HEB in the Spotlight: Transcriptional Regulation of T-Cell Specification, Commitment, and Developmental Plasticity

Transcriptional priming of intrathymic precursors for dendritic cell development

(2011) A. J. Moore et al.   DEVELOPMENT

The earliest intrathymic precursors of CD8α+ thymic dendritic cells correspond to myeloid-type double-negative 1c cells

(2011) Hervé Luche et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

T Cell Lineage Commitment: Identity and Renunciation

(2011) E. V. Rothenberg   JOURNAL OF IMMUNOLOGY

A critical role for TCF-1 in T-lineage specification and differentiation

(2011) Brittany Nicole Weber et al.   NATURE

Notch3 Is Dispensable for Thymocyte β-Selection and Notch1-Induced T Cell Leukemogenesis

(2011) Sara Suliman et al.   PLoS One

Functions of Notch Signaling in the Immune System: Consensus and Controversies

(2010) Julie S. Yuan et al.   Annual Review of Immunology

Identification of an NK/T cell-restricted progenitor in adult bone marrow contributing to bone marrow- and thymic-dependent NK cells

(2010) H. Nozad Charoudeh et al.   BLOOD

Developmental progression of fetal HEB−/− precursors to the pre-T-cell stage is restored by HEBAlt

(2010) Marsela Braunstein et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Fate Mapping Reveals Separate Origins of T Cells and Myeloid Lineages in the Thymus

(2010) Susan M. Schlenner et al.   IMMUNITY

Critical roles of Bcl11b in T-cell development and maintenance of T-cell identity

(2010) Pentao Liu et al.   IMMUNOLOGICAL REVIEWS

From the cradle to the grave: activities of GATA-3 throughout T-cell development and differentiation

(2010) Tomonori Hosoya et al.   IMMUNOLOGICAL REVIEWS

HEBAlt enhances the T-cell potential of fetal myeloid-biased precursors

(2010) Marsela Braunstein et al.   INTERNATIONAL IMMUNOLOGY

Context-Dependent Regulation of Hematopoietic Lineage Choice by HEBAlt

(2010) D. Wang et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Thymic NK Cells Develop Independently from T Cell Precursors

(2010) V. S. G. Ribeiro et al.   JOURNAL OF IMMUNOLOGY

Fine-Scale Staging of T Cell Lineage Commitment in Adult Mouse Thymus

(2010) M. A. Yui et al.   JOURNAL OF IMMUNOLOGY

HEB-Deficient T-Cell Precursors Lose T-Cell Potential and Adopt an Alternative Pathway of Differentiation

(2010) M. Braunstein et al.   MOLECULAR AND CELLULAR BIOLOGY

An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells

(2010) Louise M D'Cruz et al.   NATURE IMMUNOLOGY

Reprogramming of T Cells to Natural Killer-Like Cells upon Bcl11b Deletion

(2010) P. Li et al.   SCIENCE

An Early T Cell Lineage Commitment Checkpoint Dependent on the Transcription Factor Bcl11b

(2010) L. Li et al.   SCIENCE

GATA-3 is required for early T lineage progenitor development

(2009) Tomonori Hosoya et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transcription Factor E2-2 Is an Essential and Specific Regulator of Plasmacytoid Dendritic Cell Development

(2008) Babacar Cisse et al.   CELL

Transcription factor expression dynamics of early T-lymphocyte specification and commitment

(2008) Elizabeth-Sharon David-Fung et al.   DEVELOPMENTAL BIOLOGY

E-box protein E2-2 is a crucial regulator of plasmacytoid DC development

(2008) Eiji Esashi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

E2A Proteins Promote Development of Lymphoid-Primed Multipotent Progenitors

(2008) Sheila Dias et al.   IMMUNITY

Delta-like 4 is indispensable in thymic environment specific for T cell development

(2008) Katsuto Hozumi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment

(2008) Ute Koch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A role for E2-2 at the DN3 stage of early thymopoiesis

(2008) Ingela Wikström et al.   MOLECULAR IMMUNOLOGY

The earliest thymic progenitors for T cells possess myeloid lineage potential

(2008) J. Jeremiah Bell et al.   NATURE

Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4+ T cells

(2008) Lie Wang et al.   NATURE IMMUNOLOGY

B-cell receptor activation inhibits AID expression through calmodulin inhibition of E-proteins

(2008) J. Hauser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of lymphocyte progenitor survival by the proapoptotic activities of Bim and Bid

(2008) M. Mandal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA