Article
Biochemistry & Molecular Biology
Shufei Zeng, Chang Chu, Cornelia Doebis, Volker von Baehr, Berthold Hocher
Summary: There is a strong positive linear correlation between free 25(OH)D (f25(OH)D) and total 25(OH)D, making them useful for assessing vitamin D levels. The recommended threshold level for f25(OH)D is 8.499 pg/mL, corresponding to a target concentration of at least 30 ng/mL for t25(OH)D. The upper limit for vitamin D is still unclear, with most experts favoring a upper limit of 100 ng/mL for t25(OH)D.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2021)
Article
Nutrition & Dietetics
Guowei Li, Likang Li, Jonathan D. Adachi, Ruoting Wang, Zebing Ye, Xintong Liu, Lehana Thabane, Gregory Y. H. Lip
Summary: This study found a quasi J-shaped relationship between serum circulating 25-hydroxyvitamin D (25(OH)D) level and risk of recurrent stroke in patients with a stroke history. The lowest risk of recurrent stroke was observed at a 25(OH)D level of approximately 60 nmol/L, which was associated with a 48% reduction in risk compared to a level of 10 nmol/L.
Article
Nutrition & Dietetics
RuTong Wang, Weijing Wang, Ping Hu, Ronghui Zhang, Xue Dong, Dongfeng Zhang
Summary: This study aimed to evaluate the association between dietary vitamin D intake and serum vitamin D concentrations with cognitive performance in older Americans. The results showed a positive association between dietary vitamin D intake, serum total 25-hydroxyvitamin D, and cognitive performance, with no significant gender differences in the associations. Further research is needed to clarify the effects of dietary vitamin D intake and specific serum D concentrations on cognitive performance.
Review
Biochemistry & Molecular Biology
Nataliia Karpova, Olga Dmitrenko, Ekaterina Arshinova, Malik Nurbekov
Summary: 25-hydroxyvitamin D (25(OH)D) is essential during pregnancy and deficiency can increase the risk of preeclampsia. Current research on the effects of 25(OH)D deficiency and supplementation on pregnancy outcomes shows contradictory results.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Nutrition & Dietetics
Benjamin Levy, Karen M. O'Callaghan, Huma Qamar, Abdullah Al Mahmud, Alison D. Gernand, M. Munirul Islam, Daniel E. Roth
Summary: Variability in maternal and infant 25(OH)D levels following vitamin D supplementation is largely determined by supplemental vitamin D intake and initial 25(OH)D levels. Other characteristics contribute minimally to the variance. Maternal delivery 25(OH)D and prenatal vitamin D intake are the major determinants of neonatal 25(OH)D levels. The variance in later infancy 25(OH)D can only be partly explained by various biological, sociodemographic, and laboratory-related characteristics.
JOURNAL OF NUTRITION
(2021)
Article
Agriculture, Dairy & Animal Science
Miranda C. M. Dosi, Chris M. Riggs, Jessica May, Adele Lee, Eugenio Cillan-Garcia, Joe Pagan, Bruce C. McGorum
Summary: Hong Kong racehorses have low serum vitamin D-2 and total vitamin D concentrations and rely on D-3 supplementation to maintain adequate vitamin D status.
Article
Nutrition & Dietetics
Aislinn F. McCourt, Steven L. Mulrooney, Graham J. O'Neill, E. Dolores O'Riordan, Aifric M. O'Sullivan
Summary: Food fortification of vitamin D improves intake but is not mandatory in many countries. Combining vitamin D with different dietary lipids can affect absorption. This randomized trial investigated the effect of the lipid composition of a vitamin D-fortified dairy drink on 25-hydroxyvitamin D concentrations. The results showed that for individuals classified as vitamin D-insufficient, all forms of vitamin D supplementation increased concentrations significantly. However, for vitamin D-sufficient participants, only the coconut oil dairy drink and supplement had significant increases. There was no effect on metabolic health biomarkers.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Oncology
Sha Sha, Li-Ju Chen, Hermann Brenner, Ben Schoettker
Summary: The associations of serum 25(OH)D levels and vitamin D supplementation with total and site-specific cancer mortality were investigated. Vitamin D deficiency and insufficiency were found to be associated with increased mortality from multiple common cancers.
