Article
Cardiac & Cardiovascular Systems
Francesco Saverio Mennini, Francesco Meucci, Gabriele Pesarini, Pietro Vandoni, Maddalena Lettino, Archita Sarmah, Judith Shore, Michelle Green, Stefano Giardina
Summary: This cost-utility analysis showed that TAVI with SAPIEN 3 is likely to be cost effective compared with SAVR for the treatment of low-risk sSAS patients.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Review
Medicine, General & Internal
Lola Gutierrez, Mauro Boiago, Chiara De Biase, Omar Oliva, Pietro Laforgia, Souheib Feliachi, Alessandro Beneduce, Nicolas Dumonteil, Didier Tchetche
Summary: Bicuspid aortic valve disease is the most common congenital heart disease, associated with unique morphological features and lack of consensus in sizing measurement. Multi-slice computed tomography plays a crucial role in TAVI procedure planning, and advancements in devices and procedure planning have improved clinical outcomes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Flavien Vincent, Julien Ternacle, Tom Denimal, Mylene Shen, Bjorn Redfors, Cedric Delhaye, Matheus Simonato, Nicolas Debry, Basile Verdier, Bahira Shahim, Thibault Pamart, Hugues Spillemaeker, Guillaume Schurtz, Francois Pontana, Vinod H. Thourani, Philippe Pibarot, Eric Van Belle
Summary: TAVR is rapidly expanding its indications, but faces technical challenges and knowledge gaps when dealing with patients with bicuspid aortic valve (BAV). Physicians need to understand the BAV anatomy and TAVR procedure planning comprehensively to guide treatment decisions.
Article
Medicine, General & Internal
Samir R. R. Kapadia, Raj Makkar, Martin Leon, Mohamed Abdel-Wahab, Thomas Waggoner, Steffen Massberg, Wolfgang Rottbauer, Samuel Horr, Lars Sondergaard, Juhana Karha, Robert Gooley, Lowell Satler, Robert C. Stoler, Steven R. Messe, Suzanne J. Baron, Julia Seeger, Susheel Kodali, Amar Krishnaswamy, Vinod H. Thourani, Katherine Harrington, Stuart Pocock, Rodrigo Modolo, Dominic J. Allocco, Ian T. Meredith, Axel Linke, PROTECTED TAVR Investigators
Summary: Among patients with aortic stenosis undergoing transfemoral TAVR, the use of CEP did not have a significant effect on the incidence of periprocedural stroke, but on the basis of the 95% confidence interval around this outcome, the results may not rule out a benefit of CEP during TAVR.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Tadeja Kolar, Nikola Lakic, Alesa Kotnik, David Stubljar, Zlatko Fras, Matjaz Bunc
Summary: This study compared the outcomes of transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) in octogenarians. The results showed similar clinical outcomes in terms of clinical endpoints in low- and medium-risk groups, but differences were observed in certain indicators such as paravalvular leak, acute kidney injury, and new onset atrial fibrillation.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Hans-Josef Feistritzer, Thomas Kurz, Georg Stachel, Philipp Hartung, Philipp Lurz, Ingo Eitel, Christoph Marquetand, Holger Nef, Oliver Doerr, Ursula Vigelius-Rauch, Alexander Lauten, Ulf Landmesser, Sascha Treskatsch, Mohamed Abdel-Wahab, Marcus Sandri, David Holzhey, Michael Borger, Jorg Ender, Huseyin Ince, Alper Oener, Roza Meyer-Saraei, Rainer Hambrecht, Harm Wienbergen, Andreas Fach, Thomas Augenstein, Norbert Frey, Inke R. Koenig, Reinhard Vonthein, Anne-Kathrin Funkat, Astrid E. Berggreen, Matthias Heringlake, Steffen Desch, Suzanne De Waha-Thiele, Holger Thiele
Summary: This study compared the clinical outcomes of patients undergoing transfemoral TAVR with different valve types and anesthetic methods at 1-year follow-up, demonstrating that there were no significant differences in outcomes between newer-generation SEV and BEV, as well as CS and GA.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Medicine, General & Internal
Melissa Y. Y. Moey, Kunjan Udani, L. Wiley Nifong, Blase A. Carabello, D. Lynn Morris, Neeraj N. Shah
Summary: This single-center retrospective study compared antiplatelet/antithrombotic therapy strategies after transcatheter aortic valve replacement (TAVR) and found that dual antiplatelet therapy (DAPT) had a higher incidence of 1-year death or ischemia compared to single antiplatelet therapy (SAPT), while oral anticoagulation (OAC) was associated with higher rates of major bleeding, especially late bleeding. These findings suggest the need for careful consideration of antiplatelet/antithrombotic therapy selection following TAVR.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2023)
Review
Economics
Phatcharaphorn Chotnoppharatphatthara, Voratima Yoodee, Suthinee Taesotikul, Jirawit Yadee, Unchalee Permsuwan
Summary: This study systematically reviewed the economic evaluation of transcatheter aortic valve implantation (TAVI) compared with alternative treatments in patients with severe aortic stenosis. The results showed that TAVI is a cost-effective alternative for patients with operable aortic stenosis, with gains in quality-adjusted life-years compared to surgical aortic valve replacement or medical management. The cost-effectiveness of TAVI depends on the acceptable threshold in each country.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2023)
Article
Cardiac & Cardiovascular Systems
Miho Fukui, Vinayak N. Bapat, Santiago Garcia, Marshall W. Dworak, Go Hashimoto, Hirotomo Sato, Mario Gossl, Maurice Enriquez-Sarano, John R. Lesser, Joao L. Cavalcante, Paul Sorajja
Summary: This study found that frame deformation, asymmetric leaflet, and smaller neosinus volume are associated with the occurrence of HALT in patients undergoing TAVR. The presence of HALT is associated with an increased risk of mortality within 1 year.
