of human adenovirus (HAdV) serotypes in pediatric gastroenteritis. Results showed that HAdV F40/41 serotypes accounted for the majority of cases and were almost always responsible for the symptoms, while non-F40/41 HAdV species had a higher frequency of asymptomatic infection and may not necessarily explain gastroenteritis symptoms. Real-time quantitative PCR could be useful in differentiating asymptomatic shedding from active infection.
JOURNAL OF CLINICAL MICROBIOLOGY
(2021)
Article
Pediatrics
Subal Kumar Pradhan, Sumanta Panigrahi, Pooja Sagar Padhi, Varunkumar Thiyagarajan, Saroj Kumar Satpathy
Summary: This study revealed a high prevalence of rotavirus diarrhea among hospitalized children under 5 years of age, especially during the winter season peak. The most common rotavirus genotypes were G3P[8] and G1P[8], with similar infection rates between boys and girls in children.
INDIAN JOURNAL OF PEDIATRICS
(2021)
Article
Microbiology
Ran Zhuo, Xiaofeng Ding, Stephen B. Freedman, Bonita E. Lee, Samina Ali, Jasper Luong, Jianling Xie, Linda Chui, Ying Wu, Xiaoli Pang
Summary: Sapovirus is a common cause of acute gastroenteritis in children with high genetic diversity. The virus can be detected year-round, with peak seasons during the winter months. There were no significant differences in the severity of gastroenteritis by genogroup or genotype.
JOURNAL OF CLINICAL MICROBIOLOGY
(2021)