Article
Instruments & Instrumentation
E. Peng, Wenbin Ling, Aohua Mao, Chenggang Jin, Qingmei Xiao, Fengyu Xu, Chunxi Chen, Xiangchun Bai, Huiping Hao, Yaowen Lu, Yongxing Xu, Guangliang Zhu, Xudong Weng, Bing Lin
Summary: A magnet system is utilized in the SPERF to generate magnetic field configurations for simulating space plasma environments. The study focuses on designing system parameters to achieve target fields, conducting electromagnetic analysis for validation, and proposing a parameter determination procedure. Calculations of vacuum magnetic fields for studying 3D magnetic reconnection and a brief review of engineering complexities were also provided, highlighting the importance of this research for SPERF construction and magnet design in other fields.
REVIEW OF SCIENTIFIC INSTRUMENTS
(2021)
Article
Physics, Fluids & Plasmas
Michele Mugnaine, Matheus Rolim Sales, Jose Danilo Szezech, Ricardo Luiz Viana
Summary: In this study, we introduce a one-dimensional dynamical system called the sine-circle nontwist map, which serves as a local approximation of the standard nontwist map and an extension of the paradigmatic sine-circle map. By analyzing the parameters of the map, we identify periodic, quasiperiodic, and chaotic solutions. We also investigate the multistability and observe the coexistence of different attractors, as well as the influence of boundary crisis on multistability.
Article
Engineering, Aerospace
Alexander P. Yefremov, Alexandra A. Vorobyeva
Summary: A space experiment can test the nature of gravitational fields in the solar system, with differences in the final positions of a probe serving as a definitive measure of the accuracy of different theories of gravity.
Article
Mathematics
Remus-Daniel Ene, Nicolina Pop
Summary: The goal of this work is to develop semi-analytical solutions for the Rikitake-type system using the optimal homotopy perturbation method. The obtained closed-form solutions exhibit periodic behavior and have been validated for different physical parameters. The advantages of the method, such as efficiency, convergence control, and effective representation of solutions, have been demonstrated.
Article
Engineering, Aerospace
Alexander P. Yefremov, Alexandra A. Vorobyeva
Summary: A planetary model simulating the Sun, Venus, and Earth was constructed to investigate the gravity assist effect of Venus on a ballistic space probe sent from Earth's orbit. The study found that the Venus gravity assist can amplify changes in the probe's impact parameter caused by different physical reasons, highlighting its potential for detecting small physical effects and verifying gravity theories.
Article
Mathematics, Applied
Cesar Manchein, Bianca Fusinato, Hugne S. Chagas, Holokx A. Albuquerque
Summary: Single-walled carbon nanotubes (SWCNTs) exhibit large nonlinear deformations without permanent damage and have important implications in science and technology. This study investigates the nonlinear dynamics of a curved SWCNT oscillator model when two control parameters are varied simultaneously. The study identifies the existence of a quint points lattice merged in a domain of periodic dynamics, the coexistence of different stable states for the same parameter combinations and different initial conditions, and the existence of infinite self-organized generic stable periodic structures (SPSs) merged into chaotic dynamics domains. The findings highlight the complexity of the dynamics in damped-driven curved SWCNTs and its potential impact on theoretical and experimental applications.
Article
Physics, Condensed Matter
Vinicius Wiggers, Paulo C. Rech
Summary: In this paper, an autonomous snap oscillator derived from the Van der Pol-Duffing forced oscillator is proposed and its dynamics are investigated. Through numerical simulations and parameter plane analysis, the chaotic and periodic behavior of the system is explored in certain parameter regions. The basins of attraction and coexisting attractors are analyzed and the stability of equilibrium points is studied analytically.
EUROPEAN PHYSICAL JOURNAL B
(2022)
Article
Computer Science, Artificial Intelligence
Mubashir Qayyum, Efaza Ahmad, Aneeza Tahir, Saraswati Acharya
Summary: This paper presents a fuzzy-fractional financial chaotic model to predict the impact of long-term dependency and uncertainty on financial markets. The proposed He-Mohand algorithm combines homotopy perturbation with Mohand transform to provide solutions. Numerical results and graphical analysis demonstrate the reliability, efficiency, and physical behavior of the model.
INTERNATIONAL JOURNAL OF INTELLIGENT SYSTEMS
(2023)
Article
Automation & Control Systems
Marina B. A. Souza, Leonardo de Mello Honorio, Edimar Jose de Oliveira
Summary: This paper analyzes the influence of the solution space of a nonlinear dynamic system on the quality of parameter estimation, proposing an approach that uses Optimal Input Design for parameter estimation. The method is analyzed in terms of its applications, qualities, and limitations in the context of the solution space. Through a detailed analysis of the identification process of a differential mobile robot, the paper serves as a reference for selecting the most suitable model for the identification process.
