Mapping of TLR5 and TLR7 in central and distal human airways and identification of reduced TLR expression in severe asthma

Microbes and mucosal immune responses in asthma

(2013) Trevor T Hansel et al.   LANCET

Viral and bacterial infection in acute asthma and chronic obstructive pulmonary disease increases the risk of readmission

(2013) Peter A.B. Wark et al.   RESPIROLOGY

Mechanism of Action of Inhibition of Allergic Immune Responses by a Novel Antedrug TLR7 Agonist

(2012) H. Matsui et al.   JOURNAL OF IMMUNOLOGY

Altered regulation of Toll-like receptor responses impairs antibacterial immunity in the allergic lung

(2012) M Habibzay et al.   Mucosal Immunology

Viral infections and atopy in asthma pathogenesis: new rationales for asthma prevention and treatment

(2012) Patrick G Holt et al.   NATURE MEDICINE

The Toll-like receptor 5 ligand flagellin promotes asthma by priming allergic responses to indoor allergens

(2012) Rhonda H Wilson et al.   NATURE MEDICINE

Asthma phenotypes: the evolution from clinical to molecular approaches

(2012) Sally E Wenzel   NATURE MEDICINE

The airway epithelium in asthma

(2012) Bart N Lambrecht et al.   NATURE MEDICINE

The Role of Alveolar Epithelial Cells in Initiating and Shaping Pulmonary Immune Responses: Communication between Innate and Adaptive Immune Systems

(2012) Olga D. Chuquimia et al.   PLoS One

Toll-like receptor 5 (TLR5), IL-1  secretion, and asparagine endopeptidase are critical factors for alveolar macrophage phagocytosis and bacterial killing

(2012) D. Descamps et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repeated intranasal TLR7 stimulation reduces allergen responsiveness in allergic rhinitis

(2012) Lennart Greiff et al.   RESPIRATORY RESEARCH

Upping the antedrug: is a novel anti-inflammatory Toll-like receptor 7 agonist also a bronchodilator?

(2011) EH Kaufman et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activation of the PI3K pathway increases TLR-induced TNF-α and IL-6 but reduces IL-1β production in mast cells

(2011) Thomas Hochdörfer et al.   CELLULAR SIGNALLING

Regulation of the Antimicrobial Response by NLR Proteins

(2011) Eran Elinav et al.   IMMUNITY

Toll like receptors in diseases of the lung

(2011) Melissa A. Kovach et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mast cell–associated alveolar inflammation in patients with atopic uncontrolled asthma

(2011) Cecilia K. Andersson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Asthma endotypes: A new approach to classification of disease entities within the asthma syndrome

(2011) Jan Lötvall et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Toll-like Receptor 7–triggered Immune Response in the Lung Mediates Acute and Long-Lasting Suppression of Experimental Asthma

(2010) Charoula Xirakia et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Infections and asthma: new insights into old ideas

(2010) C. M. Sevin et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Toll-like receptor 7 agonists are potent and rapid bronchodilators in guinea pigs

(2010) Elad H. Kaufman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The role of dendritic and epithelial cells as master regulators of allergic airway inflammation

(2010) Bart N Lambrecht et al.   LANCET

Toll-like receptors and innate immunity

(2009) Himanshu Kumar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Toll-like receptor 7 function is reduced in adolescents with asthma

(2009) M. Roponen et al.   EUROPEAN RESPIRATORY JOURNAL

Toll-like Receptors 3, 4, and 7 Are Expressed in the Enteric Nervous System and Dorsal Root Ganglia

(2009) Isabella Barajon et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Pseudomonas aeruginosa LPS or Flagellin Are Sufficient to Activate TLR-Dependent Signaling in Murine Alveolar Macrophages and Airway Epithelial Cells

(2009) Eloïse Raoust et al.   PLoS One

Novel site-specific mast cell subpopulations in the human lung

(2009) C K Andersson et al.   THORAX

IMIQUIMOD, A TOLL-LIKE RECEPTOR 7 LIGAND, INHIBITS AIRWAY REMODELLING IN A MURINE MODEL OF CHRONIC ASTHMA

(2008) Qiang Du et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Association analysis identifies TLR7 and TLR8 as novel risk genes in asthma and related disorders

(2008) S Moller-Larsen et al.   THORAX

Glial toll-like receptor signaling in central nervous system infection and autoimmunity

(2007) Pamela A. Carpentier et al.   BRAIN BEHAVIOR AND IMMUNITY