Article
Medicine, General & Internal
Yi-Ming Li, Tian-Yuan Xiong, Kai Xu, Zhen-Fei Fang, Lei Jiang, Jun Jin, Sheng-Hu He, Yi-Ning Yang, Jing-Jing He, Yu-Heng Jia, Yi Zhang, Yong Peng, Yuan Feng, Mao Chen
Summary: This study delineated the clinical characteristics and outcomes of Chinese TAVR patients, finding that TAVR candidates in China had lower rates of complications and mortality compared to other international registries, and patients with BAV had lower mortality rates. These results suggest that the application of TAVR in low-risk patients will be further propelled.
CHINESE MEDICAL JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Michael J. Reardon, Bassem Chehab, Dave Smith, Antony S. Walton, Stephen G. Worthley, Ganesh Manoharan, Ibrahim Sultan, Gerald Yong, Katherine Harrington, Paul Mahoney, Neal Kleiman, Raj R. Makkar, Gregory Fontana, Augustin DeLago, Ravi K. Ramana, Nicholas Bates, Lars Sondergaard
Summary: The PORTICO NG study evaluated the safety and effectiveness of the Navitor valve in high-risk patients with severe aortic stenosis. The results showed that the Navitor valve is safe and effective for treating severe aortic stenosis, with low rates of adverse events and paravalvular leak.
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Cardiac & Cardiovascular Systems
Riyad Y. Kherallah, Darren Harrison, Ourania Preventza, Guilherme Silva, Kathryn G. Dougherty, Stephanie A. Coulter, Leo Simpson, Neil E. Strickman, Ali Mortazavi, Nicolas Palaskas, Richard D. Fish, Zvonimir Krajcer, Raymond F. Stainback, Juan Carlos Plana Gomez, James J. Livesay, Joseph S. Coselli, Srikanth Koneru
Summary: This retrospective study examined 1341 patients who underwent TAVR, with 50 having a history of CRT. The study found that TAVR is safe and effective for patients with aortic valve stenosis and previous CRT, with outcomes similar to the general aortic stenosis population. However, patients with a history of CRT are more likely to experience postprocedural respiratory failure and require permanent pacemaker implantation.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Andreas Habertheuer, Edgar Aranda-Michel, John Schindler, Thomas G. Gleason, Arman Kilic, Dustin Kliner, Valentino Bianco, Catalin Toma, Ibrahim Sultan
Summary: The study found that TAVR can be performed safely in nonagenarians, with comparable outcomes to younger patients approximating natural life expectancy. This age paradox should strengthen the role of TAVR in well-selected nonagenarians by the heart team.
ANNALS OF THORACIC SURGERY
(2021)
Article
Medicine, General & Internal
Guannan Niu, Walid Ben Ali, Moyang Wang, Hasan Jilaihawi, Haitong Zhang, Qian Zhang, Yunqing Ye, Xinmin Liu, Jing Yao, Qinghao Zhao, Yubin Wang, Zheng Zhou, Lizhi Zhang, Xinshuang Ren, Yunqiang An, Bin Lu, Thomas Modine, Yongjian Wu, Guangyuan Song
Summary: Chinese patients who undergo TAVR for severe AS often have bicuspid aortic valve and a larger volume of calcium in the aortic root. Downsize strategy for patients with complex morphology provides similar device success rate and hemodynamic performance compared to annular sizing strategy.
CHINESE MEDICAL JOURNAL
(2022)
Article
Surgery
Michael P. Rogers, Haroon Janjua, Emanuel Eguia, Lucian Lozonschi, Paul C. Kuo
Summary: This study evaluated the adoption of transcatheter aortic valve replacement technology in surgical aortic valve procedures in Florida. The findings showed that the introduction of transcatheter aortic valve replacement significantly increased the overall surgical volume and may be associated with lower hospital charges.