INTERNATIONAL JOURNAL OF CONTROL AUTOMATION AND SYSTEMS
(2021)
Article
Engineering, Mechanical
Ling Liu, Francesco Ripamonti, Roberto Corradi, Zhushi Rao
Summary: This paper proposes a methodology for experimental vibroacoustic modal analysis on a coupled plate-cavity system. The method utilizes nonlinear curve fitting to analyze Frequency Response Functions (FRFs) obtained through a roving hammer test. The FRFs are divided into two groups for the acceleration of the plate and the sound pressure inside the cavity. The methodology successfully overcomes identification difficulties caused by slight changes in natural frequencies and simplifies the extraction of mode shapes by considering the different scales between structural and acoustic responses. The proposed FRF models accurately fit the measured FRFs and provide a practical and efficient approach for experimental modal analysis of vibroacoustic systems.
MECHANICAL SYSTEMS AND SIGNAL PROCESSING
(2022)
Article
Mathematics, Interdisciplinary Applications
Xiaofeng Wang, Xiaohe Chen
Summary: This paper analyzes a family of Ostrowski-type iterative schemes with a biparameter and studies their dynamic properties and stability. By visualizing the parameter spaces, the most stable member of the biparametric family of six-order Ostrowski-type methods is identified.
FRACTAL AND FRACTIONAL
(2022)
Article
Mathematics
Meng Liu, Zhaoyan Wu, Xinchu Fu
Summary: In this paper, a three-dimensional autonomous chaotic system is introduced and analyzed. The system is capable of generating different types of chaotic attractors by adjusting its parameters. The basic dynamical properties of the system are studied, and corresponding electronic circuits are designed for parameter identification or monitoring.
Article
Astronomy & Astrophysics
G. Papagiannopoulos, Spyros Basilakos, Emmanuel N. Saridakis
Summary: In this study, we analyze the dynamical system of Myrzakulov or F(R, T) gravity, focusing on its subclasses and their critical points. We examine the stability and physical features of these models. Our findings show that in class 1 models, the Universe will result in a dark-energy-dominated critical point, while in class 2 models, the behavior of dark energy can be more varied.
Article
Mathematics, Applied
Hai-Liang Li, Tong Yang, Mingying Zhong
Summary: This paper provides a detailed spectrum analysis of the linearized Vlasov-Poisson-Boltzmann system around a global Maxwellian by identifying a norm capturing the effect of the forcing governed by the Poisson equation. The role of the electric field governed by the self-consistent Poisson equation is highlighted in the analysis, leading to a genuinely different spectrum structure compared to the well-known one of the Boltzmann equation. Optimal time decay rates of solutions to the equilibrium are determined based on this analysis.
ARCHIVE FOR RATIONAL MECHANICS AND ANALYSIS
(2021)
Article
Construction & Building Technology
Gianluca Coccia, Serena Summa, Elisa Di Giuseppe, Marco D'Orazio, Michele Zinzi, Costanzo Di Perna
Summary: Due to climate change, urban overheating has increased worldwide in recent decades. Therefore, it is essential to promote effective solutions to mitigate overheating at a micro-scale level. In this study, a modular experimental setup with a water spray system was designed and tested to evaluate its thermohygrometric performance in semi-outdoor spaces. The setup allows for adjusting three operational parameters and evaluating the performance of different configurations for the water spray system. The results showed that the best configuration reduced the dry-bulb temperature by 20% and had minimal water and electricity consumption.
BUILDING AND ENVIRONMENT
(2023)
Article
Biotechnology & Applied Microbiology
Rodrigo A. da Silva, Georgia da Silva Feltran, Marcel Rodrigues Ferreira, Patricia Fretes Wood, Fabio Bezerra, Willian F. Zambuzzi
BIOMED RESEARCH INTERNATIONAL
(2020)
Article
Developmental Biology
Rahyza I. F. Assis, Georgia da S. Feltran, Maria Eduarda Salomao Silva, Iasmin Caroline do Rosario Palma, Emanuel Silva Rovai, Tais Browne de Miranda, Marcel Rodrigues Ferreira, Willian F. Zambuzzi, Alexander Birbrair, Denise C. Andia, Rodrigo A. da Silva
Summary: Mesenchymal stem cells in the periodontal ligament exhibit differential osteogenic potential, with high-PDLCs showing stronger osteogenic capacity. Epigenetic markers and non-coding RNAs, particularly miRs and lncRNAs, play important roles in regulating the expression of osteogenic-related genes like RUNX2. Understanding the distinct transcriptional profiles of lncRNAs and biogenesis machinery in PDLCs can help uncover the underlying mechanisms of osteogenesis.
