4.5 Article

Stereoselective Synthesis of 1-Aminocyclopropanecarboxylic Acid Derivatives via Ylide Cyclopropanation of Dehydroamino Acid Derivatives

期刊

CHINESE JOURNAL OF CHEMISTRY
卷 29, 期 5, 页码 995-1000

出版社

WILEY-BLACKWELL
DOI: 10.1002/cjoc.201190202

关键词

amino acids; enantioselectivity; annulation; ylides; stereoselective synthesis

资金

  1. National Natural Science Foundation of China [20821002, 20932008]
  2. Major State Basic Research Development Program [2009CB825300]
  3. Science and Technology Commission of Shanghai Municipality [Y0D00512E0]

向作者/读者索取更多资源

1-Aminocyclopropanecarboxylic acid derivatives are synthesized from readily available dehydroamino acid derivatives via sulfur ylide. A range of different ylides are employed and the corresponding aminocyclopropanes are afforded with reasonable diastereoselection in good yields.

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