Tumor cell-derived Timp-1 is necessary for maintaining metastasis-promoting Met-signaling via inhibition of Adam-10

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity

(2010) Keith Brew et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Matrix Metalloproteinase-9 Functions as a Tumor Suppressor in Colitis-Associated Cancer

(2010) P. Garg et al.   CANCER RESEARCH

Tissue inhibitor of metalloproteinases-1-induced scattered liver metastasis is mediated by hypoxia-inducible factor-1α

(2010) Florian Schelter et al.   CLINICAL & EXPERIMENTAL METASTASIS

Identification of a Survival-independent Metastasis-enhancing Role of Hypoxia-inducible Factor-1α with a Hypoxia-tolerant Tumor Cell Line

(2010) Florian Schelter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Disintegrin and Metalloproteinase-10 (ADAM-10) Mediates DN30 Antibody-induced Shedding of the Met Surface Receptor

(2010) Florian Schelter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MET signalling: principles and functions in development, organ regeneration and cancer

(2010) Livio Trusolino et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Avoiding spam in the proteolytic internet: Future strategies for anti-metastatic MMP inhibition

(2009) Achim Krüger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ectodomain shedding of E-cadherin and c-Met is induced by Helicobacter pylori infection

(2009) Wiebke Schirrmeister et al.   EXPERIMENTAL CELL RESEARCH

Tissue inhibitor of metalloproteinases-1-induced scattered liver metastasis is mediated by host-derived urokinase-type plasminogen activator

(2009) Florian Schrötzlmair et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Low expression of tissue inhibitor of metalloproteinases-1 (TIMP-1) in glioblastoma predicts longer patient survival

(2009) Charlotte Aaberg-Jessen et al.   JOURNAL OF NEURO-ONCOLOGY

High levels of serum TIMP-1 correlate with advanced disease and predict for poor survival in patients with multiple myeloma treated with novel agents

(2009) Evangelos Terpos et al.   LEUKEMIA RESEARCH

mRNA expression of matrix metalloproteinases (MMPs) 2 and 9 and tissue inhibitor of matrix metalloproteinases (TIMPs) 1 and 2 in childhood acute lymphoblastic leukemia: Potential role of TIMP1 as an adverse prognostic factor

(2009) Carlos Alberto Scrideli et al.   LEUKEMIA RESEARCH

Down-Regulation of the Met Receptor Tyrosine Kinase by Presenilin-dependent Regulated Intramembrane Proteolysis

(2009) Bénédicte Foveau et al.   MOLECULAR BIOLOGY OF THE CELL

Functional genetic mouse models: promising tools for investigation of the proteolytic internet

(2008) Achim Krüger   BIOLOGICAL CHEMISTRY

Matrix Metalloproteinase-8 Functions as a Metastasis Suppressor through Modulation of Tumor Cell Adhesion and Invasion

(2008) A. Gutierrez-Fernandez et al.   CANCER RESEARCH

ADAM10 as a Target for Anti-Cancer Therapy

(2008) Marcia Moss et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Distinct Functionality of Tumor Cell-Derived Gelatinases during Formation of Liver Metastases

(2008) M. Gerg et al.   MOLECULAR CANCER RESEARCH

Drug development of MET inhibitors: targeting oncogene addiction and expedience

(2008) Paolo M. Comoglio et al.   NATURE REVIEWS DRUG DISCOVERY