Orai1 and CRAC Channel Dependence of VEGF-Activated Ca 2+ Entry and Endothelial Tube Formation

Depletion of Intracellular Ca 2+ Stores Stimulates the Translocation of Vanilloid Transient Receptor Potential 4-C1 Heteromeric Channels to the Plasma Membrane

(2010) Xin Ma et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

TRPC1 Is Essential for In Vivo Angiogenesis in Zebrafish

(2010) Peng-chun Yu et al.   CIRCULATION RESEARCH

STIM1-dependent and STIM1-independent Function of Transient Receptor Potential Canonical (TRPC) Channels Tunes Their Store-operated Mode

(2010) Kyu Pil Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases

(2010) Yihai Cao   NATURE REVIEWS DRUG DISCOVERY

The endothelial cell tube formation assay on basement membrane turns 20: state of the science and the art

(2009) Irina Arnaoutova et al.   ANGIOGENESIS

Critical role of TRPC6 channels in VEGF-mediated angiogenesis

(2009) Ruiliang Ge et al.   CANCER LETTERS

Human Studies of Angiogenic Gene Therapy

(2009) Rajesh Gupta et al.   CIRCULATION RESEARCH

TRPV4 Channels Mediate Cyclic Strain–Induced Endothelial Cell Reorientation Through Integrin-to-Integrin Signaling

(2009) Charles K. Thodeti et al.   CIRCULATION RESEARCH

ORAI1 and STIM1 deficiency in human and mice: roles of store-operated Ca2+entry in the immune system and beyond

(2009) Stefan Feske   IMMUNOLOGICAL REVIEWS

ORAI1 deficiency and lack of store-operated Ca2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia

(2009) Christie-Ann McCarl et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Increased Hydrophobicity at the N Terminus/Membrane Interface Impairs Gating of the Severe Combined Immunodeficiency-related ORAI1 Mutant

(2009) Isabella Derler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting Gut T Cell Ca2+ Release-Activated Ca2+ Channels Inhibits T Cell Cytokine Production and T-Box Transcription Factor T-Bet in Inflammatory Bowel Disease

(2009) A. Di Sabatino et al.   JOURNAL OF IMMUNOLOGY

Endothelial progenitor cells - hype or hope?

(2009) J. D. PEARSON   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

STIMulating store-operated Ca2+ entry

(2009) Michael D. Cahalan   NATURE CELL BIOLOGY

STIM1 gates the store-operated calcium channel ORAI1 in vitro

(2009) Yubin Zhou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

R93W mutation in Orai1 causes impaired calcium influx in platelets

(2008) W. Bergmeier et al.   BLOOD

Stim1 and Orai1 Mediate CRAC Currents and Store-Operated Calcium Entry Important for Endothelial Cell Proliferation

(2008) Iskandar F. Abdullaev et al.   CIRCULATION RESEARCH

Sustained Activation of the Tyrosine Kinase Syk by Antigen in Mast Cells Requires Local Ca2+Influx through Ca2+Release-activated Ca2+Channels

(2008) Siaw Wei Ng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VEGF-Mediated Elevated Intracellular Calcium and Angiogenesis in Human Microvascular Endothelial CellsIn Vitroare Inhibited by Dominant Negative TRPC6

(2008) M.A. Hamdollah Zadeh et al.   MICROCIRCULATION

Hair Loss and Defective T- and B-Cell Function in Mice Lacking ORAI1

(2008) Y. Gwack et al.   MOLECULAR AND CELLULAR BIOLOGY

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE