期刊
CHINESE JOURNAL OF CHEMISTRY
卷 31, 期 6, 页码 764-772出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cjoc.201300120
关键词
alcohols; CO cross coupling; heteroaryl ethers; heteroaryl halides; phenols; transition metal-free
资金
- NNSFC [20902070]
- SRF for ROCS of SEM
- ZJNSF [Y4100579]
- ZJQJTP [QJD0902004]
- Xinmiao Talents Program of Zhejiang Province [2011R424019]
By optimizing the reaction conditions via a careful screening of the bases and solvents, we developed an efficient transition metal-free method for CO cross-coupling of activated and unactivated heteroaryl chlorides with primary and secondary alcohols and phenols, providing a simple, efficient, and practical method for synthesis of the useful unsymmetrical heteroaryl alkyl and heteroaryl aryl ethers.
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