MicroRNAs in Vascular and Metabolic Disease

Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity

(2011) S. Nagalla et al.   BLOOD

MicroRNA-126 modulates endothelial SDF-1 expression and mobilization of Sca-1+/Lin− progenitor cells in ischaemia

(2011) Coen van Solingen et al.   CARDIOVASCULAR RESEARCH

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

(2011) Leonardo Salmena et al.   CELL

The Lin28/let-7 Axis Regulates Glucose Metabolism

(2011) Hao Zhu et al.   CELL

MicroRNA-24 Regulates Vascularity After Myocardial Infarction

(2011) Jan Fiedler et al.   CIRCULATION

Flow-Dependent Regulation of Krüppel-Like Factor 2 Is Mediated by MicroRNA-92a

(2011) Wei Wu et al.   CIRCULATION

Proteomics

(2011) Marianna Prokopi et al.   CIRCULATION RESEARCH

MicroRNA-133 Controls Vascular Smooth Muscle Cell Phenotypic Switch In Vitro and Vascular Remodeling In Vivo

(2011) Daniele Torella et al.   CIRCULATION RESEARCH

Biogenesis and Regulation of Cardiovascular MicroRNAs

(2011) Johann Bauersachs et al.   CIRCULATION RESEARCH

Comparative Lipidomics Profiling of Human Atherosclerotic Plaques

(2011) Christin Stegemann et al.   Circulation-Cardiovascular Genetics

miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors

(2011) Tal Melkman-Zehavi et al.   EMBO JOURNAL

The miR-143/145 Cluster Is a Novel Transcriptional Target of Jagged-1/Notch Signaling in Vascular Smooth Muscle Cells

(2011) Joshua M. Boucher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Down-regulation of Krüppel-like Factor-4 (KLF4) by MicroRNA-143/145 Is Critical for Modulation of Vascular Smooth Muscle Cell Phenotype by Transforming Growth Factor-β and Bone Morphogenetic Protein 4

(2011) Brandi N. Davis-Dusenbery et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparison of different miR-21 inhibitor chemistries in a cardiac disease model

(2011) Thomas Thum et al.   JOURNAL OF CLINICAL INVESTIGATION

Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis

(2011) Katey J. Rayner et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes

(2011) Li Qian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of cardiovascular microRNA targetomes

(2011) J. Fiedler et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

MicroRNAs 103 and 107 regulate insulin sensitivity

(2011) Mirko Trajkovski et al.   NATURE

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

(2011) Katey J. Rayner et al.   NATURE

Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data

(2011) Chaolin Zhang et al.   NATURE BIOTECHNOLOGY

MicroRNAs can generate thresholds in target gene expression

(2011) Shankar Mukherji et al.   NATURE GENETICS

Silencing of microRNA families by seed-targeting tiny LNAs

(2011) Susanna Obad et al.   NATURE GENETICS

MicroRNA-21 Exhibits Antiangiogenic Function by Targeting RhoB Expression in Endothelial Cells

(2011) Céline Sabatel et al.   PLoS One

MicroRNA-21 targets peroxisome proliferators-activated receptor-  in an autoregulatory loop to modulate flow-induced endothelial inflammation

(2011) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of angiogenesis and choroidal neovascularization by members of microRNA-23 27 24 clusters

(2011) Q. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles for miRNA-378/378* in adipocyte gene expression and lipogenesis

(2010) Isabelle Gerin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Ets-1 and Ets-2 Regulate the Expression of MicroRNA-126 in Endothelial Cells

(2010) Tamia A. Harris et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MicroRNAs Are Necessary for Vascular Smooth Muscle Growth, Differentiation, and Function

(2010) Sebastian Albinsson et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

microRNA-222 Controls Neovascularization by Regulating Signal Transducer and Activator of Transcription 5A Expression

(2010) Patrizia Dentelli et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Signaling During Platelet Adhesion and Activation

(2010) Zhenyu Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Members of the microRNA-17-92 cluster exhibit a cell-intrinsic antiangiogenic function in endothelial cells

(2010) C. Doebele et al.   BLOOD

Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4

(2010) Y. Cheng et al.   CARDIOVASCULAR RESEARCH

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

(2010) Markus Hafner et al.   CELL

MicroRNAs Add a New Dimension to Cardiovascular Disease

(2010) Eric M. Small et al.   CIRCULATION

A miR-thless Perspective

(2010) Ralf P. Brandes   CIRCULATION RESEARCH

Short Communication: Asymmetric Dimethylarginine Impairs Angiogenic Progenitor Cell Function in Patients With Coronary Artery Disease Through a MicroRNA-21–Dependent Mechanism

(2010) Felix Fleissner et al.   CIRCULATION RESEARCH

Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes

(2010) Anna Zampetaki et al.   CIRCULATION RESEARCH

Two Functional MicroRNA-126s Repress a Novel Target Gene p21-Activated Kinase 1 to Regulate Vascular Integrity in Zebrafish

(2010) Jun Zou et al.   CIRCULATION RESEARCH

RISC RNA Sequencing for Context-Specific Identification of In Vivo MicroRNA Targets

(2010) Scot J. Matkovich et al.   CIRCULATION RESEARCH

Emerging Roles for Natural MicroRNA Sponges

(2010) Margaret S. Ebert et al.   CURRENT BIOLOGY

MicroRNA-27b Contributes to Lipopolysaccharide-mediated Peroxisome Proliferator-activated Receptor γ (PPARγ) mRNA Destabilization

(2010) Carla Jennewein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA control of podosome formation in vascular smooth muscle cells in vivo and in vitro

