期刊
CHINESE CHEMICAL LETTERS
卷 25, 期 3, 页码 469-473出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2013.12.022
关键词
Silica-bonded N-propyl sulfamic acid; 3,4-Dihydropyrimidin-2-(1H)-ones; Multi component reactions; Heterogeneous catalysis
资金
- Madhya Pradesh Council of Science & Technology (MPCOST, Bhopal)
Silica-bonded N-propyl sulfamic acid (SBNPSA) catalyzed one-pot three component Biginelli condensation of different substituted aromatic aldehydes with ethyl acetoacetate and urea/thoiurea to the respective 3,4-dihydropyrimidin-2-(1H)-ones and thiones in environment friendly procedure is described. The facile reaction conditions, simple isolation and purification procedures of this method make it a good option for the synthesis of dihydropyrimidinones. (C) 2013 Srinivasa Rao Jetti. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
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