期刊
CHROMOSOME RESEARCH
卷 19, 期 3, 页码 307-319出版社
SPRINGER
DOI: 10.1007/s10577-011-9198-3
关键词
chromosome structure; condensation; condensin; topoisomerase II; cohesin
资金
- BBSRC [BB/H013024, BB/G01518X]
- Biotechnology and Biological Sciences Research Council [BB/H013024/1] Funding Source: researchfish
- BBSRC [BB/H013024/1] Funding Source: UKRI
Proper mitotic chromosome structure is essential for faithful chromosome segregation. Mounting evidence suggests that mitotic chromosome assembly is a progressive, dynamic process that requires topoisomerase II, condensins and cohesin and the activity of several signalling molecules. Current results suggest how these different activities might interact to achieve the familiar form of the mitotic chromosome.
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