Article
Computer Science, Interdisciplinary Applications
Joachim Ee En Ong, Shi Lei Teng, Duncan Angus McGrouther, Hwa Liang Leo, Yoke Rung Wong
Summary: Understanding the interaction between synovial fluid pressure and ligament stresses is important for improving wrist treatment. This study found that the influence of synovial fluid pressure on the ligament can be negligible, suggesting that fluid-structure interactions can be foregone in wrist joint simulations. Future research can explore other structures that may contribute to ligament stresses.
COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING
(2023)
Article
Medicine, General & Internal
David Keohane, David Morrissey
Summary: This paper presents a novel surgical technique for posterior sternoclavicular dislocations, which involves relocating the joint and securing it with nylon suture tape. All patients showed significant improvement in functional outcomes post-operatively, with no reported intra-operative or post-operative complications. The technique described in this paper appears to be safer than existing methods and maintains good functional results.
IRISH JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Moon-Chang Choi, Jiwon Jo, Myeongjin Lee, Jonggwan Park, Yoonkyung Park
Summary: The study found that the antimicrobial peptide Cramp induces chondrocyte catabolism via the NF-kappa B signaling pathway, accelerating the progression of OA and leading to cartilage degeneration.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Polymer Science
Marina Koland, Anoop Narayanan Vadakkepushpakath, Anish John, Arunraj Tharamelveliyil Rajendran, Indu Raghunath
Summary: Intra-articular application of thermosensitive gels can prolong drug retention and relieve inflammation in joint diseases. Thermosensitive hydrogels, especially those using temperature-sensitive block copolymers or poloxamers, have been extensively studied and preferred due to their controlled gelation properties and ease of drug loading. However, challenges such as low response time, fragility, and biocompatibility need to be addressed. The stability and biodegradability of implant hydrogels play a crucial role in controlling the drug release rate and treatment efficacy.
Article
Orthopedics
Yang Xu, Xing-chen Li, Chang-jun Guo, Xiang-yang Xu
Summary: The study showed that intra-articular opening osteotomy combined with lateral ligament reconstruction is an effective method to treat Takakura 3B ankle arthritis with medial distal tibial platform erosion.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2021)
Review
Orthopedics
Matthew T. Provencher, David L. Bernholt, Liam A. Peebles, Peter J. Millett
Summary: Chronic instability of the sternoclavicular joint can be treated with surgical options, especially for individuals with higher activity levels. Posterior instability has a poorer prognosis and poses a risk to mediastinal structures, thus requiring surgical intervention.
JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS
(2022)
Article
Orthopedics
Jiajun Qin, Qiang Fu, Qing Zhou, Helin Wu, Xiaosong Zhi, Feng Xu, Xianhua Cai, Shijun Wei
Summary: The fully intra-articular lasso-loop stitch technique for arthroscopic ATFL repair using the Arthro-Pierce instrument was found to be reliable and safe, with no nerve injuries encountered. Patients showed significant improvements in joint function and pain scores.
FOOT & ANKLE INTERNATIONAL
(2022)
Article
Orthopedics
Ahmed Mabrouk, Jae-Sung An, Loddo Glauco, Christophe Jacque, Kristian Kley, Akash Sharma, Matthieu Ollivier
Summary: This study aims to investigate the correlation between the joint line convergence angle (JLCA) and the progression of osteoarthritis (OA) in patients with unicompartmental varus knee OA. The results showed that an increase in JLCA is closely associated with OA progression.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2023)
Review
Medicine, General & Internal
Maciej Checinski, Kamila Checinska, Natalia Turosz, Anita Brzozowska, Dariusz Chlubek, Maciej Sikora
Summary: This mapping review aims to discuss the current research directions on intracavitary temporomandibular joints (TMJs) injections for patients with temporomandibular joint disorders (TMDs). A total of 152 qualified reports were identified from 2712 records, and the results showed that viscosupplementation with hyaluronic acid (HA) was the best-documented injectable administered into TMJ cavities, but there is a growing trend in the use of centrifuged blood preparations for injections.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Orthopedics
Jae H. Lee, Keewon Kim, Sun G. Chung
Summary: The study found that knees with osteoarthritis exhibited differences in mechanical properties compared to other clinical parameters, showing increased intra-articular pressure and synovial stiffness. The synovium of knees with osteoarthritis stretched earlier, and intra-articular pressure characteristics could be used for clinical evaluation of the synovium.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2022)
Article
Pharmacology & Pharmacy
Jin Qiu, Bingqiang Hua, Xiaoping Ye, Xianwen Liu
Summary: Kartogenin (KGN) is a small-molecule compound that promotes chondrogenic differentiation of mesenchymal stem cells and alleviates knee joint osteoarthritis. Its effect on temporomandibular joint osteoarthritis (TMJOA) remains unclear.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Multidisciplinary Sciences
Elin Sward, Maria Wilcke
Summary: This study retrospectively analyzed the effect of intra-articular PRP injection on patients with painful osteoarthritis in the thumb basal joint or STT joint. The results showed that PRP injections had no effect on pain, functional evaluation, grip strength, or key pinch. Further placebo-controlled studies are needed to investigate the efficacy of PRP in osteoarthritis of the thumb basal joint and STT joint.
