Article
Medicine, General & Internal
Reka Skoda, Attila Nemes, Gyorgy Barczi, Hajnalka Vago, Zoltan Ruzsa, Istvan F. Edes, Attila Olah, Annamaria Kosztin, Elek Dinya, Bela Merkely, David Becker
Summary: This study aimed to assess the impact of diabetes mellitus (DM) on the clinical outcome and survival of patients with myocardial infarction (MI) who underwent percutaneous coronary intervention (PCI). The results showed that diabetic patients had worse short- and long-term survival compared to non-diabetic patients. The presence of DM was found to be more important than the type of MI in affecting survival, while LV and renal functions had a greater impact on survival than DM.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Endocrinology & Metabolism
Pil Sang Song, Kye Taek Ahn, Mi Joo Kim, Seok-Woo Seong, Si Wan Choi, Hyeon-Cheol Gwon, Seung-Ho Hur, Seung-Woon Rha, Chang-Hwan Yoon, Myung Ho Jeong, Jin-Ok Jeong
Summary: This study aimed to investigate whether the impact of diabetes mellitus on clinical outcomes after acute myocardial infarction (AMI) varies by age. The results showed that diabetes mellitus is more common in younger AMI patients, and the relative risk of 3-year mortality is significantly higher in young patients compared to older counterparts.
DIABETES & METABOLISM
(2022)
Article
Cardiac & Cardiovascular Systems
Viveca Ritsinger, Emil Hagstrom, Bo Lagerqvist, Anna Norhammar
Summary: Elevated glucose levels at admission in acute myocardial infarction patients without diabetes are associated with increased long-term risk of complications, particularly hospitalization for heart and renal failure. These findings highlight the potential usefulness of admission glucose levels in risk assessment following myocardial infarction.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Medicine, General & Internal
Ygal Plakht, Harel Gilutz, Arthur Shiyovich
Summary: This study evaluated the prognostic significance of HbA(1C) levels and changes among diabetic patients after non-fatal AMI. The results showed that fluctuations in HbA(1C) values, especially rapid increases, were associated with a higher risk of mortality. Monitoring both absolute HbA(1C) values and their changes could help predict long-term outcomes in AMI-DM patients.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Endocrinology & Metabolism
Han Feng, Hao Shen, Matthew J. Robeson, Yue-Han Wu, Hong-Kun Wu, Geng-Jia Chen, Shuo Zhang, Peng Xie, Li Jin, Yanyun He, Yingfan Wang, Fengxiang Lv, Xinli Hu, Yan Zhang, Rui-Ping Xiao
Summary: The E3 ligase-dead mutant MG53-C14A, a variant of the mitsugumin 53 (MG53) protein, not only protects the heart from acute myocardial injury but also counteracts metabolic stress, making it a potentially important treatment for acute myocardial injury in metabolic disorders, including diabetes and obesity.
Article
Clinical Neurology
Alice Chun-Chen Chen, Kuan-Lun Huang, Hong-Ming Chen, Pau-Chung Chen, Vincent Chin-Hung Chen, Wei-Che Chiu
Summary: The study revealed that in diabetic patients, those who used antidepressants for more than 180 days had a lower risk of myocardial infarction, especially when the duration of use exceeded 180 days.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Cardiac & Cardiovascular Systems
Nan Li, Jinying Zhou, Runzhen Chen, Xiaoxiao Zhao, Jiannan Li, Peng Zhou, Chen Liu, Yi Chen, Ying Wang, Li Song, Shaodi Yan, Hanjun Zhao, Hongbing Yan
Summary: This study aimed to investigate the impact of lipoprotein(a) [Lp(a)] levels on the prognosis of Chinese patients with ST-segment elevation myocardial infarction (STEMI), and to explore if the impact may differ in the diabetes mellitus (DM) and nonDM groups. The study found that high Lp(a) levels were associated with an increased risk of major adverse cardiovascular events (MACE), particularly in patients with DM. No similar association was found in the nonDM group.
