Review
Allergy
Padukudru Anand Mahesh, Mohammed Kaleem Ullah, Ashwaghosha Parthasarathi
Summary: Food allergy is a significant cause of morbidity and has a major impact on the quality of life of sufferers. However, most research on food allergy has been conducted in high-income countries. This study aims to summarize the existing literature on food allergy in India and other low-middle-income countries (LMIC). The findings reveal variations in food allergy prevalence and patterns among different LMICs, highlighting the need for international collaboration to assess the prevalence and burden of food allergy across representative samples from multiple LMICs.
CLINICAL AND EXPERIMENTAL ALLERGY
(2023)
Review
Allergy
Clara Westwell-Roper, Sharon To, Gordan Andjelic, Cynthia Lu, Boyee Lin, Lianne Soller, Edmond S. Chan, S. Evelyn Stewart
Summary: Parenting a child with food allergy can lead to impaired quality of life and family functioning, with anxiety being a critical component of distress. Existing measures for general anxiety symptoms and FA-specific parental factors fail to adequately capture dimensions of FA-specific anxiety, suggesting the need for further improvement in assessment and monitoring of FAA.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2022)
Article
Allergy
Sloan A. Lewis, Aaron Sutherland, Ferran Soldevila, Luise Westernberg, Minori Aoki, April Frazier, Synaida Maiche, Mich Erlewyn-Lajeunesse, Hasan Arshad, Stephanie Leonard, Susan Laubach, Jennifer A. Dantzer, Robert A. Wood, Alessandro Sette, Gregory Seumois, Pandurangan Vijayanand, Bjoern Peters
Summary: This study examines the differences in allergen-specific T cells in cow milk allergic patients, aiming to identify potential diagnostic markers. The findings reveal significant changes in the transcriptional program and clonality of CM antigen-specific T cells in patients with cow milk allergy compared to those without. The increase in a specific type of T cells, FOXP3+ cells, is suggested as a potential diagnostic marker. Additionally, there is an observed increase in TH2 cells and markers associated with allergic diseases in cow milk allergic patients. These findings have implications for monitoring disease progression and the effectiveness of immunotherapy.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2023)
Review
Medicine, General & Internal
Jooyoung Cheon, Chung Min Cho, Hyo Jin Kim, Dong Hee Kim
Summary: This systematic review investigated the effects of education programs for parents and children with food allergies on their quality of life. The results showed a lack of educational interventions for this group, with only a few studies demonstrating significant improvements in quality of life through education. Therefore, there is a need to actively develop and apply educational interventions.
Article
Allergy
Dah-Tay Jang, Maria Perez Sabido, Elisa Buendia, Laura Ibanez, Maria Nieto, Ester Bartoll, Blanca Selva, Sonia Uixera, Antonio Nieto, Angel Mazon
Summary: This study aimed to validate a Spanish translation of the Food Allergy Independent Measure (FAIM) and the EuroPrevall Food Allergy Quality of Life Questionnaire-Child Form (FAQLQ-CF) for children aged 8-12 years. The results showed acceptable internal consistency, good construct validity, and discriminant capacity for both questionnaires.
ALLERGOLOGIA ET IMMUNOPATHOLOGIA
(2022)
Article
Pediatrics
Waheeda Samady, Christopher Warren, Lucy A. A. Bilaver, Justin Zaslavsky, Jialing Jiang, Ruchi Gupta
Summary: This study aimed to explore US caregivers' awareness, beliefs, practices, and outcomes around peanut introduction. The survey revealed disparities and shortcomings in the practice of peanut introduction, despite some caregivers being aware of the peanut allergy prevention guidelines. Therefore, future efforts should focus on increasing guideline adherence, providing support for medical providers, and educating about the true incidence of reactions.
Article
Allergy
Jennifer A. Hoang, Alper Celik, Christian Lupinek, Rudolf Valenta, Lucy Duan, Ruixue Dai, May G. Brydges, Aimee Dubeau, Claire Lepine, Samantha Wong, Mara Alexanian-Farr, Ahuva Magder, Padmaja Subbarao, Julia E. M. Upton, Klara Schmidthaler, Zsolt Szepfalusi, Arun Ramani, Thomas Eiwegger
Summary: This study aimed to create models for statistical integration of allergen-specific IgE to peanut/tree nut allergens from three IgE test platforms. Results demonstrated the ability to model allergen-specific relationships with acceptable measures of fit for peanut and tree nut sIgE testing, providing options for data aggregation in future meta-analyses.
