Effects of combination therapy with dipeptidyl peptidase-IV and histone deacetylase inhibitors in the non-obese diabetic mouse model of type 1 diabetes

Inhibition of Histone Deacetylase 3 Protects Beta Cells from Cytokine-Induced Apoptosis

(2012) Danny Hung-Chieh Chou et al.   CHEMISTRY & BIOLOGY

Targeting Regulatory T Cells in the Treatment of Type 1 Diabetes Mellitus

(2012) S.M. Cabrera et al.   CURRENT MOLECULAR MEDICINE

Islet  -Cell Endoplasmic Reticulum Stress Precedes the Onset of Type 1 Diabetes in the Nonobese Diabetic Mouse Model

(2012) S. A. Tersey et al.   DIABETES

Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children

(2012) M. Lundh et al.   DIABETOLOGIA

The DPP4 inhibitor linagliptin delays the onset of diabetes and preserves β-cell mass in non-obese diabetic mice

(2012) Jacob Jelsing et al.   JOURNAL OF ENDOCRINOLOGY

How Does Type 1 Diabetes Develop?: The Notion of Homicide or  -Cell Suicide Revisited

(2011) M. A. Atkinson et al.   DIABETES

Effect of sitagliptin on glucose control in adult patients with Type 1 diabetes: a pilot, double-blind, randomized, crossover trial

(2011) S. L. Ellis et al.   DIABETIC MEDICINE

Chromatin remodeling resets the immune system to protect against autoimmune diabetes in mice

(2011) Tejas Patel et al.   IMMUNOLOGY AND CELL BIOLOGY

Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial

(2011) Diane K Wherrett et al.   LANCET

Teplizumab for treatment of type 1 diabetes (Protégé study): 1-year results from a randomised, placebo-controlled trial

(2011) Nicole Sherry et al.   LANCET

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(2011) Eli Lewis et al.   MOLECULAR MEDICINE

Rapamycin prevents the onset of insulin-dependent diabetes mellitus (IDDM) in NOD mice

(2010) W. L. BAEDER et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Reversal of New-Onset Diabetes through Modulating Inflammation and Stimulating β-Cell Replication in Nonobese Diabetic Mice by a Dipeptidyl Peptidase IV Inhibitor

(2010) Lei Tian et al.   ENDOCRINOLOGY

Inhibition of Deoxyhypusine Synthase Enhances Islet β Cell Function and Survival in the Setting of Endoplasmic Reticulum Stress and Type 2 Diabetes

(2010) Reiesha D. Robbins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxisome Proliferator-Activated Receptor   Activation Restores Islet Function in Diabetic Mice through Reduction of Endoplasmic Reticulum Stress and Maintenance of Euchromatin Structure

(2009) C. Evans-Molina et al.   MOLECULAR AND CELLULAR BIOLOGY

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

(2009) Mark D. Pescovitz et al.   NEW ENGLAND JOURNAL OF MEDICINE

The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunity in NZB/W F1 mice

(2008) Christopher M. Reilly et al.   JOURNAL OF AUTOIMMUNITY