CARDIOVASCULAR DIABETOLOGY
(2023)
Article
Endocrinology & Metabolism
Volker H. Schmitt, Lukas Hobohm, Thomas Munzel, Philip Wenzel, Tommaso Gori, Karsten Keller
Summary: This study found that diabetic patients have a higher in-hospital mortality rate and a higher recurrent MI rate during acute myocardial infarction (MI) compared to non-diabetic patients. Diabetic patients also had lower rates of coronary artery angiography and interventional revascularization compared to non-diabetic patients.
DIABETES & METABOLISM
(2021)
Article
Medicine, General & Internal
Yu Ri Kim, Myung Ho Jeong, Youngkeun Ahn, Ju Han Kim, Young Joon Hong, Min Chul Kim, Kyung Hoon Cho, Xiong Yi Han
Summary: This study compared long-term clinical outcomes between male and female acute myocardial infarction (AMI) patients with and without diabetes mellitus (DM). The results showed that in diabetic patients, outcomes did not significantly differ by sex, while in non-diabetic patients, mortality and major adverse cardiac events were higher in males than females.
KOREAN JOURNAL OF INTERNAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Anne M. Kerola, Anne Grete Semb, Markus Juonala, Antti Palomaki, Paivi Rautava, Ville Kyto
Summary: This study found that patients with type 1 diabetes have significantly poorer long-term cardiovascular prognosis after myocardial infarction compared to patients without diabetes, with a higher incidence of major adverse cardiovascular events. The results highlight the importance of effective secondary prevention after myocardial infarction in patients with type 1 diabetes.
CARDIOVASCULAR DIABETOLOGY
(2022)
Article
Endocrinology & Metabolism
Thien Vinh Luong, Mette Glavind Bulow Pedersen, Mette Louise Blouner Gram Kjaerulff, Simon Madsen, Katrine Meyer Lauritsen, Lars Poulsen Tolbod, Esben Sondergaard, Lars Christian Gormsen
Summary: The study on cardiac insulin resistance in patients with ischemic heart failure before cardiac viability testing did not find a direct impact of cardiac IR on mortality and major cardiovascular events.
METABOLISM-CLINICAL AND EXPERIMENTAL
(2021)
Article
Endocrinology & Metabolism
Tae-Jin Song, Jimin Jeon, Jinkwon Kim
Summary: This study highlighted the independent risk factors of periodontitis and poor oral hygiene for cerebral or myocardial infarction in the diabetes population. The findings suggested that early identification and intervention of periodontal disease, as well as improved oral hygiene practices, could potentially reduce cardiovascular complications in individuals with diabetes.
DIABETES & METABOLISM
(2021)
Article
Hematology
Jing-gang Xia, Bowen Li, Hao Zhang, Qin-xue Li, Sin Man Lam, Chun-lin Yin, He Tian, Guanghou Shui
Summary: This study used quantitative metabolomics to investigate the metabolic differences in acute myocardial infarction (AMI) patients with and without diabetes. The findings revealed that diabetes-AMI patients had more severe metabolic dysregulation, involving multiple pathways such as carbohydrate metabolism, lipid metabolism, glycolysis, tricarboxylic acid cycle, and amino acid metabolism. The key functional metabolites N-lactoyl-phenylalanine and lysophosphatidylcholines were identified, which were associated with mitochondrial dysfunction, glucose utilization, and inflammation, suggesting their potential as therapeutic targets for diabetes-AMI.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2023)
Article
Endocrinology & Metabolism
Ygal Plakht, Yuval Elkis Hirsch, Arthur Shiyovich, Muhammad Abu Tailakh, Idit F. Liberty, Harel Gilutz
Summary: The study revealed heterogeneity in the impact of T2DM on the long-term mortality of post-AMI patients, with a greater impact among young patients, especially females, and no significant impact in octogenarians.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)
Article
Cardiac & Cardiovascular Systems
Dae Young Cheon, Kyungdo Han, Ye Seul Yang, Yerim Kim, Sang-Hwa Lee, Chulho Kim, Jong-Hee Sohn, Mi Sun Oh, Byung-Chul Lee, Minwoo Lee, Kyung-Ho Yu
Summary: This study found a significant association between migraines and major cardiovascular events, including myocardial infarction, ischemic stroke, and cardiovascular death, in individuals with type 2 diabetes. The presence of aura symptoms in migraines further increased the risk of myocardial infarction.
CARDIOVASCULAR DIABETOLOGY
(2022)