Article
Medicine, General & Internal
Kate M. Parker, Jeremy S. Somerson, Winston J. Warme
Summary: SCJ injuries, though rare, can cause significant pain and disability. Conservative management can improve symptoms in most cases, but surgical intervention may be necessary for patients with persistent symptoms. Various surgical stabilization techniques are documented, but the lack of cases has hindered the development of a gold standard.
Review
Orthopedics
D. Wang, X-Q Chai, S-S Hu, F. Pan
Summary: Osteoarthritis, as the most common form of joint disease, is a major cause of chronic pain. Recent studies have found that the accumulation of synovial macrophages is associated with pain sensitization in osteoarthritis. However, targeting these macrophages for treatment is challenging due to their complexity and plasticity. Advanced technologies have provided insights into the molecular mechanisms of different subsets of synovial macrophages in osteoarthritis development.
OSTEOARTHRITIS AND CARTILAGE
(2022)
Article
Orthopedics
Hugo C. Rodriguez, Kevin L. Mekkawy, Adam Watkins, Martin W. Roche, W. Vincent Burke, Raul G. Gosthe
Summary: This study aimed to investigate the risk of prosthetic joint infection (PJI) after intra-articular corticosteroid injection (IACI) in patients who underwent unicompartmental knee arthroplasty (UKA). The results showed that the incidence of PJI was higher in patients who received IACI compared to the control group. Surgeons should take this increased risk into consideration when deciding whether to perform injections in UKA.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Orthopedics
Michiel Van Parys, Osama Alkiar, Nerissa Naidoo, Alexander Van Tongel, Lieven De Wilde
Summary: This study evaluated and compared the coracoacromial complex in pathologic shoulders (glenohumeral osteoarthritis [GHOA] and cuff tear arthropathy [CTA]) and nonpathologic shoulders. The results showed significant differences in acromial overhang, acromion-glenoid angle, and acromial height among the different shoulder groups.In conclusion, the acromial part of the complex was turned more posteriorly in both pathologic groups, and the coracoacromial complex was more cranial to the glenoid center in the GHOA group.
JOURNAL OF SHOULDER AND ELBOW SURGERY
(2021)
Article
Orthopedics
Lotte Verstuyft, Laurence Vergison, Alexander Van Tongel, Lieven De Wilde
Summary: This study indicates that in patients with uncontained glenoid bone defects undergoing revision to an RTSA, the use of the CPPSP technique can achieve similar clinical outcomes compared to using bone grafts. While the CPPSP technique results in a significant increase in strength, it may lead to different complications that need to be carefully considered.
JOURNAL OF SHOULDER AND ELBOW SURGERY
(2021)
Article
Materials Science, Biomaterials
Monica Thukkaram, Mykhailo Vaidulych, Ondrej Kylian, Petra Rigole, Sheida Aliakbarshirazi, Mahtab Asadian, Anton Nikiforov, Hynek Biederman, Tom Coenye, Gijs Du Laing, Rino Morent, Alexander Van Tongel, Lieven De Wilde, Kim Verbeken, Nathalie De Geyter
Summary: Titanium based implants are often associated with infection, making it crucial to find effective strategies to prevent infections. This study investigated nanocomposite coatings with copper nanoparticles deposited on titanium discs for antibacterial activity and biocompatibility. Coatings with higher numbers of copper nanoparticles showed excellent antibacterial activity without harming osteoblast cells, indicating a promising solution for preventing infections in implant surgery.
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Caroline Muylaert, Cedric Boulet, Nico Buls, Scott Wuertzer, Nicole Pouliart, Freddy Machiels, Michel De Maeseneer
Summary: This study aimed to investigate if shoulder immobilization could prevent contrast leakage after arthrography. The results showed that strict immobilization of the shoulder cannot avoid leakage and negatively affects image quality and interpretation.
