Article
Nutrition & Dietetics
Andrew W. McHill, Joseph T. Hull, Elizabeth B. Klerman
Summary: Chronic circadian disruption and insufficient sleep are independently associated with poor health outcomes. This study found that chronic circadian disruption was associated with decreased hunger and appetite, and these changes were correlated with changes in the ghrelin/leptin ratio.
Article
Agriculture, Dairy & Animal Science
L. M. Soranno, A. K. Jones, S. M. Pillai, M. L. Hoffman, S. A. Zinn, K. E. Govoni, S. A. Reed
Summary: The study found that poor maternal nutrition during gestation can negatively affect offspring growth and development. Leptin and ghrelin may play important roles as mediators in this process. Maternal diet can alter plasma concentrations of leptin and ghrelin in ewes and offspring, as well as the concentrations of these hormones at different stages of gestation.
DOMESTIC ANIMAL ENDOCRINOLOGY
(2022)
Article
Medicine, General & Internal
Piotr Pardak, Rafal Filip, Jaroslaw Wolinski, Maciej Krzaczek
Summary: The study found that gastroesophageal reflux disease (GERD) is more common in patients with obstructive sleep apnea (OSA). Lower ghrelin levels were observed in severe OSA patients, with correlations to severity of esophagitis and GERD symptoms, while leptin levels were correlated with lower esophageal pH. The relationship between OSA and GERD does not result from hormonal disorders, as no significant differences in hormonal levels were found based on GERD diagnosis.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Nutrition & Dietetics
Svenja Meyhoefer, Rodrigo Chamorro, Manfred Hallschmid, Denisa Spyra, Nelli Klinsmann, Bernd Schultes, Hendrik Lehnert, Sebastian M. Meyhoefer, Britta Wilms
Summary: Evidence shows that reduced sleep duration can increase hunger, appetite, and food intake, leading to metabolic diseases like type 2 diabetes and obesity. However, the impact of sleep timing on hunger and appetite regulation is less clear independent of sleep duration. This study aimed to evaluate the effect of sleep loss during late night vs. early night on hunger, appetite, and desire for food. The results indicate that sleep loss during late night, but not early night, increases ghrelin levels and feelings of hunger and appetite, highlighting the metabolic relevance of chronobiological sleep timing.
Article
Medicine, General & Internal
Piotr Pardak, Rafal Filip, Jaroslaw Wolinski
Summary: This study found an association between obesity and sleep-related breathing disorders. Both disorders affect ghrelin levels, with obesity parameters negatively correlated with hormone concentration. OSA appears to lower ghrelin values in the second half of the night.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Bradley E. Aouizerat, Eeeseung Byun, Clive R. Pullinger, Caryl Gay, Anners Lerdal, Kathryn A. Lee
Summary: The study found associations between selected genes and plasma markers related to energy homeostasis and sleep disruption in adults with HIV/AIDS. Many of these associations were influenced by HIV disease markers. Higher levels of adiponectin were associated with less wake after sleep onset, while higher levels of ghrelin and glucose were associated with shorter total sleep time, and higher levels of leptin were associated with longer total sleep time.
Article
Nutrition & Dietetics
Hassan S. Dashti, Puri Gomez-Abellan, Jingyi Qian, Alberto Esteban, Eva Morales, Frank A. J. L. Scheer, Marta Garaulet
Summary: The study found that individuals who ate dinner late had higher BMI and triglyceride concentrations at baseline, as well as lower insulin sensitivity. Additionally, those who ate dinner late had a slower rate of weight loss and were more likely to encounter barriers to weight loss.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Medicine, General & Internal
Justyna Kuliczkowska-Plaksej, Aleksandra Jawiarczyk-Przybylowska, Agnieszka Zembska, Katarzyna Kolackov, Joanna Syrycka, Marcin Kaluzny, Beata Polowczyk-Kawalko, Eliza Kubicka, Marek Bolanowski
Summary: SARS-CoV2 infection can cause severe cytokine storm, especially in obese patients. Ghrelin and leptin concentrations were assessed in COVID-19 patients 6 months after infection compared to a control group, with consideration of sex differences. Ghrelin levels were significantly higher in COVID-19 patients, while no differences were found in leptin levels.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Biochemistry & Molecular Biology
Vania Miloucheva Peneva, Dora Dimitrova Terzieva, Mitko Dimitrov Mitkov
Summary: Metabolic syndrome (MetS) is a combination of cardiometabolic risk factors that increase the chances of developing type 2 diabetes, cardiovascular diseases, and death. In women, an insulin-resistant state associated with polycystic ovarian syndrome and increased intra-abdominal fat deposition promotes the development of MetS and increases cardiovascular risk. The hormone melatonin, which is regulated by the suprachiasmatic nucleus, plays a role in this process. The relationship between melatonin and the main features of MetS in women, including glucose metabolism, lipid disturbances, hypertension, and vascular dysfunction, is discussed in this review.
