Evidence for the innate immune response as a correlate of protection in human immunodeficiency virus (HIV)-1 highly exposed seronegative subjects (HESN)

HIV-1 exposed uninfected men who have sex with men have increased levels of salivary CC-chemokines associated with sexual behavior

(2010) Klara Hasselrot et al.   AIDS

HIV viral set point and host immune control in individuals with HIV-specific CD8+ T-cell responses prior to HIV acquisition

(2010) Rupert Kaul et al.   AIDS

Phenotypically and functionally distinct subsets contribute to the expansion of CD56−/CD16+ natural killer cells in HIV infection

(2010) Henoch S Hong et al.   AIDS

Increased plasmacytoid dendritic cell maturation and natural killer cell activation in HIV-1 exposed, uninfected intravenous drug users

(2010) Costin Tomescu et al.   AIDS

Induction of systemic HIV-1-specific cellular immune responses by oral exposure in the uninfected partner of discordant couples

(2010) Carina L Pérez et al.   AIDS

Scarcity or Absence of Humoral Immune Responses in the Plasma and Cervicovaginal Lavage Fluids of Heavily HIV-1-Exposed But Persistently Seronegative Women

(2010) Jiri Mestecky et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

TLR Activation Pathways in HIV-1–Exposed Seronegative Individuals

(2010) Mara Biasin et al.   JOURNAL OF IMMUNOLOGY

Low-Level Exposure to HIV Induces Virus-Specific T Cell Responses and Immune Activation in Exposed HIV-Seronegative Individuals

(2010) C. Restrepo et al.   JOURNAL OF IMMUNOLOGY

Cohorts for the Study of HIV‐1–Exposed but Uninfected Individuals: Benefits and Limitations

(2010) R. E. Horton et al.   JOURNAL OF INFECTIOUS DISEASES

Innate Immunity in Resistance to HIV Infection

(2010) Mara Biasin et al.   JOURNAL OF INFECTIOUS DISEASES

Lack of Detectable HIV-1–Specific CD8+ T Cell Responses in Zambian HIV-1–Exposed Seronegative Partners of HIV-1–Positive Individuals

(2010) Marylyn M. Addo et al.   JOURNAL OF INFECTIOUS DISEASES

Pathologic natural killer cell subset redistribution in HIV-1 infection: new insights in pathophysiology and clinical outcomes

(2010) Enrico Brunetta et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Natural Suppression of Human Immunodeficiency Virus Type 1 Replication Is Mediated by Transitional Memory CD8+ T Cells

(2010) M. S. Killian et al.   JOURNAL OF VIROLOGY

Low-Dose Mucosal Simian Immunodeficiency Virus Infection Restricts Early Replication Kinetics and Transmitted Virus Variants in Rhesus Monkeys

(2010) J. Liu et al.   JOURNAL OF VIROLOGY

Increased α-Defensins 1-3 Production by Dendritic Cells in HIV-Infected Individuals Is Associated with Slower Disease Progression

(2010) Marta Rodríguez-García et al.   PLoS One

BST-2/tetherin: a new component of the innate immune response to enveloped viruses

(2010) David T. Evans et al.   TRENDS IN MICROBIOLOGY

Elevation of Intact and Proteolytic Fragments of Acute Phase Proteins Constitutes the Earliest Systemic Antiviral Response in HIV-1 Infection

(2010) Holger B. Kramer et al.   PLoS Pathogens

A combined genotype of KIR3DL1 high expressing alleles and HLA-B*57 is associated with a reduced risk of HIV infection

(2009) Salix Boulet et al.   AIDS

Increased proportion of KIR3DS1 homozygotes in HIV-exposed uninfected individuals

(2009) Salix Boulet et al.   AIDS

HIV-neutralizing immunoglobulin A and HIV-specific proliferation are independently associated with reduced HIV acquisition in Kenyan sex workers

(2009) Taha Hirbod et al.   AIDS

Oral HIV-exposure elicits mucosal HIV-neutralizing antibodies in uninfected men who have sex with men