EUROPEAN JOURNAL OF CANCER
(2023)
Article
Medical Laboratory Technology
Francesco Vierucci, Lara Fusani, Alessandro Saba, Tania Minucciani, Maria Paola Belluomini, Raffaele Domenici, Gian Luca Bracco, Angelina Vaccaro, Giovanni Federico
Summary: This study assessed the relationship between assumed risk factors for maternal vitamin D deficiency and levels of cord blood 25(OH)D-3 and C-3-epimer. The results showed that vitamin D deficiency was common in newborns, especially those born to mothers who did not receive vitamin D supplementation and had poor sun exposure.
CLINICA CHIMICA ACTA
(2022)
Article
Nutrition & Dietetics
Sonja Soininen, Aino-Maija Eloranta, Ursula Schwab, Timo A. Lakka
Summary: The purpose of this study was to investigate the intake and sources of vitamin D, as well as the determinants of serum 25-hydroxyvitamin D (S-25(OH)D) in Finnish adolescents. The results showed that most adolescents had vitamin D intake at the recommended level, although a quarter did not meet the recommended intake and almost a third had low levels of S-25(OH)D. The main determinants of S-25(OH)D were vitamin D intake from supplements, consumption of milk products, consumption of meat products, travels to sunny countries, and average daylight time.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Review
Nutrition & Dietetics
Mohammed M. Hassanein, Hasniza Zaman Huri, Kauser Baig, Abduelmula R. Abduelkarem
Summary: Hormonal fluctuations, excessive clothing covering, sunscreen use, changes in body fat composition, a vitamin D-deficient diet, and a sedentary lifestyle can all predispose postmenopausal women to vitamin D deficiency. An effective supplementation plan requires a thorough understanding of underlying factors to achieve the desired therapeutic concentrations. This study conducted a systematic review to identify predictors that affect vitamin D status in postmenopausal women.
Article
Nutrition & Dietetics
Naoko Tsugawa, Mayu Nishino, Akiko Kuwabara, Honami Ogasawara, Maya Kamao, Shunjiro Kobayashi, Junichi Yamamura, Satoshi Higurashi
Summary: The study found that the low vitamin D status in recent lactating mothers may have decreased the concentrations of vitamin D and 25OHD in breast milk, compared to the 1980s. This has important implications for improving the vitamin D status of lactating mothers and infants.
Review
Nutrition & Dietetics
Manuel Rupprecht, Stefan Wagenpfeil, Jakob Schoepe, Reinhold Vieth, Thomas Vogt, Joerg Reichrath
Summary: A meta-analysis was conducted to investigate the impact of oral vitamin D supplementation on serum 25-hydroxyvitamin D levels in healthy adults in Europe. The findings suggest that vitamin D supplementation can significantly increase serum 25(OH)D levels, with the effect influenced by dosage and baseline serum levels.
Article
Nutrition & Dietetics
Zhenyu Zhong, Guannan Su, Liping Du, Qingyun Zhou, Fuzhen Li, Wei Chi, Shengyun Liu, Meifen Zhang, Xianbo Zuo, Peizeng Yang
Summary: This study using Mendelian randomization found that genetically increased serum 25-hydroxyvitamin D levels were associated with a higher risk of Behcet's disease, with data from Chinese and Turkish cohorts supporting this conclusion. The contribution to Behcet's disease risk may increase with higher levels of vitamin D.
CLINICAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Shuangshuang Ma, Wanjun Yin, Peng Wang, Haixia Wang, Lei Zhang, Ruixue Tao, Honglin Hu, Xiaomin Jiang, Ying Zhang, Fangbiao Tao, Peng Zhu
Summary: This study aimed to assess the effect of vitamin D supplementation during pregnancy on glucose levels and identify factors influencing the response to vitamin D intake. The results showed that vitamin D supplementation significantly protected glucose homeostasis, and the response to vitamin D may be influenced by basal vitamin D levels, VDR gene polymorphism, and metabolic profiles.
CLINICAL NUTRITION
(2023)