CANADIAN ASSOCIATION OF RADIOLOGISTS JOURNAL-JOURNAL DE L ASSOCIATION CANADIENNE DES RADIOLOGISTES
(2022)
Article
Orthopedics
Ian Peeters, Nele Pien, Arn Mignon, Lana Van Damme, Peter Dubruel, Sandra Van Vlierberghe, Diego Mantovani, Valerie Vermeulen, David Creytens, Alexander Van Tongel, Stijn Schauvliege, Katleen Hermans, Lieven De Wilde, Ann Martens
Summary: A reinforced tubular, medicated electrospun construct was developed for deep flexor tendon repair, showing similar strength and anti-inflammatory and anti-adhesion effects as a modified Kessler suture. Different surgical techniques demonstrated varied adhesion patterns postoperatively, but all showed good to excellent repair outcomes histologically, suggesting successful combination of mechanical and biological repair strategies for flexor tendon repair.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2022)
Review
Engineering, Biomedical
Anne Karelse, Alexander Van Tongel, Taco Gosens, Sara De Boey, Lieven F. De Wilde, Nicole Pouliart
Summary: National shoulder arthroplasty registries lack common datasets and internationally agreed parameters, which hinders pooling and comparison of data for evidence-based decision-making. Parameters relevant to outcome and failure of shoulder prostheses are often not included in current registries, highlighting the need for adjustments to be made.
EXPERT REVIEW OF MEDICAL DEVICES
(2021)
Article
Orthopedics
Ian Peeters, Thomas Braeckevelt, Tanneke Palmans, Lieven De Wilde, Alexander Van Tongel
Summary: This study demonstrates kinematic differences between AC, CC, or combined ligament reconstruction strategies. Each technique can partially restore different elements of joint kinematics, but none completely restore the shoulder girdle to its preinjured state.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2022)
Article
Orthopedics
Ian Peeters, Valerie Vermeulen, Alexander Van Tongel, Ann Martens, Lieven De Wilde
Summary: This ex vivo study demonstrates that the use of a tubular braided construct for repair allows for immediate rehabilitation and improves range of motion after flexor tendon repair. The tubular braided construct withstands higher loads in both static and cyclic tests compared to the control group, providing greater strength.
JOURNAL OF HAND SURGERY-AMERICAN VOLUME
(2023)
Letter
Orthopedics
Alexander Van Tongel
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2022)
Article
Rehabilitation
E. A. H. D. Duijn, S. van Roy, Y. H. J. M. Karel, S. Provyn, N. Pouliart
Summary: This study demonstrates a strong level of agreement and reliability among a limited group of physical therapists, a radiologist, and an orthopedic surgeon in detecting rotator cuff pathology and involvement of the rotator cable through the use of musculoskeletal ultrasound on fresh frozen cadaver shoulders.
MUSCULOSKELETAL SCIENCE AND PRACTICE
(2022)
Article
Anatomy & Morphology
Valerie Vermeulen, Elaine Kozma, Arne Delsupehe, Pieter Cornillie, Emmelie Stock, Alexander Van Tongel, Lieven De Wilde, Evie E. Vereecke
Summary: In this study, the three-dimensional morphology of the scapula in humans and great apes was quantified and compared using an image-based methodology originally developed for orthopaedic practice. The results showed significant differences in scapular morphology between humans and great apes, with chimpanzees showing a morphology more similar to humans. These differences may be related to differences in mobility and loading regime of the shoulder.
JOURNAL OF ANATOMY
(2023)
Review
Engineering, Biomedical
Olivier Verstraete, Alexander Van Tongel, Lieven De Wilde, Ian Peeters
Summary: This systematic review evaluated the biomechanical role of acromioclavicular capsule/ligament reconstruction techniques after an acromioclavicular joint injury. The results showed that reconstruction of the acromioclavicular capsule/ligaments can increase anteroposterior and rotational stability of the shoulder joint, but an optimal reconstruction technique that mimics the native joint is not yet available.
CLINICAL BIOMECHANICS
(2023)
Article
Orthopedics
Jan Herregodts, Stijn Herregodts, Eva De Vries, Lieven De Wilde, Alexander Van Tongel
Summary: This study used 3-dimensional computed tomography (CT) reconstructions of the elbow joint of healthy volunteers to determine the demographic variability of the ulna and the relationship between two angles in the frontal plane. The study found a wide range of valgus angulation of the proximal ulnar canal, and the available elbow implant designs do not cover the variability in the population.
JOURNAL OF SHOULDER AND ELBOW SURGERY
(2023)
Article
Orthopedics
Philip Tack, Sofie Vanhaverbeke, Lieven De Wilde, Alexander Van Tongel
Summary: This research confirms that hyaluronic acid injections can be used for non-operative treatment of degenerative rotator cuff tears in older people, improving pain and shoulder function. Most patients do not require additional treatment and surgical intervention is rare.
ACTA ORTHOPAEDICA BELGICA
(2022)
Article
Orthopedics
Silvio Lampaert, Jan Herregodts, Lieven De Wilde, Alexander Van Tongel
Summary: This study evaluated the location of radial head fracture fragments and the influence of Mason type on the size of the fracture fragment. The results showed that the fracture fragments were mainly located in the anteromedial quadrant and that the average fracture fragment size was significantly larger in Mason type II compared to type I fractures.
ACTA ORTHOPAEDICA BELGICA
(2022)