Sublingual Administration of an Adenovirus Serotype 5 (Ad5)-Based Vaccine Confirms Toll-Like Receptor Agonist Activity in the Oral Cavity and Elicits Improved Mucosal and Systemic Cell-Mediated Responses against HIV Antigens despite Preexisting Ad5 Immunity

Adenovirus Vector-Induced Innate Inflammatory Mediators, MAPK Signaling, As Well As Adaptive Immune Responses Are Dependent upon Both TLR2 and TLR9 In Vivo

(2014) D. M. Appledorn et al.   JOURNAL OF IMMUNOLOGY

A New Adenovirus Based Vaccine Vector Expressing an Eimeria tenella Derived TLR Agonist Improves Cellular Immune Responses to an Antigenic Target

(2010) Daniel M. Appledorn et al.   PLoS One

Lessons learned from natural infection: focusing on the design of protective T cell vaccines for HIV/AIDS

(2010) Jeffrey D. Ahlers et al.   TRENDS IN IMMUNOLOGY

Overcoming pre-existing adenovirus immunity by genetic engineering of adenovirus-based vectors

(2009) Sergey S Seregin et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

CCR7-CCL19/CCL21-Regulated Dendritic Cells Are Responsible for Effectiveness of Sublingual Vaccination

(2009) J.-H. Song et al.   JOURNAL OF IMMUNOLOGY

Sublingual Immunization with Nonreplicating Antigens Induces Antibody-Forming Cells and Cytotoxic T Cells in the Female Genital Tract Mucosa and Protects against Genital Papillomavirus Infection

(2009) N. Cuburu et al.   JOURNAL OF IMMUNOLOGY

TRIF, and TRIF-Interacting TLRs Differentially Modulate Several Adenovirus Vector-Induced Immune Responses

(2009) D.M. Appledorn et al.   Journal of Innate Immunity

Viruses as vaccine vectors for infectious diseases and cancer

(2009) Simon J. Draper et al.   NATURE REVIEWS MICROBIOLOGY

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET

Sublingual Immunotherapy

(2008) Anthony J. Frew   NEW ENGLAND JOURNAL OF MEDICINE

Nasal Delivery of an Adenovirus-Based Vaccine Bypasses Pre-Existing Immunity to the Vaccine Carrier and Improves the Immune Response in Mice

(2008) Maria A. Croyle et al.   PLoS One

Sublingual vaccination with influenza virus protects mice against lethal viral infection

(2008) J.-H. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional CD8+ CTLs in mucosal sites and HIV infection: moving forward toward a mucosal AIDS vaccine

(2008) Igor M. Belyakov et al.   TRENDS IN IMMUNOLOGY

Mucosa and vaccine-induced immune protection in nonhuman primates

(2008) Joseph J Mattapallil et al.   Current Opinion in HIV and AIDS