DEVELOPMENTAL BIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Rahyza I. F. Assis, Arthur G. Schmidt, Francesca Racca, Rodrigo A. da Silva, William F. Zambuzzi, Karina G. Silverio, Francisco H. Nociti, Vanessa G. Pecorari, Malgorzata Wiench, Denise C. Andia
Summary: This study investigated the heterogeneity in osteogenic potential of periodontal ligament cells (PDLCs) and explored the enhancement of osteogenic differentiation through epigenetic modulation. The findings suggest a role of DNMTs and TETs in osteogenic commitment, supporting the potential application of epigenetic approaches in regulating biomineralization in PDLCs.
DNA AND CELL BIOLOGY
(2021)
Review
Oncology
Walison N. Silva, Alinne C. Costa, Caroline C. Picoli, Beatriz G. S. Rocha, Gabryella S. P. Santos, Pedro A. C. Costa, Parviz Azimnasab-sorkhabi, Maryam Soltani-asl, Rodrigo A. da Silva, Jaime Henrique Amorim, Rodrigo R. Resende, Akiva Mintz, Alexander Birbrair
Summary: Recent studies using advanced technologies have successfully visualized endogenous hematopoietic stem cells in live animals, revealing that quiescent stem cells are more mobile than previously thought. This new understanding is crucial for research on hematopoietic stem cells and the treatment of various hematological diseases.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Rogerio S. Ferreira, Rahyza I. F. Assis, Georgia da S. Feltran, Iasmin Caroline do Rosario Palma, Beatriz G. Francoso, Willian F. Zambuzzi, Denise C. Andia, Rodrigo A. da Silva
Summary: The study investigated the impact of individual epigenetic and transcriptional profiles on osteogenic potential using mesenchymal cells from periodontal ligament. Results showed distinct epigenetic and transcriptional differences among PDLCs, which were maintained after osteogenic induction. These findings suggest that individual donor characteristics have a significant impact on the acquisition of the osteogenic phenotype.
JOURNAL OF PERIODONTOLOGY
(2022)
Article
Multidisciplinary Sciences
Vincent T. Janmaat, Kateryna Nesteruk, Manon C. W. Spaander, Auke P. Verhaar, Bingting Yu, Rodrigo A. Silva, Wayne A. Phillips, Marcin Magierowski, Anouk van de Winkel, H. Scott Stadler, Tatiana Sandoval-Guzman, Luc J. W. van der Laan, Ernst J. Kuipers, Ron Smits, Marco J. Bruno, Gwenny M. Fuhler, Nicholas J. Clemons, Maikel P. Peppelenbosch
Summary: The expression of the distal HOX gene HOXA13 in Barrett's esophagus is proposed to underlie the phenotypic aspects of metaplasia and increased proliferation. This expression may confer a competitive advantage to cells and contribute to the expansion of the gastro-esophageal HOXA13-expressing compartment, leading to the development of Barrett's esophagus and associated esophageal adenocarcinoma. Barrett's esophagus is described as a pro-oncogenic lesion in the proximal gastrointestinal tract with a distal colon-like morphology.
NATURE COMMUNICATIONS
(2021)
Article
Anatomy & Morphology
Celio Junior da C. Fernandes, Rodrigo A. da Silva, Patricia Fretes Wood, Suelen Aparecida Teixeira, Fabio Bezerra, Willian F. Zambuzzi
Summary: This study reveals, for the first time, the epigenetic-related molecular mechanism involved in endothelial cells responding to zirconia. The signaling pathways triggered by zirconia seem to culminate in cytoskeleton rearrangement of endothelial cells, a prerequisite to cell migration expected in angiogenesis. The study demonstrates a repertoire of signaling molecules capable of executing the reprogramming process of gene expression in endothelial cells, necessary for cell proliferation, migration, and angiogenesis.
Article
Cell Biology
Rahyza I. F. Assis, Francesca Racca, Rogerio S. Ferreira, Karina G. S. Ruiz, Rodrigo A. da Silva, Samuel J. H. Clokie, Malgorzata Wiench, Denise C. Andia
Summary: Periodontal ligament stem cells (PDLCs) have the potential to be used in cell therapies for bone tissue regeneration, but their heterogeneity in terms of osteoblast differentiation and mineral nodule production makes the therapeutic outcomes unpredictable. This study identified epigenetic, chromatin, and transcriptional differences between PDLCs with low and high osteogenic potential, and suggested that these differences could be used to select PDLCs with a pre-osteoblastic phenotype.
Review
Biochemistry & Molecular Biology
Jennyffer Souza, Rodrigo Augusto da Silva, Debora da Luz Scheffer, Rafael Penteado, Alexandre Solano, Leonardo Barros, Henning Budde, Andres Trostchansky, Alexandra Latini
Summary: Regular physical exercise has been shown to enhance cellular antioxidant defenses by activating the NRF2 signaling pathway, which in turn has beneficial effects on the antioxidant systems in both the brain and skeletal muscle.
Article
Environmental Sciences
Maciel Alencar Bruxel, Flavia Natividade da Silva, Rodrigo Augusto da Silva, Priscila Laiz Zimath, Anabel Rojas, Eduardo Luis Gasnhar Moreira, Ivan Quesada, Alex Rafacho
Summary: The study explores the impact of pre-pregnancy exposure to the organophosphate insecticide malathion on glucose homeostasis during pregnancy and the potential consequences for both mothers and offspring.
ENVIRONMENTAL POLLUTION
(2023)
Article
Biochemistry & Molecular Biology
Tuany Eichwald, Alexandre Francisco Solano, Jennyffer Souza, Tais Browne de Miranda, Liebert Bernardes Carvalho, Paula Lemes dos Santos Sanna, Rodrigo A. Foganholi da Silva, Alexandra Latini
Summary: Caffeine administration reduces expression of pro-inflammatory biomarkers and promotes an anti-inflammatory response. It also upregulates adenosinergic receptors and affects DNA methylation patterns. Caffeine treatment attenuates the catabolic state induced by lipopolysaccharide. These effects suggest that caffeine's anti-inflammatory effects in muscle may be mediated through epigenetic modifications.
Article
Engineering, Biomedical
Celio Junior da C. Fernandes, Rodrigo A. Foganholi da Silva, Gerson Santos de Almeida, Marcel Rodrigues Ferreira, Paula Bertin de Morais, Fabio Bezerra, Willian F. Zambuzzi
Summary: Emerging Cobalt-chromium (Co-Cr)-based alloys show important characteristics for use in dentistry, but the understanding of epigenetic mechanisms in endothelial cells is limited. This study reveals the involvement of epigenetic machinery and the finely modulated methylation balance in response to Co-Cr. DNMTs (DNA methyltransferases) and TETs (Tet methylcytosine dioxygenases), especially DNMT3B and TET1/TET2, play significant roles. Additionally, HDAC6 (histone deacetylase 6) and SIRT1 are found to have effects in endothelial cells, with SIRT1 playing a crucial role. The study highlights the importance of epigenetic machinery in the response of endothelial cells to Co-Cr and provides new perspectives for understanding its impact on cell adhesion, cell cycle progression, and angiogenesis.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Genetics & Heredity
Rogerio S. Ferreira, Rahyza I. F. Assis, Francesca Racca, Ana Carolina Bontempi, Rodrigo A. da Silva, Malgorzata Wiench, Denise C. Andia
Summary: In this study, the epigenetic patterns of the SP7 and DLX4 osteoblastic transcription factors were investigated in human periodontal ligament mesenchymal cells (PDLCs) with low and high osteogenic potential. The results showed that the lncRNAs MIR31HG and LINC00939 were upregulated in l-PDLCs and may inhibit osteogenic differentiation by repressing the SP7 and DLX4 transcription factors at the (post)transcriptional and translational levels.
Article
Dentistry, Oral Surgery & Medicine
Rogerio S. Ferreira, Rodrigo A. da Silva, Georgia Da S. Feltran, Ericka Patricia da Silva, Rahyza I. F. de Assis, Emanuel Silva Rovai, Willian F. Zambuzzi, Denise C. Andia
Summary: The results of this study demonstrate the crucial role of JARID1B in repressing the osteogenic phenotype of PDLCs, suggesting its potential as a therapeutic target in pre-clinical protocols.
Article
Cell & Tissue Engineering
Caroline C. Picoli, Alinne C. Costa, Beatriz G. S. Rocha, Walison N. Silva, Gabryella S. P. Santos, Pedro H. D. M. Prazeres, Pedro A. C. Costa, Anderson Oropeza, Rodrigo A. da Silva, Vasco A. C. Azevedo, Rodrigo R. Resende, Thiago M. Cunha, Akiva Mintz, Alexander Birbrair
Summary: Niches in tissue microenvironments play a crucial role in regulating stem cell function. Recent studies have identified sensory neurons as an important component of the bone marrow mesenchymal stem cell niche, influencing stem cell fate and function. Understanding the biology of sensory nerves in the stem cell niche will be essential for future stem cell manipulation.
STEM CELLS TRANSLATIONAL MEDICINE
(2021)
