Article
Food Science & Technology
Iris Fiby, Marta Magdalena Sopel, Herbert Michlmayr, Gerhard Adam, Franz Berthiller
Summary: A new LC-MS/MS method for determining Fusarium mycotoxin in maize was developed and validated, with the use of stable-isotope dilution technique in a complex cereal matrix. The method successfully quantified the toxins and efficiently corrected matrix effects in the validation study.
Article
Food Science & Technology
Thammaporn Junsai, Saranya Poapolathep, Samak Sutjarit, Mario Giorgi, Zhaowei Zhang, Antonio Francesco Logrieco, Peiwu Li, Amnart Poapolathep
Summary: This study investigated the occurrence of multi-mycotoxins in six types of vegetable oils available in Thailand, revealing variations in mycotoxin contamination among different oil samples. The levels of analyzed mycotoxins were found to be below regulatory limits, indicating a low health risk to consumers.
Article
Food Science & Technology
Milena Stranska, Zbynek Dzuman, Nela Prusova, Adam Behner, Irena Kolouchova, Petra Lovecka, Tomas Rezanka, Miroslav Kolarik, Jana Hajslova
Summary: Fungal endophytes in grapevine have the potential to produce various mycotoxins, with verruculogen and gliotoxin being the most common and concentrated. It is important to carefully check the toxinogenic potential of endophytes when cultivating grapevines.
Article
Chemistry, Applied
Philipp Eyring, Marc Tienstra, Hans Mol, Susan Strange Herrmann, Peter Have Rasmussen, Henrik Lauritz Frandsen, Mette Erecius Poulsen
Summary: Various generic extraction methods have been used for determination of pesticide residues, mycotoxins, and PAHs in food and animal feed, but a new method introduced in this study facilitated identification of a wide range of compounds across different polarities. The method involved initial extraction with water, acetonitrile, formic acid, and heptane followed by solid-phase extraction clean-up and analysis by chromatography and mass spectrometry, achieving analyte recoveries with high accuracy and precision.
Review
Chemistry, Analytical
A. Fernez Asensio, E. Alvarez-Gonzalez, A. Rodriguez, L. M. Sierra, E. Blanco-Gonzalez
Summary: Dysregulation of TCA cycle enzymes leads to abnormal accumulation of oncometabolites, which contribute to cancer formation and progression. GC-MS and LC-MS are powerful analytical tools for accurate identification and determination of these metabolites.
ANALYTICA CHIMICA ACTA
(2021)
Article
Food Science & Technology
Mark M. Skinner, Jared T. Seale, Maranda S. Cantrell, Joseph M. Collins, Matthew W. Turner, Owen M. McDougal
Summary: This experimental study aimed to detect acrylamide in French fries using methods suitable for the food processing industry, comparing the pros and cons of each method to provide decision-making suggestions for food processors.
Article
Chemistry, Multidisciplinary
Julius Albert, Camilla A. More, Niklaus R. P. Dahlke, Zacharias Steinmetz, Gabriele E. Schaumann, Katherine Munoz
Summary: A simple and reliable method for quantitative analysis of Aflatoxins (AFs) in soil and food matrices at environmentally relevant concentrations was presented, demonstrating effectiveness even at trace levels and meeting the quality criteria set by the European Commission for mycotoxins. The method is sensitive, with quantification limits ranging from 0.04 to 0.23 μg/kg for HPLC-FLD and 0.06-0.23 μg/kg for LC-MS, and provides satisfactory recoveries and repeatability values within acceptable limits. Despite both instruments being capable of reliable analysis, the HPLC-FLD method may be more suitable for routine analysis due to its lack of matrix considerations.
Review
Medical Laboratory Technology
Kenichi Tamama
Summary: Drugs of abuse testing is commonly used in clinical and forensic settings, with urine being the preferred specimen type but other emerging types include saliva, sweat, hair, and meconium. Liquid chromatography-tandem mass spectrometry (LC-tandem-MS) has become the new gold standard for confirmatory drug testing due to its ability to analyze a wider range of analytes compared to gas chromatography-mass spectrometry (GC-MS). Technical advancements such as high-resolution mass spectrometry and miniature ambient ionization mass spectrometry have improved the speed and efficiency of drugs of abuse testing.
