Biosynthetic Mechanism of Lanosterol: Cyclization

Concerted Cyclization of Lanosterol C-Ring and D-Ring Under Human Oxidosqualene Cyclase Catalysis: An ab Initio QM/MM MD Study

(2014) Nanhao Chen et al.   Journal of Chemical Theory and Computation

The Concerted Nature of the Cyclization of Squalene Oxide to the Protosterol Cation

(2013) B. Andes Hess et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aminopropylindenes derived from Grundmann's ketone as a novel chemotype of oxidosqualene cyclase inhibitors

(2013) Stefanie Lange et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Protein engineering of oxidosqualene-lanosterol cyclase into triterpene monocyclase

(2013) Cheng-Hsiang Chang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Combined ligand and structure based binding mode analysis of oxidosqualene cyclase inhibitors

(2013) N. S. Hari Narayana Moorthy et al.   RSC Advances

Cytotoxic Effects of Combination of Oxidosqualene Cyclase Inhibitors with Atorvastatin in Human Cancer Cells

(2012) Davide Staedler et al.   JOURNAL OF MEDICINAL CHEMISTRY

Catalytic Mechanism and Product Specificity of Oxidosqualene-Lanosterol Cyclase: A QM/MM Study

(2012) Bo-Xue Tian et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Biosynthesis of Cholesterol and Other Sterols

(2011) W. David Nes   CHEMICAL REVIEWS

Biosynthesis via carbocations: Theoretical studies on terpene formation

(2011) Dean J. Tantillo   NATURAL PRODUCT REPORTS

Differential Stereocontrolled Formation of Tricyclic Triterpenes by Mutation of Tyrosine 99 of the Oxidosqualene-Lanosterol Cyclase fromSaccharomyces cerevisiae

(2009) Tung-Kung Wu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Saccharomyces cerevisiaeoxidosqualene-lanosterol cyclase: A chemistry-biology interdisciplinary study of the protein's structure-function-reaction mechanism relationships

(2008) Tung-Kung Wu et al.   CHEMICAL RECORD

Importance ofSaccharomyces cerevisiaeOxidosqualene-Lanosterol Cyclase Tyrosine 707 Residue for Chair-Boat Bicyclic Ring Formation and Deprotonation Reactions

(2008) Tung-Kung Wu et al.   ORGANIC LETTERS