Article
Nutrition & Dietetics
Alessandro Micarelli, Alessandra Vezzoli, Sandro Malacrida, Beatrice Micarelli, Ilaria Misici, Valentina Carbini, Ilaria Iennaco, Sara Caputo, Simona Mrakic-Sposta, Marco Alessandrini
Summary: This study aimed to evaluate the differences in gustatory sensitivity, nutritional habits, circulating levels of modulators, anthropometric measures, and metabolic assays between overweight and obesity participants and lean subjects. The results showed significant reductions in taste scores and changes in biochemical factors and nutritional habits as obesity progressed.
Article
Nutrition & Dietetics
Martina Platzer, Frederike T. Fellendorf, Susanne A. Bengesser, Armin Birner, Nina Dalkner, Carlo Hamm, Melanie Lenger, Alexander Maget, Rene Pilz, Robert Queissner, Bernd Reininghaus, Alexandra Reiter, Harald Mangge, Sieglinde Zelzer, Hans-Peter Kapfhammer, Eva Z. Reininghaus
Summary: This study explores the underlying causes of obesity and weight gain in bipolar disorder, as well as the associations between food craving, clinical parameters, psychotropic medication, and appetite-related hormones. Results show that individuals with bipolar disorder have higher food craving frequencies compared to healthy controls, with a significant negative correlation between food craving and ghrelin levels. Smoking status and age are significantly associated with food craving intensity, and different medication therapies also influence food craving levels.
Article
Biochemistry & Molecular Biology
Junewoo Na, Byong Seo Park, Doohyeong Jang, Donggue Kim, Thai Hien Tu, Youngjae Ryu, Chang Man Ha, Marco Koch, Sungchil Yang, Jae Geun Kim, Sunggu Yang
Summary: This study extensively characterizes the AgRP, POMC, and dopaminergic neurons in the hypothalamic arcuate nucleus (Arc). The distinct anatomical and physiological properties of these neurons in response to appetite-regulating hormones are identified. This research highlights the importance of hypothalamic Arc neurons in appetite control.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Clinical Neurology
Shannon S. Sullivan, Michelle T. Cao
Summary: Based on the survey results, there is wide variability and overall low exposure to sleep medicine education among parent Accreditation Council of Graduate Medical Education training programs in the United States.
JOURNAL OF CLINICAL SLEEP MEDICINE
(2021)
Article
Health Care Sciences & Services
Jeffrey D. Krimmel-Morrison, Gurpreet Dhaliwal
Summary: Lifelong learning is crucial in the medical field, but many residents lack the skills to be effective self-directed learners. This article presents a practical training plan to help residents improve their clinical knowledge and reasoning, and offers tips for implementation and refinement.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Article
Clinical Neurology
Gulay Tasci, Suheda Kaya, Mehmet Kalayci, Murad Atmaca
Summary: This study compared the levels of acyl ghrelin (AG), des-acyl ghrelin (DAG), and leptin in patients with antisocial personality disorder (ASPD) and healthy controls. The results showed that AG and DAG levels were significantly higher in patients, while leptin levels were significantly lower. There was also a positive correlation between AG and DAG levels and impulsivity and aggression.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Environmental Sciences
Ricardo Cardoso Cassilhas, Ricardo Augusto Leoni De Sousa, Luciana Caxa, Valter Viana, Romain Meeusen, Fabio Luiz Goncalves, Caique Olegario Magalhaes, Sergio Tufik, Marco Fabricio Dias Peixoto, Renato Sobral Monteiro Junior, Marco Tulio de Mello
Summary: Indoor aerobic exercise, compared to outdoor exercise, results in lower pollution exposure for elderly individuals, leading to improved cognitive function and increased BDNF levels. Additionally, indoor exercise shows significant benefits for glycemic control.
