Human mesenchymal stem cells suppress donor CD4+T cell proliferation and reduce pathology in a humanized mouse model of acute graft-versus-host disease

Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study

(2012) Peter Connick et al.   LANCET NEUROLOGY

Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's disease

(2011) R. Ciccocioppo et al.   GUT

Allogeneic mesenchymal stem cells prevent allergic airway inflammation by inducing murine regulatory T cells

(2010) H. Kavanagh et al.   ALLERGY

Mesenchymal stromal cells inhibit graft-versus-host disease of mice in a dose-dependent manner

(2010) Sun-Young Joo et al.   CYTOTHERAPY

Human umbilical cord blood-derived stromal cells prevent graft-versus-host disease in mice following haplo-identical stem cell transplantation

(2010) Lei Hao et al.   CYTOTHERAPY

Mesenchymal stromal cells transiently alter the inflammatory milieu post-transplant to delay graft-versus-host disease

(2010) M. E. Christensen et al.   HAEMATOLOGICA

Decrease of CD4+CD25+ regulatory T cells and TGF-β at early immune reconstitution is associated to the onset and severity of graft-versus-host disease following allogeneic haematogenesis stem cell transplantation

(2010) Qing Li et al.   LEUKEMIA RESEARCH

Adult Human Mesenchymal Stem Cells Added to Corticosteroid Therapy for the Treatment of Acute Graft-versus-Host Disease

(2009) Partow Kebriaei et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Ex vivo expanded human CD4+CD25+Foxp3+ regulatory T cells prevent lethal xenogenic graft versus host disease (GVHD)

(2009) Tinghua Cao et al.   CELLULAR IMMUNOLOGY

Xenoreactivity of human clonal mesenchymal stem cells in a major histocompatibility complex-matched allogeneic graft-versus-host disease mouse model

(2009) Myung-Shin Jeon et al.   CELLULAR IMMUNOLOGY

Cell contact, prostaglandin E2and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25Highforkhead box P3+regulatory T cells

(2009) K. English et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Graft-versus-host disease

(2009) James LM Ferrara et al.   LANCET

Repair of Tissues by Adult Stem/Progenitor Cells (MSCs): Controversies, Myths, and Changing Paradigms

(2009) Darwin J Prockop   MOLECULAR THERAPY

Genzyme backs Osiris, despite Prochymal flop

(2009) Malorye Allison   NATURE BIOTECHNOLOGY

Prevention and treatment of acute GvHD

(2008) C Messina et al.   BONE MARROW TRANSPLANTATION

A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs

(2008) Mihaela Crisan et al.   Cell Stem Cell

IFN-γ activation of mesenchymal stem cells for treatment and prevention of graft versus host disease

(2008) David Polchert et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

(2008) Katarina Le Blanc et al.   LANCET

Murine mesenchymal stem cells suppress dendritic cell migration, maturation and antigen presentation

(2007) Karen English et al.   IMMUNOLOGY LETTERS

Human Leukocyte Antigen-G5 Secretion by Human Mesenchymal Stem Cells Is Required to Suppress T Lymphocyte and Natural Killer Function and to Induce CD4+CD25highFOXP3+Regulatory T Cells

(2007) Zohair Selmani et al.   STEM CELLS