CLINICA CHIMICA ACTA
(2021)
Article
Chemistry, Applied
Petar Ristivojevic, Vesna Jovanovic, Dusanka Milojkovic Opsenica, Jihae Park, Judith M. Rollinger, Tanja Cirkovic Velickovic
Summary: A novel high-throughput methodological approach was developed for tracing compounds with radical scavenging and antimicrobial activities in brown seaweeds. Major components identified with these activities include stearidonic, eicosapentaenoic, and arachidonic acids. This method allows fast identification and quantification of bioactive compounds in multicomponent biological samples.
Review
Chemistry, Analytical
Deniss Fedorenko, Vadims Bartkevics
Summary: This article reviews the applications of nano-LC separation methods coupled with mass spectrometry in the analysis of food and environmental samples. It provides an assessment of sample preparation methods, analytical performance, and comparison to other analytical techniques. The article discusses recent practical applications of nano-LC methods in determining crucial compounds for food safety assessment and various environmental contaminants. Future perspectives for the development of nano-LC methods are also discussed.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2023)
Article
Polymer Science
Andrea Schweighuber, Alexander Felgel-Farnholz, Thomas Boegl, Joerg Fischer, Wolfgang Buchberger
Summary: The importance of mechanical recycling of polymers has increased in recent decades due to government regulations worldwide. The increased thermo-mechanical stress during the recycling process can significantly impact the quality of recyclates. Research has shown the occurrence of odd-numbered linear alkane chains in polyethylene samples and oxidized branched alkanes in polypropylene samples during the recycling process.
POLYMER DEGRADATION AND STABILITY
(2021)
Article
Food Science & Technology
Xin Guan, Yuchao Feng, Decheng Suo, Zhiming Xiao, Shi Wang, Ying Liang, Xia Fan
Summary: In this study, a method for detecting 11 mycotoxins in maize was established using multiple-impurity adsorption purification (MIA) technologies and liquid chromatography-tandem mass spectrometry (LC-MS/MS). The validated method was suitable for simultaneous determination of multiple mycotoxins in maize.
Article
Chemistry, Analytical
Yue Sun, Yu Liang, Chao Wang, Baofeng Zhao, Zhen Liang, Xiaodan Zhang, Yukui Zhang, Lihua Zhang
Summary: Comprehensive characterization of membrane proteins at the level of proteoforms in complex biological samples by top-down mass spectrometry (MS) is of vital importance in revealing their precise functions. However, severe peak broadening in the separation of hydrophobic membrane proteins, caused by resistance to mass transfer and strong adsorption on separation materials, leads to MS spectra overlap and signal suppression, which makes against the in-depth research on membrane proteoforms.
ANALYTICAL CHEMISTRY
(2023)
Article
Biochemical Research Methods
Jennifer Bates, Adilah Bahadoor, Sheryl A. Tittlemier, Jeremy E. Melanson
Summary: Analysis of low-level organic contaminants in complex matrices is important for global food safety monitoring. Balancing sample throughput with complex experimental designs and sample clean-up to reduce matrix effects is challenging. Multiple strategies exist to mitigate these effects, with internal standard-based methods such as isotope dilution mass spectrometry (IDMS) being the most advantageous.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Endocrinology & Metabolism
Jun Kou, Chunyang He, Lin Cui, Zhengping Zhang, Wei Wang, Li Tan, Da Liu, Wei Zheng, Wei Gu, Ning Xia
Summary: The study on Chinese postmenopausal women with osteoporosis identified potential biomarkers related to metabolic pathway disorders, providing new insights for early diagnosis. The findings suggest that metabonomic analysis has great potential for application in postmenopausal women with osteoporosis.
FRONTIERS IN ENDOCRINOLOGY
(2022)