Article
Medicine, General & Internal
Rutger W. M. Brouwers, Esmee K. J. van der Poort, Hareld M. C. Kemps, M. Elske van den Akker-van Marle, Jos J. Kraal
Summary: This study compared the cost-effectiveness of cardiac telerehabilitation (CTR) with relapse prevention to traditional center-based cardiac rehabilitation (CR) among patients with coronary artery disease. The results suggest that CTR may be a cost-effective alternative intervention for the treatment of these patients, potentially increasing its implementation in clinical practice.
Article
Biology
Razvan Anghel, Cristina Andreea Adam, Dragos Traian Marius Marcu, Ovidiu Mitu, Mihai Roca, Grigore Tinica, Florin Mitu
Summary: This study assessed factors associated with clinical improvement in patients with peripheral artery disease (PAD) undergoing a rehabilitation program at an academic medical center in north-eastern Europe. The results showed that smoking cessation, changing sedentary lifestyle, and improvement in lipid and carbohydrate profile, as well as functional status parameters, were associated with clinical improvement at the 6-months follow-up. This study highlights the importance of an integrative, multidisciplinary management approach in maintaining functional status and improving quality of life in PAD patients.
Article
Orthopedics
Sally L. Wootton, Marita T. Dale, Jennifer A. Alison, Sarah Brown, Hannah Rutherford, Andrew S. L. Chan, Marlien Varnfield, Ian A. Yang, Michelle Cunich, Sarah Dennis, Zoe J. McKeough
Summary: This study aims to determine if a home-based pulmonary rehabilitation program supported by mobile health technology is equivalent to center-based pulmonary rehabilitation in terms of improvements in exercise capacity and health status in people with COPD. It is a prospective, multicenter, equivalence randomized controlled trial with intention-to-treat analysis, and it will provide important evidence for the feasibility of promoting pulmonary rehabilitation programs.
Article
Surgery
Pasha Normahani, David M. Epstein, Alessio Gaggero, Alun H. Davies, Viknesh Sounderajah, Usman Jaffer
Summary: This study evaluated the cost-effectiveness of point-of-care duplex ultrasound (PAD-scan) and other bedside tests for diagnosing peripheral arterial disease (PAD) in patients with diabetes. The results showed that PAD-scan was the most cost-effective bedside test, reducing the occurrence of amputations and cardiovascular deaths.
Review
Sport Sciences
Jane Fonseca Dias, Vinicius Cunha Oliveira, Pollyana Ruggio Tristao Borges, Fabiana Caetano Martins Silva Dutra, Marisa Cotta Mancini, Renata Noce Kirkwood, Renan Alves Resende, Rosana Ferreira Sampaio
Summary: Exercise-based telerehabilitation showed no significant difference compared to other interventions in improving pain, physical function, and quality of life in adults with physical disabilities in the long term. However, in the short term, there was some difference, but due to limited evidence and trials, the efficacy of telerehabilitation on these outcomes cannot be definitively stated.
BRITISH JOURNAL OF SPORTS MEDICINE
(2021)
Article
Rehabilitation
Eva Torbjornsson, Carin Ottosson, Lennart Bostrom, Lena Blomgren, Jonas Malmstedt, Ann-Mari Fagerdahl
Summary: This study aimed to compare the health-related quality of life (HRQoL) between walker and non-walker amputees, as well as evaluate prosthesis use and habits. The results showed that patients walking with a prosthesis had improved HRQoL at follow-up. Independent movement was also found to be important for improving HRQoL.
DISABILITY AND REHABILITATION
(2022)
Article
Cardiac & Cardiovascular Systems
Zeljko Reiner, Johan De Sutter, Lars Ryden, Erkin Mirrakhimov, Nana Pogosova, Marina Dolzhenko, Zlatko Fras, Kornelia Kotseva, David Wood, Dirk De Bacquer
Summary: This study investigated the prevalence of PAD and suspected PAD in CHD patients, finding that PAD patients had worse risk factor profiles and lower health-related quality of life.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Farzin Fakhry, Ellen Rouwet, Reinier Spillenaar Bilgen, Lijckle van der Laan, Jan J. Wever, Joep A. W. Teijink, Wolter H. Hoffmann, Andre van Petersen, Jerome P. van Brussel, Guido N. M. Stultiens, Alex Derom, P. Ted den Hoed, Gwan H. Ho, Lukas C. van Dijk, Nicole Verhofstad, Mariella Orsini, Ingrid Hulst, Marc R. H. M. van Sambeek, Dimitris Rizopoulos, Adriaan Moelker, M. G. Myriam Hunink
Summary: The ERASE study demonstrated that a combination therapy of endovascular revascularization followed by supervised exercise is more effective in improving walking ability and quality of life for patients with intermittent claudication, and is cost-effective compared to supervised exercise alone. However, further research is needed to define the long-term cost and clinical effectiveness of both strategies for specific patient groups.
CIRCULATION-CARDIOVASCULAR INTERVENTIONS
(2021)
Article
Peripheral Vascular Disease
Jiali Fan, Wanji Zheng, Wei Liu, Juan Xu, Lan Zhou, Shihe Liu, JingJing Bai, Yue Qi, Weidong Huang, Kejun Liu, Jun Cai
Summary: This study compared the health benefits and costs of intensive blood pressure treatment with standard treatment in older hypertensive patients. The simulation results showed that intensive treatment prevented cardiovascular events and was cost-effective in most scenarios.
Review
Cardiac & Cardiovascular Systems
Saul Penin-Grandes, Susana Lopez-Ortiz, Sergio Maroto-Izquierdo, Hector Menendez, Jose Pinto-Fraga, Juan Martin-Hernandez, Simone Lista, Alejandro Lucia, Alejandro Santos-Lozano
Summary: This systematic review evaluates the effects of regular exercise in patients with peripheral arterial disease (PAD) by summarizing published meta-analyses. The review finds that exercise has a positive impact on functional parameters and health-related quality of life in PAD patients. Supervised aerobic exercise is particularly effective in improving walking-related outcomes and pain, while resistance exercise is more effective for improving lower limb strength.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Health Care Sciences & Services
Aurelie Durufle, Claire Le Meur, Patrice Piette, Bastien Fraudet, Emilie Leblong, Philippe Gallien
Summary: This study compared the economic benefits of face-to-face care and remote care for neurological patients. The results showed that remote care is an acceptable alternative for managing neurological patients at home, and may even be advantageous in milder cases. Further extensive studies are needed to specify the indications.
Article
Medicine, General & Internal
Hildigunnur Ulfsdottir, Maria Back, Asa Cider, Lennart Jivegard, Anna Sandberg, Joakim Nordanstig, Mikael Svensson
Summary: Hospital-based supervised exercise (SEP) is not cost-effective for patients with intermittent claudication (IC) compared to walk advice (WA) with or without home-based structured exercise programs (HSEP). Although the average healthcare cost per patient was similar between WA and HSEP groups, it was significantly higher in the SEP group. The findings suggest that HSEP may have a higher probability of being cost-effective compared to WA, but further research is needed.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Agnieszka Wachsmann-Maga, Mikolaj Maga, Romuald Polczyk, Aleksandra Wlodarczyk, Patrycja Pasieka, Karol Terlecki, Pawel Maga
Summary: This study aimed to assess the dependence between vascular inflammation and quality of life in patients with peripheral arterial disease. It found a negative correlation between prostaglandin concentrations and life quality.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Rehabilitation
Maria Lopez-Garzon, Irene Cantarero-Villanueva, Paula Postigo-Martin, Angela Gonzalez-Santos, Mario Lozano-Lozano, Noelia Galiano-Castillo
Summary: This systematic review analyzed the effects of physical exercise programs in patients with cancer undergoing chemotherapy on chemo-therapy-induced peripheral neuropathy (CIPN) prevention. The review found that physical exercise at the onset of chemotherapy has promising effects on the prevention of CIPN and can improve the quality of life.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Multidisciplinary Sciences
Shalika Bohingamu Mudiyanselage, Jo Stevens, Julian Toscano, Mark A. Kotowicz, Christopher L. Steinfort, Robyn Hayles, Jennifer J. Watts
Summary: The study evaluates the cost-effectiveness of a personalised telehealth intervention for managing chronic diseases in the long term. The pilot study compared the costs and effectiveness of telehealth monitoring with usual care and found that the intervention resulted in a significant improvement in health-related quality of life at an additional cost per patient. The study suggests that offering the program to a larger population may be necessary to achieve cost-effectiveness.