Article
Nutrition & Dietetics
Fumiko Okazaki, Hiroyuki Wakiguchi, Yuno Korenaga, Kazumasa Takahashi, Hiroki Yasudo, Ken Fukuda, Mototsugu Shimokawa, Shunji Hasegawa
Summary: Little is known about the clinical features of food protein-induced enterocolitis syndrome (FPIES) in patients with Down syndrome (DS). This study found that FPIES in DS patients is associated with greater severity and earlier onset of symptoms. Cow's milk formula and wheat were the main causative foods. The surgical history of colostomy and postoperative nutrition may contribute to the onset of FPIES. Therefore, the use of amino acid-based formula should be considered for DS children undergoing gastrointestinal surgeries, and FPIES should be considered when acute gastrointestinal disease is suspected in DS children.
Article
Allergy
Naomi Sugunasingha, Fergal W. Jones, George du Toit, Christina J. Jones
Summary: This study aimed to improve the quality of life for parents of children with food allergies through an online self-help website. The results indicate that the website was not suitable for the general population, but it may be effective for parents with depression symptoms. The study identified intolerance of uncertainty and self-efficacy as potential targets for intervention.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2022)
Article
Nursing
Hwayoung Kwen, Pok-Ja Oh
Summary: This study aimed to develop a mobile web-based educational program for parents of school-aged children with food allergies and evaluate its effectiveness. The results showed that the program significantly improved parents' knowledge, self-efficacy, and practice behavior in food allergy and anaphylaxis management.
ASIAN NURSING RESEARCH
(2022)
Article
Allergy
Josefin Ullberg, Mareike Fech-Bormann, Ulrika L. Fagerberg
Summary: In this study of 113 Swedish children, cow's milk, fish, and oat were the most common trigger foods for FPIES. Most patients reacted to a single food, and IgE sensitization was rare.
Review
Nutrition & Dietetics
Alexandru Cosmin Pantazi, Cristina Maria Mihai, Adriana Luminita Balasa, Tatiana Chisnoiu, Ancuta Lupu, Corina Elena Frecus, Larisia Mihai, Adina Ungureanu, Mustafa Ali Kassim Kassim, Antonio Andrusca, Maria Nicolae, Viviana Cuzic, Vasile Valeriu Lupu, Simona Claudia Cambrea
Summary: The intestinal microbiota is a diverse and complex microecosystem that stabilizes by the age of three and plays a crucial role in human health, particularly in early childhood. Dysbiosis has been linked to the development of allergic diseases, such as atopic dermatitis, asthma, and food allergies. Next-generation sequencing methods have improved our understanding of the relationship between dysbiosis and allergic diseases. This review paper aims to synthesize the current knowledge on the development of the intestinal microbiota, its long-term impact on health, and the connection between dysbiosis and allergic diseases, as well as interventions for prevention and treatment.
Review
Allergy
Veronika Hoefer, Matteo Martini, Sabine Doelle-Bierke, Margitta Worm, Maria Beatrice Bilo
Summary: The impact on health-related quality of life (HRQL) is crucial for patients with allergies and anaphylaxis. This narrative review focuses on HRQL in allergic patients with food and venom allergies, which are the most common triggers for severe and life-threatening reactions. The review highlights the availability of standardized assessment tools for measuring HRQL in these patients and the various factors that can influence HRQL, including sociodemographic data and external factors. The review also emphasizes the importance of considering lifestyle factors and measuring individual changes in HRQL during specific immunotherapy.
CLINICAL AND EXPERIMENTAL ALLERGY
(2023)
Article
Allergy
Nannan Jiang, Wei Xu, Li Xiang
Summary: This study identified infants as a high-risk group for anaphylaxis in Chinese children, with food being the main culprit, particularly cow's milk and egg. Different age groups presented with varying clinical symptoms, with hives and vomiting being more common in infants.
WORLD ALLERGY ORGANIZATION JOURNAL
(2021)
Review
Nutrition & Dietetics
Carlo Caffarelli, Arianna Giannetti, Arianna Rossi, Giampaolo Ricci
Summary: Eggs are essential in the human diet, but they are also the most common food allergen. This paper highlights the importance of eggs in a child's diet and analyzes the risk factors for developing egg allergies. It also discusses interventions to reduce the occurrence of food allergies and provides a synthesis of the research study based on the latest guidelines and position papers.
