4.6 Article

Individual Assessment of Inherent Arterial Stiffness Using Nomogram and Pulse Wave Velocity Index: The Ohasama Study

期刊

CLINICAL AND EXPERIMENTAL HYPERTENSION
卷 33, 期 3, 页码 147-152

出版社

TAYLOR & FRANCIS INC
DOI: 10.3109/10641963.2010.531839

关键词

arterial stiffness; pulse wave velocity; nomogram

资金

  1. Ministry of Education, Culture, Sports, Science, and Technology, Japan [15790293, 16590433, 17790381, 18390192, 18590587, 19590929, 19790423]
  2. Ministry of Health, Labor and Welfare, Health and Labor Sciences Research Grants, Japan [H17-Kenkou-007, H18-Junkankitou [Seishuu]-Ippan-012, H20-Junkankitou [Seishuu]-Ippan-009, H20-Junkankitou [Seishuu]-Ippan-013]
  3. Promotion of Science (JSPS), Tokyo, Japan [16.54041, 18.54042, 19.7152, 20.7198, 20.7477, 20.54043]
  4. Ministry of Health, Labor and Welfare, Japan
  5. Japan Atherosclerosis Prevention Fund
  6. Uehara Memorial Foundation
  7. Takeda Medical Research Foundation
  8. National Cardiovascular Research Grants
  9. Biomedical Innovation Grants

向作者/读者索取更多资源

We measured the brachial-ankle pulse wave velocity (baPWV) in 491 normotensives and determined the PWV index (measured baPWV-theoretical baPWV) in 491 normotensives and 83 controlled hypertensives. Linear regression analysis revealed that the theoretical baPWV (cm/sec) was 0.21 x age(2) (years(2))-13.73 x age (years) + 0.05 x mean arterial pressure(2) (mmHg(2)) + 3.95 x heart rate (bpm) + 36.49 x gender (1 male; 0 female) + 733 (R-2 = 0.53). The calculated PWV index was significantly higher in 13 smokers than 70 nonsmokers among controlled hypertensives. The calculated PWV index might provide more precise information about inherent arterial stiffness.

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