期刊
CLINICAL AND EXPERIMENTAL HYPERTENSION
卷 31, 期 8, 页码 705-712出版社
TAYLOR & FRANCIS INC
DOI: 10.3109/10641960903254422
关键词
short sleep; hypertension; young adults; ambulatory blood pressure monitoring; cardiac sympathovagal balance
Variation in 24-h blood pressure (BP) is associated with multiple factors, but the association has not been thoroughly examined in young adults. To elucidate the potential factors associated with variation in 24-h BP, 331 healthy medical students were investigated. Awake mean BP negatively correlated with sleep duration in males. Sixty-seven subjects (20.2%) had a high 24-h BP according to the ESH/ESC 2007 guidelines (systolic blood pressure (SBP) > 125 and/or diastolic blood pressure (DBP) > 80 mmHg). After multivariate analysis for confounding factors, male gender, body mass index (HMI),smoking, the 24-h low/high frequency component (heart rate variability Spectral analysis), and short sleep (5 h or less) were found to be associated with high BP. The present study is the first to demonstrate the multivariate risk factors for elevated 24-h BP in a large number of young adults. Further investigation is required to determine the causal relationship between modifiable BP-related factors and elevated 24-h BP in young adults.
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