(2010) Manuela Quintavalle et al.   JOURNAL OF CELL BIOLOGY

The magic and mystery of miR-21

(2010) Edward E. Morrisey   JOURNAL OF CLINICAL INVESTIGATION

Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice

(2010) David M. Patrick et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-370 controls the expression of MicroRNA-122 and Cpt1α and affects lipid metabolism

(2010) Dimitrios Iliopoulos et al.   JOURNAL OF LIPID RESEARCH

Genome-wide Dissection of MicroRNA Functions and Cotargeting Networks Using Gene Set Signatures

(2010) John S. Tsang et al.   MOLECULAR CELL

MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis

(2010) Stefania Nicoli et al.   NATURE

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

miR-33 links SREBP-2 induction to repression of sterol transporters

(2010) T. J. Marquart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro

(2010) Y. Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis

(2010) S. H. Najafi-Shoushtari et al.   SCIENCE

MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

(2010) K. J. Rayner et al.   SCIENCE

microRNA-221 regulates high glucose-induced endothelial dysfunction

(2009) Yangxin Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The up-regulation of microRNA-335 is associated with lipid metabolism in liver and white adipose tissue of genetically obese mice

(2009) Noriko Nakanishi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures

(2009) M. Prokopi et al.   BLOOD

MicroRNA-125a is over-expressed in insulin target tissues in a spontaneous rat model of Type 2 Diabetes

(2009) Blanca M Herrera et al.   BMC Medical Genomics

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease

(2009) L Elia et al.   CELL DEATH AND DIFFERENTIATION

Reciprocal Regulation of Myocardial microRNAs and Messenger RNA in Human Cardiomyopathy and Reversal of the microRNA Signature by Biomechanical Support

(2009) Scot J. Matkovich et al.   CIRCULATION

MicroRNA-145, a Novel Smooth Muscle Cell Phenotypic Marker and Modulator, Controls Vascular Neointimal Lesion Formation

(2009) Yunhui Cheng et al.   CIRCULATION RESEARCH

A Necessary Role of miR-221 and miR-222 in Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia

(2009) Xiaojun Liu et al.   CIRCULATION RESEARCH

Redefining MicroRNA Targets

(2009) Hervé Seitz   CURRENT BIOLOGY

MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury

(2009) M. Xin et al.   GENES & DEVELOPMENT

New class of microRNA targets containing simultaneous 5'-UTR and 3'-UTR interaction sites

(2009) I. Lee et al.   GENOME RESEARCH

Ischemic Preconditioning Augments Survival of Stem Cells via miR-210 Expression by Targeting Caspase-8-associated Protein 2

(2009) Ha Won Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster

(2009) Thomas Boettger et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-24 Inhibits Cell Proliferation by Targeting E2F2, MYC, and Other Cell-Cycle Genes via Binding to “Seedless” 3′UTR MicroRNA Recognition Elements

(2009) Ashish Lal et al.   MOLECULAR CELL

Existence of a microRNA pathway in anucleate platelets

(2009) Patricia Landry et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Labeled microRNA pull-down assay system: an experimental approach for high-throughput identification of microRNA-target mRNAs

(2009) Ren-Jun Hsu et al.   NUCLEIC ACIDS RESEARCH

miR-375 maintains normal pancreatic  - and  -cell mass

(2009) M. N. Poy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice

(2009) A. Bonauer et al.   SCIENCE

Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs

(2008) Pascal Lovis et al.   BIOLOGICAL CHEMISTRY

Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters

(2008) Andrea Ventura et al.   CELL

Proteomics Identifies Thymidine Phosphorylase As a Key Regulator of the Angiogenic Potential of Colony-Forming Units and Endothelial Progenitor Cell Cultures

(2008) Giordano Pula et al.   CIRCULATION RESEARCH

Metabolomics

(2008) Manuel Mayr   Circulation-Cardiovascular Genetics

miR-126 Regulates Angiogenic Signaling and Vascular Integrity

(2008) Jason E. Fish et al.   DEVELOPMENTAL CELL

The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis

(2008) Shusheng Wang et al.   DEVELOPMENTAL CELL

miR-375 Targets 3'-Phosphoinositide-Dependent Protein Kinase-1 and Regulates Glucose-Induced Biological Responses in Pancreatic  -Cells

(2008) A. El Ouaamari et al.   DIABETES

Alterations in MicroRNA Expression Contribute to Fatty Acid-Induced Pancreatic  -Cell Dysfunction

(2008) P. Lovis et al.   DIABETES

Hypoxia induces microRNA miR-210 in vitro and in vivo

(2008) Kati Pulkkinen et al.   FEBS LETTERS

microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart

(2008) N. Liu et al.   GENES & DEVELOPMENT

MicroRNA-210 Modulates Endothelial Cell Response to Hypoxia and Inhibits the Receptor Tyrosine Kinase Ligand Ephrin-A3

(2008) Pasquale Fasanaro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction of MicroRNA-221 by Platelet-derived Growth Factor Signaling Is Critical for Modulation of Vascular Smooth Muscle Phenotype

(2008) Brandi N. Davis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-10a Binds the 5′UTR of Ribosomal Protein mRNAs and Enhances Their Translation

(2008) Ulf Andersson Ørom et al.   MOLECULAR CELL

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE

SMAD proteins control DROSHA-mediated microRNA maturation

(2008) Brandi N. Davis et al.   NATURE

LNA-mediated microRNA silencing in non-human primates

(2008) Joacim Elmén et al.   NATURE

Systematic Identification of mRNAs Recruited to Argonaute 2 by Specific microRNAs and Corresponding Changes in Transcript Abundance

(2008) David G. Hendrickson et al.   PLoS One

Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis

(2008) Y. Suarez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1

(2008) T. A. Harris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA