Mechanisms of tolerance induction in allergic disease: integrating current and emerging concepts

Sublingual Immunotherapy Affects Specific Antibody and TGF-β Serum Levels in Patients with Allergic Rhinitis

(2017) G. Ciprandi et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Epigenetic Regulation of Foxp3 Expression in Regulatory T Cells by DNA Methylation

(2014) G. Lal et al.   JOURNAL OF IMMUNOLOGY

Immunotherapy with oligomannose-coated liposomes ameliorates allergic symptoms in a murine food allergy model

(2012) Akiko Kawakita et al.   ALLERGY

Tolerogenic effects of interferon-gamma with induction of allergen-specific interleukin-10-producing regulatory B cell (Br1) changes in non-IgE-mediated food allergy

(2012) Joonyong Noh et al.   CELLULAR IMMUNOLOGY

Allergen-specific responses of CD19(+)CD5(+)Foxp3(+) regulatory B cells (Bregs) and CD4(+)Foxp3(+) regulatory T cell (Tregs) in immune tolerance of cow milk allergy of late eczematous reactions

(2012) Joonyong Noh et al.   CELLULAR IMMUNOLOGY

The induction of Treg cells by gut-indigenous Clostridium

(2012) Yuji Nagano et al.   CURRENT OPINION IN IMMUNOLOGY

Lung Natural Helper Cells Are a Critical Source of Th2 Cell-Type Cytokines in Protease Allergen-Induced Airway Inflammation

(2012) Timotheus Y.F. Halim et al.   IMMUNITY

Induction and suppression of allergic diarrhea and systemic anaphylaxis in a murine model of food allergy

(2012) Zeynep Yesim Kucuk et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A regulatory dendritic cell signature correlates with the clinical efficacy of allergen-specific sublingual immunotherapy

(2012) Aline Zimmer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Tolerance induction with T cell–dependent protein antigens induces regulatory sialylated IgGs

(2012) Carolin M. Oefner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Environmental biodiversity, human microbiota, and allergy are interrelated

(2012) I. Hanski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oral immunotherapy with immunodominant T-cell epitope peptides alleviates allergic reactions in a Balb/c mouse model of egg allergy

(2011) P. Rupa et al.   ALLERGY

The role of IgG antibodies in allergy and immunotherapy

(2011) R. Aalberse   ALLERGY

Functional rather than immunoreactive levels of IgG4 correlate closely with clinical response to grass pollen immunotherapy

(2011) M. H. Shamji et al.   ALLERGY

CD4+CD25+ T regulatory cells do not transfer oral tolerance to peanut allergens in a mouse model of peanut allergy

(2011) M. Marcondes Rezende et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Mechanisms of immunotherapy to aeroallergens

(2011) M. H. Shamji et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Mast Cell Interleukin-2 Production Contributes to Suppression of Chronic Allergic Dermatitis

(2011) Alon Y. Hershko et al.   IMMUNITY

A Requisite Role for Induced Regulatory T Cells in Tolerance Based on Expanding Antigen Receptor Diversity

(2011) Dipica Haribhai et al.   IMMUNITY

Development and preliminary clinical evaluation of a peptide immunotherapy vaccine for cat allergy

(2011) Margitta Worm et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Ingested allergens must be absorbed systemically to induce systemic anaphylaxis

(2011) Richard T. Strait et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Low diversity of the gut microbiota in infants with atopic eczema

(2011) Thomas R. Abrahamsson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Differentiation stage determines pathologic and protective allergen-specific CD4+ T-cell outcomes during specific immunotherapy

(2011) Erik Wambre et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Recognition of the Major Cat Allergen Fel d 1 through the Cysteine-rich Domain of the Mannose Receptor Determines Its Allergenicity

(2011) Mohamed Emara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sustained suppression by Foxp3+regulatory T cells is vital for infectious transplantation tolerance

(2011) Adrian R. Kendal et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dominant Th2 Differentiation of Human Regulatory T Cells upon Loss of FOXP3 Expression

(2011) L. Hansmann et al.   JOURNAL OF IMMUNOLOGY

Mucosal Allergic Sensitization to Cockroach Allergens Is Dependent on Proteinase Activity and Proteinase-Activated Receptor-2 Activation

(2011) N. G. Arizmendi et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells Enhance Mast Cell Production of IL-6 via Surface-Bound TGF- 

(2011) K. Ganeshan et al.   JOURNAL OF IMMUNOLOGY

Allergen-Specific Transforming Growth Factor-β-Producing CD19(+)CD5(+) Regulatory B-Cell (Br3) Responses in Human Late Eczematous Allergic Reactions to Cow's Milk

(2011) Jae Ho Lee et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Pulmonary CD103+ dendritic cells prime Th2 responses to inhaled allergens

