Characterization of Cytomegalovirus Breakthrough Events in a Phase 2 Prophylaxis Trial of Letermovir (AIC246, MK 8228)

Phenotypic characterization of two naturally occurring human Cytomegalovirus sequence polymorphisms located in a distinct region of ORF UL56 known to be involved in in vitro resistance to letermovir

(2015) Thomas Goldner et al.   ANTIVIRAL RESEARCH

Recent Advances in Cytomegalovirus: An Update on Pharmacologic and Cellular Therapies

(2015) Michael Boeckh et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Human cytomegalovirus (CMV) susceptibility to currently approved antiviral drugs does not impact on CMV terminase complex polymorphism

(2014) Léa Pilorgé et al.   ANTIVIRAL RESEARCH

Letermovir for Cytomegalovirus Prophylaxis in Hematopoietic-Cell Transplantation

(2014) Roy F. Chemaly et al.   NEW ENGLAND JOURNAL OF MEDICINE

Taming the Transplantation Troll by Targeting Terminase

(2014) Paul D. Griffiths et al.   NEW ENGLAND JOURNAL OF MEDICINE

CMV: Prevention, Diagnosis and Therapy

(2013) C. N. Kotton   AMERICAN JOURNAL OF TRANSPLANTATION

Geno- and Phenotypic Characterization of Human Cytomegalovirus Mutants SelectedIn Vitroafter Letermovir (AIC246) Exposure

(2013) Thomas Goldner et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Preemptive treatment of Cytomegalovirus infection in kidney transplant recipients with letermovir: results of a Phase 2a study

(2013) Susanne Stoelben et al.   TRANSPLANT INTERNATIONAL

Antiviral treatment of cytomegalovirus infection: an update

(2012) Georg Härter et al.   EXPERT OPINION ON PHARMACOTHERAPY

First Report of Successful Treatment of Multidrug-Resistant Cytomegalovirus Disease with the Novel Anti-CMV Compound AIC246

(2011) D. R. Kaul et al.   AMERICAN JOURNAL OF TRANSPLANTATION

In VitroEvaluation of the Activities of the Novel Anticytomegalovirus Compound AIC246 (Letermovir) against Herpesviruses and Other Human Pathogenic Viruses

(2011) Manfred Marschall et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The biology of cytomegalovirus drug resistance

(2011) Morgan Hakki et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Cytomegalovirus in Hematopoietic Stem Cell Transplant Recipients

(2011) Per Ljungman et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

The Novel Anticytomegalovirus Compound AIC246 (Letermovir) Inhibits Human Cytomegalovirus Replication through a Specific Antiviral Mechanism That Involves the Viral Terminase

(2011) T. Goldner et al.   JOURNAL OF VIROLOGY

In Vitro and In Vivo Activities of the Novel Anticytomegalovirus Compound AIC246

(2010) P. Lischka et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antiviral Drug Resistance of Human Cytomegalovirus

(2010) N. S. Lurain et al.   CLINICAL MICROBIOLOGY REVIEWS

A new tool linking human cytomegalovirus drug resistance mutations to resistance phenotypes

(2009) Meike Chevillotte et al.   ANTIVIRAL RESEARCH

Antiviral strategies to combat cytomegalovirus infections in transplant recipients

(2008) P LISCHKA et al.   CURRENT OPINION IN PHARMACOLOGY