Article
Peripheral Vascular Disease
Francisco Jose Rodriguez-Cortes, Jorge E. Jimenez-Hornero, Juan Francisco Alcala-Diaz, Francisco Jose Jimenez-Hornero, Juan Luis Romero-Cabrera, Rosaria Cappadona, Roberto Manfredini, Pablo Jesus Lopez-Soto
Summary: The present study investigated the impact of daylight saving time (DST) transitions on the incidence of hospital admissions for major acute cardiovascular events (MACE). Using natural visibility graphs (NVGs) and data from Andalusian public hospitals between 2009 and 2019, the study found a slight increase in the risk of heart attacks after DST transitions, but this increase did not significantly alter the overall pattern of hospital admissions.
Article
Biochemistry & Molecular Biology
Giovanni Piva, Anna Crepaldi, Nicola Lamberti, Lorenzo Caruso, Natascia Rinaldo, Roberto Manfredini, Pablo Jesus Lopez-Soto, Vincenzo Gasbarro, Fabio Manfredini, Alda Storari
Summary: This observational study aimed to monitor the 5-year trends of kidney function in patients with peripheral artery disease (PAD) and concomitant chronic kidney disease (CKD) enrolled or not enrolled into a rehabilitative exercise program. The results showed that patients in the exercise program had improved kidney function and better clinical outcomes compared to those receiving usual care.
Article
Sport Sciences
Natascia Rinaldo, Giovanni Piva, Suzanne Ryder, Anna Crepaldi, Alba Pasini, Lorenzo Caruso, Roberto Manfredini, Sofia Straudi, Fabio Manfredini, Nicola Lamberti
Summary: Despite progress, gender bias still exists in scientific publication authorship. This study examines trends in authorship by gender in the field of exercise sciences and rehabilitation in the last 5 years. The results show that while women are almost equally represented as first authors, bias against women remains in the last authorship position, regardless of geographical area and journal ranking.
JOURNAL OF FUNCTIONAL MORPHOLOGY AND KINESIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Valeria Raparelli, Giulio Francesco Romiti, Giulia Di Teodoro, Ruggiero Seccia, Gaetano Tanzilli, Nicola Viceconte, Ramona Marrapodi, Davide Flego, Bernadette Corica, Roberto Cangemi, Louise Pilote, Stefania Basili, Marco Proietti, Laura Palagi, Lucia Stefanin
Summary: A machine-learning model was developed to predict obstructive versus non-obstructive coronary artery disease (CAD). By analyzing various features including age, biomarkers, and social characteristics, the model achieved a high accuracy and precision in discriminating between the two types of CAD.
CLINICAL RESEARCH IN CARDIOLOGY
(2023)
Article
Health Care Sciences & Services
Nicola Lamberti, Luca Traina, Caterina Savrie, Elpiniki Tsolaki, Natascia Rinaldo, Sofia Straudi, Franco Guerzoni, Nicola Napoli, Roberto Manfredini, Vincenzo Gasbarro, Fabio Manfredini
Summary: This study evaluated the sex-specific difference in response to an exercise program among patients with peripheral artery disease and claudication. The results showed that women had a significantly higher 7-year survival rate and lower hospitalization and amputation rates in the exercise group compared to the control group. Therefore, active participation in a home-based pain-free exercise program can reduce the risk of adverse clinical outcomes and improve long-term outcomes, especially for women in PAD patients.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Health Care Sciences & Services
Alessandro Borghi, Maria Elena Flacco, Lucrezia Pacetti, Gionathan Orioni, Elisa Marzola, Rosario Cultrera, Valentina Guerra, Roberto Manfredini, Valeria Gaspari, Daniela Segala, Monica Corazza
Summary: There is no evidence of seasonal variation in visits to STI clinics in Italy, nor of changes after the advent of the COVID-19 pandemic. A multicentric study recorded and analyzed visits to STI clinics in Italy between January 2016 and November 2021, and found a significant decrease in monthly visits during the pandemic compared to before. Visits to STI clinics increased during autumn/winter in the pre-pandemic period, but this trend was reversed during the pandemic.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Nursing
Pablo Jesus Lopez-Soto, Francisco Jose Rodriguez-Cortes, Rosa Maria Minarro-Del Moral, Maria Jose Medina-Valverde, Rocio Segura-Ruiz, Pedro Hidalgo-Lopezosa, Roberto Manfredini, Maria Aurora Rodriguez-Borrego
Summary: The study aimed to reduce in-hospital falls by implementing a nurse-led intervention based on the temporal patterns and causes of falls. Through longitudinal prospective and retrospective studies, as well as qualitative analysis, it was found that the implementation of this intervention led to a decrease in the number of falls among hospitalized patients.