(2009) Klara Hasselrot et al.   AIDS

Elevated elafin/trappin-2 in the female genital tract is associated with protection against HIV acquisition

(2009) Shehzad M Iqbal et al.   AIDS

Levels of innate immune factors in genital fluids: association of alpha defensins and LL-37 with genital infections and increased HIV acquisition

(2009) Pauline Levinson et al.   AIDS

Antiviral Activity of the Interferon-Induced Cellular Protein BST-2/Tetherin

(2009) Andrey Tokarev et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

The decreased expression of Siglec-7 represents an early marker of dysfunctional natural killer-cell subsets associated with high levels of HIV-1 viremia

(2009) E. Brunetta et al.   BLOOD

Cutting Edge: Unusual NK Cell Responses to HIV-1 Peptides Are Associated with Protection against Maternal-Infant Transmission of HIV-1

(2009) Caroline T. Tiemessen et al.   JOURNAL OF IMMUNOLOGY

Circulating Monocytes in HIV-1-Infected Viremic Subjects Exhibit an Antiapoptosis Gene Signature and Virus- and Host-Mediated Apoptosis Resistance

(2009) M. S. Giri et al.   JOURNAL OF IMMUNOLOGY

Retention of viability, cytotoxicity, and response to IL-2, IL-15, or IFN-α by human NK cells after CD107a degranulation

(2009) Costin Tomescu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Role of Natural Killer Cells in a Cohort of Elite Suppressors: Low Frequency of the Protective KIR3DS1 Allele and Limited Inhibition of Human Immunodeficiency Virus Type 1 Replication In Vitro

(2009) K. A. O'Connell et al.   JOURNAL OF VIROLOGY

Preinfection Human Immunodeficiency Virus (HIV)-Specific Cytotoxic T Lymphocytes Failed To Prevent HIV Type 1 Infection from Strains Genetically Unrelated to Viruses in Long-Term Exposed Partners

(2009) Y. Liu et al.   JOURNAL OF VIROLOGY

Induction of a Striking Systemic Cytokine Cascade prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections

(2009) A. R. Stacey et al.   JOURNAL OF VIROLOGY

HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4+ cell infection: an IgA gene and functional analysis

(2009) D Tudor et al.   Mucosal Immunology

Glycerol monolaurate prevents mucosal SIV transmission

(2009) Qingsheng Li et al.   NATURE

Associations of human leukocyte antigen DRB with resistance or susceptibility to HIV-1 infection in the Pumwani Sex Worker Cohort

(2008) Philip A Lacap et al.   AIDS

The ‘immunologic advantage’ of HIV-exposed seronegative individuals

(2008) Masaaki Miyazawa et al.   AIDS

Cervical HIV-Specific IgA in a Population of Commercial Sex Workers Correlates with Repeated Exposure But Not Resistance to HIV

(2008) Rachel E. Horton et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Salivary human immunodeficiency virus (HIV)-1-specific immunoglobulin A in HIV-1-exposed infants in Kenya

(2008) C. Farquhar et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Potentially Exposed but Uninfected Individuals Produce Cytotoxic and Polyfunctional Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses Which Can Be Defined to the Epitope Level

(2008) A. L. Erickson et al.   Clinical and Vaccine Immunology

Increased Levels of Human Beta-Defensins mRNA in Sexually HIV-1 Exposed But Uninfected Individuals

(2008) Wildeman Zapata et al.   CURRENT HIV RESEARCH

The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?

(2008) Rafick-Pierre Sekaly   JOURNAL OF EXPERIMENTAL MEDICINE

Conferral of Enhanced Natural Killer Cell Function by KIR3DS1 in Early Human Immunodeficiency Virus Type 1 Infection

(2008) B. R. Long et al.   JOURNAL OF VIROLOGY

HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case–cohort analysis

(2008) M Juliana McElrath et al.   LANCET

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET

Not just sheer luck! Immune correlates of protection against HIV-1 infection

(2007) Luca Piacentini et al.   VACCINE