Article
Agriculture, Multidisciplinary
Michaela Maleckova, Tomas Vrzal, Jana Olsovska, Jana Sobotnikova
Summary: This study focuses on the identification and structural characterization of nitrite reaction products in beer, discovering 19 representatives of nitroso, nitro, oxime, and even cyano compounds. The presence of these compounds in non-treated beers was confirmed through screening in 16 authentic beer samples.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Review
Food Science & Technology
Huynh N. P. Dang, Joselito P. Quirino
Summary: Alkenylbenzenes are potentially toxic compounds found in food, especially in flavorings, requiring constant monitoring due to concerns about their health effects. The challenge in determining alkenylbenzenes in food lies in the complex sample matrices and low amounts present. Gas and liquid chromatography are commonly used separation techniques, with detection methods including flame ionisation and mass spectrometry.
Review
Chemistry, Analytical
Sanka N. Atapattu, Azamat Temerdashev
Summary: Gas chromatography is a widely used analytical technique, but not all analytes can be directly analyzed. Analytical derivatization, such as injector port derivatization, is often required to improve the suitability of analytes for gas chromatographic analysis. This technique is easy to use, efficient, and requires fewer hazardous chemicals.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Samin Fathalinejad, Esben Taarning, Peter Christensen, Jan H. Christensen
Summary: This study developed a GC-MS identification workflow for carbohydrate fragmentation compounds, built a library of compounds detected by five different GC-MS methods, investigated and compared compound coverage among the methods, and explored possible reaction pathways for some analytes. A total of 389 compounds were detected, with solid-phase microextraction detecting the highest number of analytes and derivatization GC-MS technique detecting the lowest but largest molecules.
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
(2021)
Article
Chemistry, Multidisciplinary
Dan Zhang, Sifan Wang, Fangxi Yang, Qingrong Qi, Yanfang Li, Wencai Huang
Summary: The responses of the reaction-based fluorescent probe BI-Py towards various chemical compounds were evaluated, and it selectively detected ethyl triflate in acetonitrile with a LOD of 1.08 μM. BI-Py showed great potential for the detection of triflate as a genotoxic impurity in drug substances.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Naeem Khan, Nargis Jamila, Farhat Amin, Rehana Masood, Amir Atlas, Wajheeba Khan, Noor Ul Ain, Sadiq Noor Khan
Summary: This study investigated the elemental content and antimicrobial activities of thirteen medicinal herbs in the local markets of Pakistan. The herbs were found to contain high levels of essential elements and low levels of toxic elements, with significant antimicrobial potential against various pathogens.
ARABIAN JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Analytical
Merel J. Lefferts, Lisa H. Humphreys, Nathalie Mai, Krishnan Murugappan, Ben Armitage, Jean-Francois Pons, Martin R. Castell
Summary: The development of ANFO vapour sensors for widespread IED detection faces challenges in achieving high sensitivity and low detection limits due to concealment and low vapour pressures. By using polymer percolation networks, ANFO chemiresistive vapour sensors show improved sensitivity compared to thin film sensors, detecting vapour concentrations emitted by various ammonium nitrate-containing fertilisers and fertiliser-diesel mixtures.
Article
Food Science & Technology
B. B. Carlos Filho, Junior M. M. Furlan, Cristiano R. R. de Menezes, Alexandre J. J. Cichoski, Roger Wagner, Paulo C. B. Campagnol, Jose M. Lorenzo
Summary: In recent decades, meat consumption worldwide has increased from 30 kg/person/year in the 1980s to 43.4 kg in 2015. Analyzing the fatty acid (FA) composition in meat products is important due to its influence on chemical and sensory characteristics, as well as nutritional quality. This review discusses the methodologies used for sample preparation for FA analysis in raw meat products using gas chromatography equipped with a flame ionization detector (GC-FID). The review highlights the different steps involved in sample preparation and emphasizes the need for faster, cost-effective, and environmentally friendly methods.
FOOD ANALYTICAL METHODS
(2023)
Article
Chemistry, Analytical
Brittany Widner, Melissa C. Kido Soule, Frank Xavier Ferrer-Gonzalez, Mary Ann Moran, Elizabeth B. Kujawinski
Summary: Utilizing pre-extraction derivatization and ultrahigh performance liquid chromatography electrospray ionization tandem mass spectrometry, targeted dissolved metabolites in seawater and saline culture media were successfully detected and quantified. This quantitative method has been optimized for 73 common metabolites, with 50 requiring derivatization for quantification due to low extraction efficiencies.
ANALYTICAL CHEMISTRY
(2021)
Review
Pharmacology & Pharmacy
Siu Kan Law, Yanping Wang, Xinchen Lu, Dawn Ching Tung Au, Wesley Yeuk Lung Chow, Albert Wing Nang Leung, Chuanshan Xu
Summary: Obesity is a global health threat and traditional Chinese medicine offers a potential solution, but there are still challenges that need to be addressed. Prodrugs could help overcome the deficiencies and provide insights for designing effective treatments for obesity.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Environmental Sciences
Kwabena F. M. Opuni, Samuel Asare-Nkansah, Paul Osei-Fosu, Abraham Akonnor, Samuel O. Bekoe, Alexander N. O. Dodoo
Summary: The study in Ghana investigated pesticide residues in herbal medicinal products and found levels below maximum residue limits, posing minimal health risks to patients. Regular monitoring and regulation of pesticide residue levels are recommended to reduce potential public health risks.
ENVIRONMENTAL MONITORING AND ASSESSMENT
(2021)
Article
Chemistry, Analytical
Rihab Fkiri, Ramzi Timoumi, Guillaume Rioland, Pauline Poinot, Fabien Baron, Brian Gregoire, Claude Geffroy-Rodier
Summary: In this study, a strategy adapted to space experimentation was developed to detect amino acid-like compounds using GC-MS. The optimized derivatization methods meet the design constraints of extraterrestrial experiments. The combination of fast selective extraction and GC analysis enables efficient detection of organic materials. In the future, the corresponding GC-MS TIC could be used for simple and fast selection of sediments/dust samples onboard rovers equipped with GC-MS for sample return-to-Earth missions.
Review
Chemistry, Analytical
Apostolia Tsiasioti, Constantinos K. Zacharis, Paraskevas D. Tzanavaras
Summary: This article reviews recent studies on the determination of histamine in food matrices using derivatization-based separation methods. The derivatization of histamine plays an important role in enhancing sensitivity, selectivity, and compatibility to analytical techniques. The article also discusses the application of the latest derivatizing reagents for histamine and various analytical techniques.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Review
Biochemistry & Molecular Biology
Surya Nath Pandey, Naresh Kumar Rangra, Sima Singh, Saahil Arora, Varun Gupta
Summary: Alzheimer's disease is a prevalent neurodegenerative disease that causes dementia, with limited clinical treatment effectiveness due to unknown origin and blood-brain barrier restrictions. Plants offer potential avenues for new drug discovery, but further research is needed to validate their efficacy in alternative therapies.
ACS CHEMICAL NEUROSCIENCE
(2021)
Article
Food Science & Technology
Shu-Han Zhang, Yun Wang, Jing Yang, Dan-Dan Zhang, Yan-Lei Wang, Shu-Hui Li, Ying-Ni Pan, Hua-Min Zhang, Yi Sun
Summary: This study analyzed the composition and content of aristolochic acids (AAs) in three medicinal herbs of the Aristolochia genus and evaluated their cytotoxicity and genotoxicity. The results showed the presence of multiple AAs with high cytotoxicity and genotoxicity in these herbs.
