Newly Recruited CD11b+, GR-1+, Ly6ChighMyeloid Cells Augment Tumor-Associated Immunosuppression Immediately following the Therapeutic Administration of Oncolytic Reovirus

Reovirus Activates Human Dendritic Cells to Promote Innate Antitumor Immunity

(2014) Fiona Errington et al.   JOURNAL OF IMMUNOLOGY

Oncolytic Virus-Mediated Reversal of Impaired Tumor Antigen Presentation

(2014) Shashi A. Gujar et al.   Frontiers in Oncology

Increased Frequency of Myeloid-derived Suppressor Cells during Active Tuberculosis and after RecentMycobacterium tuberculosisInfection Suppresses T-Cell Function

(2013) Nelita du Plessis et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Gemcitabine enhances the efficacy of reovirus-based oncotherapy through anti-tumour immunological mechanisms

(2013) S A Gujar et al.   BRITISH JOURNAL OF CANCER

Chronic but Not Acute Virus Infection Induces Sustained Expansion of Myeloid Suppressor Cell Numbers that Inhibit Viral-Specific T Cell Immunity

(2013) Brian A. Norris et al.   IMMUNITY

Myeloid derived suppressor cells in physiological and pathological conditions: the good, the bad, and the ugly

(2013) Paolo Serafini   IMMUNOLOGIC RESEARCH

Myeloid-derived suppressor cells: the dark knight or the joker in viral infections?

(2013) Celeste Goh et al.   IMMUNOLOGICAL REVIEWS

Reciprocal Relationship between Myeloid-Derived Suppressor Cells and T Cells

(2013) S. Nagaraj et al.   JOURNAL OF IMMUNOLOGY

Multifaceted Therapeutic Targeting of Ovarian Peritoneal Carcinomatosis Through Virus-induced Immunomodulation

(2013) Shashi Gujar et al.   MOLECULAR THERAPY

Maraba Virus as a Potent Oncolytic Vaccine Vector

(2013) Jonathan G Pol et al.   MOLECULAR THERAPY

Cancer Immunotherapy

(2013) J. Couzin-Frankel   SCIENCE

Getting to Know Ovarian Cancer Ascites: Opportunities for Targeted Therapy-Based Translational Research

(2013) Nuzhat Ahmed et al.   Frontiers in Oncology

NK Cell Response to Vaccinia Virus Is Regulated by Myeloid-Derived Suppressor Cells

(2012) C. Fortin et al.   JOURNAL OF IMMUNOLOGY

Myeloid-Derived Suppressor Cells Regulate Natural Killer Cell Response to Adenovirus-Mediated Gene Transfer

(2012) J. Zhu et al.   JOURNAL OF VIROLOGY

Expansion of Monocytic Myeloid-Derived Suppressor Cells Dampens T Cell Function in HIV-1-Seropositive Individuals

(2012) Aiping Qin et al.   JOURNAL OF VIROLOGY

Reovirus: A Targeted Therapeutic--Progress And Potential

(2012) R. Maitra et al.   MOLECULAR CANCER RESEARCH

Immunology beats cancer: a blueprint for successful translation

(2012) Drew M Pardoll   NATURE IMMUNOLOGY

Instruction of myeloid cells by the tumor microenvironment: Open questions on the dynamics and plasticity of different tumor-associated myeloid cell populations

(2012) Elio Schouppe et al.   OncoImmunology

Myeloid suppressor cells induced by hepatitis C virus suppress T-cell responses through the production of reactive oxygen species

(2011) Robert S. Tacke et al.   HEPATOLOGY

Oncolytic Virus-initiated Protective Immunity Against Prostate Cancer

(2011) Shashi A Gujar et al.   MOLECULAR THERAPY

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE

Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity

(2010) Suzanne Ostrand-Rosenberg   CANCER IMMUNOLOGY IMMUNOTHERAPY

Myeloid-derived suppressor cells in parasitic infections

(2010) Jo A. Van Ginderachter et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Ovarian cancer immunotherapy: opportunities, progresses and challenges

(2010) Bei Liu et al.   Journal of Hematology & Oncology

Mycobacterium bovis Bacillus Calmette-Guérin Vaccination Mobilizes Innate Myeloid-Derived Suppressor Cells Restraining In Vivo T Cell Priming via IL-1R–Dependent Nitric Oxide Production

(2010) Angelo Martino et al.   JOURNAL OF IMMUNOLOGY

Mechanism of T Cell Tolerance Induced by Myeloid-Derived Suppressor Cells

(2010) S. Nagaraj et al.   JOURNAL OF IMMUNOLOGY

Reovirus Virotherapy Overrides Tumor Antigen Presentation Evasion and Promotes Protective Antitumor Immunity

(2010) S. A. Gujar et al.   MOLECULAR CANCER THERAPEUTICS

Myeloid-Derived Suppressor Cells Inhibit T-Cell Activation by Depleting Cystine and Cysteine

(2009) M. K. Srivastava et al.   CANCER RESEARCH

Immune-Mediated Antitumor Activity of Reovirus Is Required for Therapy and Is Independent of Direct Viral Oncolysis and Replication

(2009) R. J. Prestwich et al.   CLINICAL CANCER RESEARCH

Gr-1 antibody induces STAT signaling, macrophage marker expression and abrogation of myeloid-derived suppressor cell activity in BM cells

(2009) Eliana Ribechini et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice

(2009) Hanh K. Le et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Innate Immune CD11b+Gr-1+ Cells, Suppressor Cells, Affect the Immune Response during Theiler's Virus-Induced Demyelinating Disease

(2009) J. L. Bowen et al.   JOURNAL OF IMMUNOLOGY

Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer

(2009) S. Ostrand-Rosenberg et al.   JOURNAL OF IMMUNOLOGY

Tumor Infection by Oncolytic Reovirus Primes Adaptive Antitumor Immunity

(2008) R. J. Prestwich et al.   CLINICAL CANCER RESEARCH

Invariant NKT cells reduce the immunosuppressive activity of influenza A virus–induced myeloid-derived suppressor cells in mice and humans

(2008) Carmela De Santo et al.   JOURNAL OF CLINICAL INVESTIGATION