(2011) H Nakano et al.   Mucosal Immunology

Intravenous gammaglobulin suppresses inflammation through a novel TH2 pathway

(2011) Robert M. Anthony et al.   NATURE

Functional Transforming Growth Factor-β Receptor Type II Expression by CD4+ T Cells in Peyer's Patches Is Essential for Oral Tolerance Induction

(2011) Rebekah S. Gilbert et al.   PLoS One

Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells

(2010) Y. Iwata et al.   BLOOD

Allergen-specific pattern recognition receptor pathways

(2010) Marsha Wills-Karp   CURRENT OPINION IN IMMUNOLOGY

Oral immunotherapy for food allergy

(2010) Brian P Vickery et al.   CURRENT OPINION IN PEDIATRICS

Phl p 5 resorption in human oral mucosa leads to dose-dependent and time-dependent allergen binding by oral mucosal Langerhans cells, attenuates their maturation, and enhances their migratory and TGF-β1 and IL-10–producing properties

(2010) Jean-Pierre Allam et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The Mannose Receptor Mediates the Uptake of Diverse Native Allergens by Dendritic Cells and Determines Allergen-Induced T Cell Polarization through Modulation of IDO Activity

(2010) P.-J. Royer et al.   JOURNAL OF IMMUNOLOGY

Protective and Pathogenic Roles for B Cells during Systemic Autoimmunity in NZB/W F1 Mice

(2010) K. M. Haas et al.   JOURNAL OF IMMUNOLOGY

Characterization of Protective Human CD4+CD25+ FOXP3+ Regulatory T Cells Generated with IL-2, TGF-β and Retinoic Acid

(2010) Ling Lu et al.   PLoS One

Systemically dispersed innate IL-13-expressing cells in type 2 immunity

(2010) A. E. Price et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conversion of Th2 memory cells into Foxp3+ regulatory T cells suppressing Th2-mediated allergic asthma

(2010) B.-S. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms Underlying Lineage Commitment and Plasticity of Helper CD4+ T Cells

(2010) J. J. O'Shea et al.   SCIENCE

Induction of Type 2 T Helper Cell Allergen Tolerance by IL-10–Differentiated Regulatory Dendritic Cells

(2009) Xiuling Li et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression

(2009) Ethan M. Shevach   IMMUNITY

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

CC16 Inhibits the Migration of Eosinophils Towards the Formyl Peptide fMLF but not Towards PGD2

(2009) Sofi Johansson et al.   INFLAMMATION

Adverse reactions during peanut oral immunotherapy home dosing

(2009) Pooja Varshney et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Food Allergy Herbal Formula-2 silences peanut-induced anaphylaxis for a prolonged posttreatment period via IFN-γ–producing CD8+ T cells

(2009) Kamal D. Srivastava et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Peptide immunotherapy in allergic asthma generates IL-10–dependent immunological tolerance associated with linked epitope suppression

(2009) John D. Campbell et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Development and Function of Regulatory B Cells Expressing IL-10 (B10 Cells) Requires Antigen Receptor Diversity and TLR Signals

(2009) K. Yanaba et al.   JOURNAL OF IMMUNOLOGY

Proteases Induce Production of Thymic Stromal Lymphopoietin by Airway Epithelial Cells through Protease-Activated Receptor-2

(2009) H. Kouzaki et al.   JOURNAL OF IMMUNOLOGY

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

(2009) Ye Zheng et al.   NATURE

Identification of IL-17-producing FOXP3+ regulatory T cells in humans

(2009) K. S. Voo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent Manner

(2009) A. Chaudhry et al.   SCIENCE

Tr1 and naturally occurring regulatory T cells induce IgG4 in B cells through GITR/GITR-L interaction, IL-10 and TGF-β

(2008) Judith S. Satoguina et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD4+CD25+ Regulatory T Cells Suppress Mast Cell Degranulation and Allergic Responses through OX40-OX40L Interaction

(2008) Giorgia Gri et al.   IMMUNITY

Adaptive Foxp3+ Regulatory T Cell-Dependent and -Independent Control of Allergic Inflammation

(2008) Maria A. Curotto de Lafaille et al.   IMMUNITY

A Regulatory B Cell Subset with a Unique CD1dhiCD5+ Phenotype Controls T Cell-Dependent Inflammatory Responses

(2008) Koichi Yanaba et al.   IMMUNITY

In vivo switch to IL-10–secreting T regulatory cells in high dose allergen exposure

(2008) Flurina Meiler et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors

(2008) Max Löhning et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein

(2008) Aurelien Trompette et al.   NATURE

Identification of a receptor required for the anti-inflammatory activity of IVIG

(2008) R. M. Anthony et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA