A Jekyll and Hyde Profile: Type 1 Interferon Signaling Plays a Prominent Role in the Initiation and Maintenance of a Persistent Virus Infection

Of men, not mice

(2013)   NATURE MEDICINE

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blockade of Chronic Type I Interferon Signaling to Control Persistent LCMV Infection

(2013) E. B. Wilson et al.   SCIENCE

Persistent LCMV Infection Is Controlled by Blockade of Type I Interferon Signaling

(2013) J. R. Teijaro et al.   SCIENCE

Pathogenesis of Lassa fever virus infection: I. Susceptibility of mice to recombinant Lassa Gp/LCMV chimeric virus

(2013) Andrew M. Lee et al.   VIROLOGY

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

(2012) Ken T. Coppieters et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-10-Producing Regulatory B Cells in the Pathogenesis of Chronic Hepatitis B Virus Infection

(2012) A. Das et al.   JOURNAL OF IMMUNOLOGY

Infected CD8 - dendritic cells are the predominant source of IL-10 during establishment of persistent viral infection

(2012) C. T. Ng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intravital imaging of CTLs killing islet cells in diabetic mice

(2011) Ken Coppieters et al.   JOURNAL OF CLINICAL INVESTIGATION

T cell exhaustion

(2011) E John Wherry   NATURE IMMUNOLOGY

Point mutation in the glycoprotein of lymphocytic choriomeningitis virus is necessary for receptor binding, dendritic cell infection, and long-term persistence

(2011) B. M. Sullivan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-10 induces aberrant deletion of dendritic cells by natural killer cells in the context of HIV infection

(2010) Galit Alter et al.   JOURNAL OF CLINICAL INVESTIGATION

Early IL-10 predominant responses are associated with progression to chronic hepatitis C virus infection in injecting drug users

(2010) J. K. Flynn et al.   JOURNAL OF VIRAL HEPATITIS

Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression

(2010) A. Bergthaler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells

(2009) M. A. Brockman et al.   BLOOD

The diversity of costimulatory and inhibitory receptor pathways and the regulation of antiviral T cell responses

(2009) Alison Crawford et al.   CURRENT OPINION IN IMMUNOLOGY

A Vital Role for Interleukin-21 in the Control of a Chronic Viral Infection

(2009) J. S. Yi et al.   SCIENCE

IL-21 Is Required to Control Chronic Viral Infection

(2009) H. Elsaesser et al.   SCIENCE

IL-10 blockade facilitates DNA vaccine-induced T cell responses and enhances clearance of persistent virus infection

(2008) David G. Brooks et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis

(2008) Jiyun V. Kim et al.   NATURE

IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection

(2008) D. G. Brooks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA