Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Chenxi Wu, Lance T. Hall, David C. Brandon
Summary: An 82-year-old man underwent outpatient nuclear medicine gastric-emptying scintigraphy for dysphagia and regurgitation. The scintigraphy showed delayed gastric emptying but subsequent CT scan and upper gastrointestinal fluoroscopy revealed normal stomach size and function, with an enormously dilated esophagus indicating achalasia. It is important to pay attention to the location and shape of the visualized stomach and recognize that a significantly dilated esophagus can mimic an elongated stomach during scintigraphy.
CLINICAL NUCLEAR MEDICINE
(2022)
Article
Gastroenterology & Hepatology
Hina Shah, Reethy Sundar, David E. Arboleda Prado, Jian W. Dong, David Z. Chow, Braden Kuo, Stephan D. Voss, Heather A. Jacene, Matthew S. Robertson, Thomas S. C. Ng
Summary: The study aimed to determine the appropriateness of current gastric emptying scintigraphy criteria in clinical practice and its relevance for partially ingested meals. The results showed that the current standards for gastric emptying scintigraphy in adults can differentiate between normal and delayed populations and can be applied to partially ingested meals with at least 50% completion.
DIGESTIVE DISEASES AND SCIENCES
(2023)
Article
Endocrinology & Metabolism
Simon Veedfald, Jens F. Rehfeld, Gerrit van Hall, Lars B. Svendsen, Jens J. Holst
Summary: The study investigated the rapid entero-pancreatic hormone secretion after nutrient ingestion and its correlation with gastric emptying and glucose absorption. Findings showed characteristic differences in timing and amplitude of early postprandial hormone responses, emphasizing the need to consider individual variations when interpreting mean responses and designing study protocols.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Biochemical Research Methods
Aaron M. Lett, Alexandra Lim, Charlotte Skinner, James Maurice, Nikhil Vergis, Ara Darzi, Robert Goldin, Mark Thursz, Alex J. Thompson
Summary: The transcutaneous fluorescence spectroscopy technique provides a fast, non-invasive, and sample-free method for assessing gastric emptying rate (GER) clinically. Comparison with the paracetamol absorption test showed good agreement, indicating the potential of this new approach for GER assessment.
BIOMEDICAL OPTICS EXPRESS
(2021)
Article
Gastroenterology & Hepatology
I-Hsuan Huang, Jolien Schol, Florencia Carbone, Yaozhu J. Chen, Karen Van den Houte, Lukas Michaja Balsiger, Bert Broeders, Tim Vanuytsel, Jan Tack
Summary: This study investigated the symptom patterns in distinguishing gastroparesis from functional dyspepsia. The results showed that patients with gastroparesis-like symptoms had a higher prevalence of delayed gastric emptying and higher symptom severity compared to patients with FD symptoms.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Endocrinology & Metabolism
Daniel Gonzalez-Izundegui, Alejandro Campos, Gerardo Calderon, Maria L. Ricardo-Silgado, Lizeth Cifuentes, Paul A. Decker, Eric J. Vargas, Linh Tran, Duane Burton, Barham Abu Dayyeh, Michael Camilleri, Jeanette E. Eckel-Passow, Andres Acosta
Summary: This study found an association between gastric emptying and sensations of appetite, with rapid gastric emptying being linked to increased appetite, which could contribute to weight gain.
Review
Gastroenterology & Hepatology
Jutta Keller, Heinz F. Hammer, Bruno Hauser
Summary: C-13-gastric emptying breath tests are validated, reliable, and non-invasive tools for measuring gastric emptying velocity, but test results are influenced by various factors.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Multidisciplinary Sciences
Kamal Albarazanji, Andrea R. Nawrocki, Bin Gao, Xiaoli Wang, Yixin (Jim) Wang, Yong-Fu Xiao
Summary: Meal ingestion elicits various responses in different individuals, and the mixed meal tolerance test is a valuable method for evaluating pancreatic beta-cell reserve and glucose homeostasis. Nonhuman primates are a useful model for studying diabetes, and the reproducibility of responses to mixed meal administration in obese monkeys is demonstrated in this study.
