期刊
CLINICAL AND VACCINE IMMUNOLOGY
卷 21, 期 2, 页码 250-252出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/CVI.00632-13
关键词
-
资金
- Channel 7 Children's Research Foundation [13699]
- Australian National Health and Medical Research Council [1023781, 1040830, 1024175, 1020561, 1034703, 545216]
Nontypeable Haemophilus influenzae (NTHi)-associated disease is a major health problem globally. Whole-genome sequence analysis identified the absence of hpd genes encoding Haemophilus protein D in 3 of 16 phylogenetically distinct NTHi isolates. This novel finding is of potential clinical significance, as protein D and hpd represent important NTHi vaccine antigen and diagnostic targets, respectively.
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