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Type 2 Diabetes: A Protective Factor for Prostate Cancer? An Overview of Proposed Mechanisms

期刊

CLINICAL GENITOURINARY CANCER
卷 12, 期 3, 页码 143-148

出版社

CIG MEDIA GROUP, LP
DOI: 10.1016/j.clgc.2014.01.001

关键词

CXCL14; Insulin; Insulin-like growth factor-1; Metformin; Testosterone

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Diabetes mellitus and prostate cancer are 2 of the most important public health concerns, especially in the elderly population. Although diabetes has been recognized as a potent risk factor for many types of cancers, there is a large amount of evidence that shows that it has a protective role against prostate cancer. The underlying cause of this protective role is not fully understood, however, some mechanisms have been proposed in this area. In the present study we have reviewed these mechanisms and some new mechanisms are also proposed.

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