Letter
Medicine, General & Internal
Pasquale Agosti, Alessio Novella, Carlo Custodero, Chiara Elli, Luca Pasina
EUROPEAN JOURNAL OF INTERNAL MEDICINE
(2023)
Article
Health Care Sciences & Services
Anna Crepaldi, Lorenzo Caruso, Giovanni Piva, Luca Traina, Vincenzo Gasbarro, Roberto Manfredini, Nicola Lamberti, Natascia Rinaldo, Fabio Manfredini, Pablo Jesus Lopez-Soto
Summary: This study aimed to detect foot perfusion changes in PAD patients after a home-based exercise program using infrared thermography. The results showed that after 20 weeks of exercise, foot temperature in both limbs significantly increased, with no significant difference between genders. Additionally, the ankle brachial index and performance also significantly improved over time.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Sport Sciences
Natascia Rinaldo, Alba Pasini, Sofia Straudi, Giovanni Piva, Anna Crepaldi, Andrea Baroni, Lorenzo Caruso, Fabio Manfredini, Nicola Lamberti
Summary: People with multiple sclerosis (pwMS) experience decreased bone mineral density and worsening body composition, negatively impacting their quality of life. This systematic review and meta-analysis examined the effects of nonpharmacological interventions, such as physical activity, nutrition, and rehabilitation, on body composition (BC) and bone mineral density (BMD) in pwMS. The results showed inconsistent positive effects on BC, but high-intensity training and ketogenic diets appeared to be promising interventions. Limited studies considered BMD, and the findings were inconclusive. Further research is needed to confirm these results.
JOURNAL OF FUNCTIONAL MORPHOLOGY AND KINESIOLOGY
(2023)
Article
Pharmacology & Pharmacy
F. J. Rodriguez-Cortes, J. E. Jimenez-Hornero, J. F. Alcala-Diaz, R. M. Minarro-del Moral, J. L. Romero-Cabrera, R. Manfredini, M. A. Rodriguez-Borrego, P. J. Lopez-Soto
Summary: The study aimed to determine the impact of the COVID-19 pandemic on hospital admissions for acute myocardial infarction (AMI) and cerebrovascular disease (CVD) in Andalusia, Spain, and analyzed gender and procedural differences. The results showed significant reductions in daily hospital admissions for AMI and CVD during the pandemic. Gender differences were observed, but no significant impact was found in percutaneous coronary interventions.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2023)
Article
Pharmacology & Pharmacy
A. Rizza, A. DE Giorgi, F. Negro, B. Boari, C. Palmieri, S. Berti, R. Manfredini
Summary: The objective of this study was to investigate chronobiological patterns and sex-specific differences among acute myocardial infarction (AMI) patients in Italy. The results showed that factors independently associated with in-hospital death included female sex, age, history of ischemic heart disease, and night-time interventional procedure. The study also found that there was a higher peak of AMI events in summer, while in-hospital mortality rate was higher in winter.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2023)
Article
Respiratory System
Nicola Lamberti, Giovanni Piva, Yuri Battaglia, Michele Franchi, Matteo Pizzolato, Antonio Argentoni, Giorgio Gandolfi, Giulia Gozzi, Margherita Lembo, Pietro Lavisci, Alda Storari, Natascia Rinaldo, Fabio Manfredini, Annalisa Cogo
Summary: This study aimed to investigate the feasibility and effectiveness of low-intensity respiratory muscle training in end-stage kidney disease patients. The results showed that home-based RMT significantly improved respiratory muscle strength in patients.
ADVANCES IN RESPIRATORY MEDICINE
(2023)
Article
Health Care Sciences & Services
Alessandro Borghi, Alfredo De Giorgi, Alberto Monti, Rosaria Cappadona, Roberto Manfredini, Monica Corazza
Summary: This study investigated the chronotype and sleep quality of Italian psoriatic patients and found that sleep disturbance is common in these patients, especially in those with comorbidities, females, and those who live alone.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
