Rapid-onset clinical and mechanistic effects of anti-C5aR treatment in the mouse collagen-induced arthritis model

Monoclonal antibody treatments for rheumatoid arthritis

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Inflammatory Responses Induced by Lipopolysaccharide Are Amplified in Primary Human Monocytes but Suppressed in Macrophages by Complement Protein C5a

(2013) V. Seow et al.   JOURNAL OF IMMUNOLOGY

Complement in the immunopathogenesis of rheumatic disease

(2012) Gunnar Sturfelt et al.   Nature Reviews Rheumatology

Baseline serum MMP-3 levels in patients with Rheumatoid Arthritis are still independently predictive of radiographic progression in a longitudinal observational cohort at 8 years follow up

(2012) Mark Houseman et al.   ARTHRITIS RESEARCH & THERAPY

Complement Activation Triggers Metalloproteinases Release Inducing Cervical Remodeling and Preterm Birth in Mice

(2011) Juan M. Gonzalez et al.   AMERICAN JOURNAL OF PATHOLOGY

The new face of anaphylatoxins in immune regulation

(2011) Wuding Zhou   IMMUNOBIOLOGY

Complement C3a and C5a modulate osteoclast formation and inflammatory response of osteoblasts in synergism with IL-1β

(2011) Anita Ignatius et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Role of C3a Receptors, C5a Receptors, and Complement Protein C6 Deficiency in Collagen Antibody-Induced Arthritis in Mice

(2011) N. K. Banda et al.   JOURNAL OF IMMUNOLOGY

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting chemokine receptors in chronic inflammatory diseases: An extensive review

(2011) Pim J. Koelink et al.   PHARMACOLOGY & THERAPEUTICS

Smoking, citrullination and genetic variability in the immunopathogenesis of rheumatoid arthritis

(2011) Lars Klareskog et al.   SEMINARS IN IMMUNOLOGY

Evaluation of therapeutic targets in animal models of arthritis: How does it relate to rheumatoid arthritis?

(2010) Lisette Bevaart et al.   ARTHRITIS AND RHEUMATISM

Macrophage migration inhibitory factor regulates neutrophil chemotactic responses in inflammatory arthritis in mice

(2010) Leilani L. Santos et al.   ARTHRITIS AND RHEUMATISM

Efficient osteoclast differentiation requires local complement activation

(2010) Z. Tu et al.   BLOOD

Complement drives Th17 cell differentiation and triggers autoimmune arthritis

(2010) Motomu Hashimoto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Recombinant Vaccine Effectively Induces C5a-Specific Neutralizing Antibodies and Prevents Arthritis

(2010) Kutty Selva Nandakumar et al.   PLoS One

Receptors for complement C5a. The importance of C5aR and the enigmatic role of C5L2

(2008) Hyun Lee et al.   IMMUNOLOGY AND CELL BIOLOGY