Phenotypical Manifestations of Mutations in the Genes Encoding Subunits of the Cardiac Sodium Channel

Functional dominant-negative mutation of sodium channel subunit gene SCN3B associated with atrial fibrillation in a Chinese GeneID population

(2010) Pengyun Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Trafficking Defects and Gating Abnormalities of a Novel SCN5A Mutation Question Gene-Specific Therapy in Long QT Syndrome Type 3

(2010) Yanfei Ruan et al.   CIRCULATION RESEARCH

Genetics of Brugada syndrome

(2010) Oscar Campuzano et al.   CURRENT OPINION IN CARDIOLOGY

Genetics and cardiac channelopathies

(2010) Oscar Campuzano et al.   GENETICS IN MEDICINE

Sudden infant death syndrome–associated mutations in the sodium channel beta subunits

(2010) Bi-Hua Tan et al.   HEART RHYTHM

Exercise extreme caution when calling rare genetic variants novel arrhythmia syndrome susceptibility mutations

(2010) Arthur A.M. Wilde et al.   HEART RHYTHM

GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A

(2009) Carmen R. Valdivia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Gain-of-function mutation of Na v 1.5 in atrial fibrillation enhances cellular excitability and lowers the threshold for action potential firing

(2009) Qiuju Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Loss-of-function mutation of the SCN3B-encoded sodium channel  3 subunit associated with a case of idiopathic ventricular fibrillation

(2009) C. R. Valdivia et al.   CARDIOVASCULAR RESEARCH

Genetic Testing for Long-QT Syndrome

(2009) Suraj Kapa et al.   CIRCULATION

Genetically Determined Differences in Sodium Current Characteristics Modulate Conduction Disease Severity in Mice With Cardiac Sodium Channelopathy

(2009) Carol Ann Remme et al.   CIRCULATION RESEARCH

α1-Syntrophin Mutations Identified in Sudden Infant Death Syndrome Cause an Increase in Late Cardiac Sodium Current

(2009) Jianding Cheng et al.   Circulation-Arrhythmia and Electrophysiology

Mutations in Sodium Channel β1- and β2-Subunits Associated With Atrial Fibrillation

(2009) Hiroshi Watanabe et al.   Circulation-Arrhythmia and Electrophysiology

SCN5A Mutations and the Role of Genetic Background in the Pathophysiology of Brugada Syndrome

(2009) Vincent Probst et al.   Circulation-Cardiovascular Genetics

A Mutation in the β3 Subunit of the Cardiac Sodium Channel Associated With Brugada ECG Phenotype

(2009) Dan Hu et al.   Circulation-Cardiovascular Genetics

Genetics of familial atrial fibrillation

(2009) O. Campuzano et al.   EUROPACE

An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing

(2009) Jamie D. Kapplinger et al.   HEART RHYTHM

Genetic Modulation of Brugada Syndrome by a Common Polymorphism

(2009) ERIC LIZOTTE et al.   JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY

Cardiac sodium channel Nav1.5 and interacting proteins: Physiology and pathophysiology

(2009) Hugues Abriel   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardiac sodium channelopathies

(2009) Ahmad S. Amin et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Regulation of caveolar cardiac sodium current by a single Gsα histidine residue

(2008) Oleg A. Palygin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cardiac Sodium Channel ( SCN5A ) Variants Associated with Atrial Fibrillation

(2008) Dawood Darbar et al.   CIRCULATION

α-1-Syntrophin Mutation and the Long-QT Syndrome

(2008) Geru Wu et al.   Circulation-Arrhythmia and Electrophysiology

A mutation in the sodium channel is responsible for the association of long QT syndrome and familial atrial fibrillation

(2008) Begoña Benito et al.   HEART RHYTHM

Type of SCN5A mutation determines clinical severity and degree of conduction slowing in loss-of-function sodium channelopathies

(2008) Paola G. Meregalli et al.   HEART RHYTHM

LQT3: Who is at risk for sudden cardiac death?

(2008) Lars Eckardt   HEART RHYTHM

Ranolazine Shortens Repolarization in Patients with Sustained Inward Sodium Current Due to Type-3 Long-QT Syndrome

(2008) ARTHUR J. MOSS et al.   JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY

Voltage-gated Navchannel targeting in the heart requires an ankyrin-G–dependent cellular pathway

(2008) John S. Lowe et al.   JOURNAL OF CELL BIOLOGY

A Novel SCN5A Gain-of-Function Mutation M1875T Associated With Familial Atrial Fibrillation

(2008) Takeru Makiyama et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex

(2008) K. Ueda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SCN5A channelopathies – An update on mutations and mechanisms

(2008) Thomas Zimmer et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Cardiac Sodium Channel Overlap Syndromes: Different Faces of SCN5A Mutations

(2008) Carol Ann Remme et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Cardiac sodium channel mutation in atrial fibrillation

(2007) Patrick T. Ellinor et al.   HEART RHYTHM