AIR QUALITY ATMOSPHERE AND HEALTH
(2022)
Article
Biology
Lucas Alves Facundo, Valdenio Martins Brant, Renato Carvalho Guerreiro, Henrique de Araujo Andrade, Fernando Mazzilli Louzada, Andressa Silva, Marco Tulio de Mello
Summary: This study aims to describe the sleep regularity of athletes using the Sleep Regularity Index (SRI) and investigate the effects of factors such as sex, competitive level, and sport type on their sleep/wake rhythm. The findings reveal that international level athletes, female athletes, and individual sport athletes have better sleep regularity.
CHRONOBIOLOGY INTERNATIONAL
(2022)
Article
Rehabilitation
Andressa Silva, Larissa Santos Pinto Pinheiro, Samuel Silva, Henrique Andrade, Andre Gustavo Pereira, Flavia Rodrigues da Silva, Renato Guerreiro, Bruna Barreto, Renan Resende, Marco Tulio de Mello
Summary: Paralympic athletes tend to have poor sleep quality, exhibit poor sleep behavior, and sleep less than recommended. Insomnia symptoms, frequency of awakenings at night, movements during sleep, and poor sleep quality are associated with the occurrence and/or severity of health problems.
PHYSICAL THERAPY IN SPORT
(2022)
Article
Nutrition & Dietetics
Sandra Maria Chemin Seabra da Silva, Aline de Piano Ganen, Deborah Cristina Landi Masquio, Marcus V. L. Dos Santos Quaresma, Debora Estadella, Lila Missae Oyama, Lian Tock, Marco Tulio de Mello, Ana Raimunda Damaso, Claudia Maria da Penha Oller do Nascimento, Danielle Arisa Caranti
Summary: This study aimed to verify the relationships between serum-free fatty acids (FA), inflammatory processes, and depressive symptoms in obese adolescents. The results showed positive correlations between depressive symptoms and saturated fatty acids (SFA) content, body fat, and inflammatory adipokines. On the other hand, n-3 polyunsaturated fatty acids (PUFA) content was negatively correlated with depressive symptoms. However, further longitudinal studies are needed to confirm the causality between dietary SFA and depression in obese individuals.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Physiology
Adriano A. L. Carmo, Karine N. O. Goulart, Christian E. T. Cabido, Ygor A. T. Martins, Gabriela C. F. Santos, Felipe L. T. Shang, Luciano S. Prado, Danusa D. Soares, Marco T. de Mello, Thiago T. Mendes, Emerson Silami-Garcia, Samuel P. Wanner
Summary: This study investigated the effects of an active warm-up and time-of-day variation on repeated-sprint performance and post-exercise recovery. The results showed that a warm-up improved sprint performance, and sprints performed in the late afternoon were better. Additionally, warm-up also led to faster post-exercise recovery.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Nutrition & Dietetics
Luciana Fidalgo Ramos Nogueira, Cibele Aparecida Crispim, Jose Cipolla-Neto, Claudia Roberta de Castro Moreno, Elaine Cristina Marqueze
Summary: This study aimed to evaluate the effects of exogenous melatonin administration on eating habits in female night workers with excessive weight. The results showed that melatonin treatment did not significantly affect the quality, quantity, and timing of food intake. In addition, circadian misalignment and chronotype were not associated with these outcomes.
Article
Nutrition & Dietetics
Bruno Simao Teixeira, Catarina Mendes Silva, Alinne Tatiane Faria Silva, Leticia Lopes Dantas Santos, Yara Cristina de Paiva Maia, Mario Pedrazzoli, Kenneth P. P. Wright Jr, Cibele Aparecida Crispim
Summary: Fasting during the night shift leads to increased intake of energy and macronutrients both in the early morning after work and throughout the next day, as well as lower insulin levels and HOMA-IR in the morning.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Article
Rehabilitation
Isadora Grade, Henrique Andrade, Renato Guerreiro, Eduardo Stieler, Flavia R. da Silva, Hesojy G. V. da Silva, Roberto Vital, Renan A. Resende, Dawit A. P. Goncalves, Andre G. Andrade, Marco T. de Mello, Andressa Silva
Summary: A systematic review found that Paralympic athletes have poor sleep quality and quantity, with high rates of daytime sleepiness. Subjective questionnaires are commonly used to assess their sleep.
JOURNAL OF SPORT REHABILITATION
(2023)
Article
Physiology
Marlene Salvina Fernandes da Costa, Vinicius de Oliveira Damasceno, Marco Tulio de Melo, Marcos Andre Moura dos Santos, Wlaldemir Roberto dos Santos, Fernanda Veruska Narciso, Walmir Romario dos Santos, Saulo Fernandes Melo de Oliveira, Pedro Pinheiro Paes
Summary: This study aims to investigate the direct influence of training load on sleep behavior during the tapering phase of training for young swimmers. The results show that there is no significant influence of training load on sleep variables. However, a strong association between total sleep time (TST) and external load (EL) was observed in the irregular sleep group.
REVISTA BRASILEIRA DE MEDICINA DO ESPORTE
(2023)
Article
Nutrition & Dietetics
Luisa Pereira Marot, Laura Cristina Tibiletti Balieiro, Tassia do Vale Cardoso Lopes, Dayane Eusenia Rosa, Kenneth P. P. Wright Jr, Claudia Roberta de Castro Moreno, Cibele Aparecida Crispim
Summary: The purpose of this study was to evaluate the variability of meal timing in rotating shift workers throughout a complete shift schedule and its effect on daily energy and macronutrient intake. The results showed that night shifts contribute to a longer eating window and higher energy and macronutrient intake compared to other shifts. This may reduce the fasting period during the night and have implications for metabolic dysregulation.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Review
Nutrition & Dietetics
Luisa Pereira Marot, Tassia do Vale Cardoso Lopes, Laura Cristina Tibiletti Balieiro, Cibele Aparecida Crispim, Claudia Roberta Castro Moreno
Summary: This review discusses the impact of eating behavior on the reduction of overnight fasting in shift workers and possible nutritional strategies involving fasting. Although the approach seems to be feasible and beneficial for shift workers, more research is needed to explore the potential risks and benefits and establish specific guidelines.
Review
Rehabilitation
Eduardo Stieler, Marco T. de Mello, Ingrid L. B. Lobo, Dawit A. Goncalves, Renan Resende, Andre G. Andrade, Thiago F. Lourenco, Anselmo A. C. Silva, Henrique A. Andrade, Renato Guerreiro, Andressa Silva
Summary: This review examines the methods used to assess external load in Paralympic sports, aiming to provide scientific evidence for multidisciplinary teams to prescribe and monitor athlete's development, enhance performance, and reduce injury/illness risks. The study identified 8 methods to quantify external load in 8 different Paralympic sports and highlights the need for further research to validate the effectiveness and reliability of these methods.
JOURNAL OF SPORT REHABILITATION
(2023)
Article
Nutrition & Dietetics
Ronaldo Angelo Dias da Silva, Leszek Antoni Szmuchrowski, Joao Paulo Pereira Rosa, Marcos Antonio Pereira dos Santos, Marco Tulio de Mello, Lucas Savoi, Yves Ferreira Porto, Francisco de Assis Dias Martins, Marcos Daniel Motta Drummond
Summary: Intermittent fasting (IF) is commonly used by combat sports athletes for weight loss but may decrease performance. This study examined the effects of IF on body weight and Taekwondo performance. The results showed that IF led to a decrease in body weight in the first two weeks but stabilized afterwards. Performance in vertical jumping had different patterns in fed and fasted states. Despite the decrease in body weight, IF did not significantly impact performance.
Review
Nutrition & Dietetics
Renata Soares de Almeida, Luisa Pereira Marot, Carolina de Oliveira Cruz Latorraca, Ricardo de avila Oliveira, Cibele Aparecida Crispim
Summary: This systematic review summarized randomized clinical trials comparing the postprandial glycemic and insulinemic response after eating carbohydrate meals in the morning versus at night. The results showed higher glycemic values in the evening compared to the morning, but no significant difference in insulin values.
JOURNAL OF THE AMERICAN NUTRITION ASSOCIATION
(2023)
Review
Sport Sciences
Aldo C. Silva, Adriana S. Amaral, Renato Guerreiro, Andressa Silva, Marco T. deMello, Sergio G. daSilva, Leandro Rechenchosky, Wilson Rinaldi
Summary: Sleep patterns and associated factors among elite soccer athletes were examined in this study. The findings indicate that elite soccer athletes often fail to meet the recommended sleep guidelines, which can be influenced by match outcomes and travel.
APUNTS SPORTS MEDICINE
(2022)