Randomized Controlled Study of the Safety and Immunogenicity of Pneumococcal Vaccine Formulations Containing PhtD and Detoxified Pneumolysin with Alum or Adjuvant System AS02Vin Elderly Adults

Adjuvant system AS02V enhances humoral and cellular immune responses to pneumococcal protein PhtD vaccine in healthy young and older adults: Randomised, controlled trials

(2015) Isabel Leroux-Roels et al.   VACCINE

Safety, Immunogenicity, and Antibody Persistence following an Investigational Streptococcus pneumoniae and Haemophilus influenzae Triple-Protein Vaccine in a Phase 1 Randomized Controlled Study in Healthy Adults

(2013) Johan Berglund et al.   Clinical and Vaccine Immunology

Preventing Pneumococcal Disease in the Elderly

(2013) Angel Vila-Corcoles et al.   DRUGS & AGING

Mini-Review: Novel Therapeutic Strategies to Blunt Actions of Pneumolysin in the Lungs

(2013) Rudolf Lucas et al.   Toxins

Editorial Commentary: Should 13-Valent Protein-Conjugate Pneumococcal Vaccine Be Used Routinely in Adults?

(2012) D. M. Musher   CLINICAL INFECTIOUS DISEASES

Epidemiology of Invasive Pneumococcal Disease Among High-Risk Adults Since the Introduction of Pneumococcal Conjugate Vaccine for Children

(2012) R. D. Muhammad et al.   CLINICAL INFECTIOUS DISEASES

Neutralizing Antibodies Elicited by a Novel Detoxified Pneumolysin Derivative, PlyD1, Provide Protection against Both Pneumococcal Infection and Lung Injury

(2012) Danielle Salha et al.   INFECTION AND IMMUNITY

Aging Population and Future Burden of Pneumococcal Pneumonia in the United States

(2012) Peter C. Wroe et al.   JOURNAL OF INFECTIOUS DISEASES

Pneumococcal Conjugate and Plain Polysaccharide Vaccines Have Divergent Effects on Antigen-Specific B Cells

(2012) Elizabeth A. Clutterbuck et al.   JOURNAL OF INFECTIOUS DISEASES

Serotype-independent pneumococcal experimental vaccines that induce cellular as well as humoral immunity

(2012) R. Malley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polyhistidine triad proteins of pathogenic streptococci

(2012) Charles D. Plumptre et al.   TRENDS IN MICROBIOLOGY

Vaccine candidates PhtD and PhtE of Streptococcus pneumoniae are adhesins that elicit functional antibodies in humans

(2012) M. Nadeem Khan et al.   VACCINE

Safety and immunogenicity of the pneumococcal pneumolysin derivative PlyD1 in a single-antigen protein vaccine candidate in adults

(2012) Thierry Kamtchoua et al.   VACCINE

Next generation pneumococcal vaccines

(2011) Kristin L Moffitt et al.   CURRENT OPINION IN IMMUNOLOGY

Recent clinical experience with vaccines using MPL- and QS-21-containing Adjuvant Systems

(2011) Nathalie Garçon et al.   Expert Review of Vaccines

A protein-based pneumococcal vaccine protects rhesus macaques from pneumonia after experimental infection with Streptococcus pneumoniae

(2011) Philippe Denoël et al.   VACCINE

Preclinical Evaluation of the Pht Proteins as Potential Cross-Protective Pneumococcal Vaccine Antigens

(2010) Fabrice Godfroid et al.   INFECTION AND IMMUNITY

Antibody and cell-mediated immunity to Streptococcus pneumoniae: implications for vaccine development

(2010) Richard Malley   JOURNAL OF MOLECULAR MEDICINE-JMM

Clinical and economic burden of community-acquired pneumonia among adults in Europe

(2010) T Welte et al.   THORAX

Efficacy of pneumococcal vaccination in adults: a meta-analysis

(2009) A. Huss et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Pneumolysin: A Double-Edged Sword During the Host-Pathogen Interaction

(2008) Helen Marriott et al.   CURRENT MOLECULAR MEDICINE

Vaccine Adjuvant Systems containing monophosphoryl lipid A and QS21 induce strong and persistent humoral and T cell responses against hepatitis B surface antigen in healthy adult volunteers

(2008) Pierre Vandepapelière et al.   VACCINE