SCIENTIFIC REPORTS
(2021)
Article
Fisheries
Hung Quang Tran, Mikko Kiljunen, Hien Van Doan, Vlastimil Stejskal
Summary: Stable isotope analysis and Bayesian mixing models were used to study the effects of feed components on the development of European perch tissues. Moderate inclusion of yellow mealworm larvae meal was found to promote tissue growth, while higher levels may decrease its contribution, with soy-derived ingredients also playing a significant role in tissue development.
Article
Gastroenterology & Hepatology
Michael Camilleri, Ting Zheng, Kia Vosoughi, Camille Lupianez-Merly, Deborah Eckert, Irene Busciglio, Duane Burton, Saam Dilmaghani
Summary: Objective symptoms of gastroparesis and functional dyspepsia overlap, and using egg protein substitute to measure gastric emptying can help reclassify patients. This study assessed the inter-individual and intra-individual coefficients of variation in gastric emptying in symptomatic patients with gastroparesis or functional dyspepsia. The results suggest that the 320 kcal (30% fat) gastric emptying scintigraphic test provides consistent diagnoses in the majority of patients.
Article
Gastroenterology & Hepatology
Richard McCallum, Carola La Follette, Alok Kumar Dwivedi, Irene Sarosiek, Anna Havey, Jesus Diaz
Summary: This study established thresholds for late-onset rapid gastric emptying (LRGE) and found that 5% of patients classified as normal actually had abnormal gastric emptying patterns. LRGE patients exhibited symptoms such as abdominal pain, bloating, nausea, or diarrhea starting more than 1 hour postprandial.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Gastroenterology & Hepatology
Alan H. Maurer, Daohai Yu, Xiaoning Lu, Simindokht Dadparvar, Bhishak H. Kamat, Dariush Shahsavari, Henry P. Parkman
Summary: In this study involving 363 patients, delayed small bowel transit (SBT) was found in 19.3% of patients undergoing GES/SBTS. Common symptoms associated with delayed SBT include postprandial fullness, stomach fullness, nausea, and bloating. Symptom assessment revealed that delayed SBT is often linked with delayed gastric emptying, but early satiety is more associated with delayed gastric emptying while bloating is more associated with delayed SBT.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Gastroenterology & Hepatology
Danielle K. Orsagh-Yentis, Shasha Bai, Adam Bobbey, Caitlin Hayes, Antoinette Pusateri, Kent Williams
Summary: The study successfully conducted a C-13-Spirulina platensis GEBT in healthy children, finding that females had a slower rate of gastric emptying than males and children with a higher BMI had slower rates compared to normally weighted children. Additionally, children aged 6-9 had a later time to reach maximum gastric emptying rate compared to older children. The agreement between scintigraphic and GEBT measurements was moderate.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Endocrinology & Metabolism
Lea Aigner, Bjoern Becker, Sonja Gerken, Daniel R. Quast, Juris J. Meier, Michael A. Nauck
Summary: The study found that day-to-day variations in fasting plasma glucose do not significantly affect gastric emptying in patients with type 1 diabetes; on the contrary, chronic hyperglycemia is associated with slowed gastric emptying. This contrasts with the impact of rapid glucose fluctuations on gastric emptying.
Article
Gastroenterology & Hepatology
Alexandra C. Barrett, Kathleen P. Johnson, Maan El Halabi, Henry P. Parkman
Summary: This study explores the meal-eating characteristics of patients with Gp symptoms and their relationship with the severity of gastric emptying delay. The findings suggest that patients modify their diets more as the severity of gastric retention worsens. Understanding these meal-eating characteristics is crucial for symptom management and dietary education for Gp patients.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)