Article
Biochemistry & Molecular Biology
Li-Guo Liao, Meng-Meng Song, Jun-Feng Feng, Min Tan, Fan Liu, Zhen-Jiang Qiu, Sheng Zhang, Bang-Jing Li
Summary: An efficient, mild, and green method has been developed for the synthesis of indeno[1,2-b]quinoxaline derivatives using beta-cyclodextrin as the supramolecular catalyst. The reaction can be performed in water or in a solid state at room temperature. Compared to reported methods, this procedure is milder, simpler, and less toxic, providing an eco-friendly alternative. Furthermore, beta-cyclodextrin can be recovered and reused without losing its activity.
Article
Chemistry, Multidisciplinary
Shankar D. Dhengale, Chandrashekhar Rode, Govind B. Kolekar, Prashant Anbhule
Summary: A simple method for the synthesis of indeno-[1,2-b]-quinoline-9,11-(6H,10H)-dione derivatives and 7,7-dimethyl-10-aryl-7,8-dihydro-5H-indeno[1,2-b]quinoline-9,11(6H,10H)-diones has been investigated. The reaction involves the use of aromatic aldehydes, indan-1,3-dione, dimedone, and p-toluidine/ammonium acetate in the presence of a CuO catalyst supported on zeolite-Y in ethanol under reflux conditions. The catalyst showed both Bronsted acid sites and Lewis acid sites, and could be recycled with minimal decrease in yield up to five recycles.
Article
Chemistry, Multidisciplinary
Kowit Hengphasatporn, Thitinan Aiebchun, Panupong Mahalapbutr, Atima Auepattanapong, Onnicha Khaikate, Kiattawee Choowongkomon, Chutima Kuhakarn, Jatuporn Meesin, Yasuteru Shigeta, Thanyada Rungrotmongkol
Summary: This study investigated the kinase inhibitory activities of a series of sulfonylated indeno-[1,2-c]-quinolines (SIQs) against EGFR-TK. Among the 23 SIQ derivatives studied, eight compounds showed enhanced EGFR-TK inhibitory activity compared to erlotinib. In cell-based assays, these eight compounds exhibited more significant cytotoxicity against A431 cells with higher EGFR expression. Overall, the potent SIQ compounds obtained in this work could be further optimized for developing novel anticancer drug candidates targeting EGFR-TK.
Article
Chemistry, Physical
Jiangjie Zhang, Jun Ying, Xiao-Feng Wu
Summary: A novel palladium-catalyzed tandem cyclization and carbonylation reaction was developed for the synthesis of indeno[1,2-b]indol-10(5H)-one derivatives. The reaction proceeded smoothly with high yields using formic acid as the CO source. This method can also be applied for the modification of various bioactive molecules.
JOURNAL OF CATALYSIS
(2023)
Article
Chemistry, Multidisciplinary
Athukuri Edukondalu, Sandip Sambhaji Vagh, Ting-Han Lin, Wenwei Lin
Summary: An efficient protocol for the chemoselective construction of indeno[1,2-b]pyrroles and rearranged derivatives has been reported via an N-acylation/cyclization/Wittig reaction. Mechanistic investigations revealed the crucial role of a spiro-indene-1,2'-[1,3,4]oxadiazol intermediate and its further reaction with phosphine to generate betaine, leading to the formation of the targeted heteroarenes predominantly through a Wittig reaction.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Leila Najafi, Javad Safaei-Ghomi, Hourieh Sadat Oboudatian
Summary: In this study, acidic nanosilica spheres were prepared and used as a catalyst for the synthesis of indeno[1,2-b]quinolinone derivatives. The nanocatalyst exhibited high surface area, uniform mesoporous structure, high thermal stability, recyclability, nontoxicity, and easy separation. The synthesis reaction showed excellent yields with short reaction times, cost savings, and low catalyst loading.
Article
Environmental Sciences
Jin Wang, Jihui Zhang, Yahui Song, Xianmang Xu, Mengyun Cai, Peichuang Li, Wenpeng Yuan, Yujiao Xiahou
Summary: In this research, a highly recyclable catalyst of Ag-based agarose hydrogel was successfully fabricated through a simple reduction method. The hydroxyl functional groups in agarose effectively control the growth and dispersion of Ag nanoparticles in the hydrogel, ensuring the reusability of the catalyst. The hydrogel showed great potential as a catalyst for reducing aromatic organic pollutants, achieving high conversion rates and efficient reduction of various pollutants.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Chemistry, Inorganic & Nuclear
Ntakadzeni Madima, Kebede K. Kefeni, Shivani B. Mishra, Ajay K. Mishra, Alex T. Kuvarega
Summary: This study successfully synthesized magnetic Fe3O4/TiO2 nanocomposites as efficient and recyclable photocatalysts for degrading rhodamine B pollutants under simulated solar light. By optimizing factors such as Fe3O4 loading, photocatalyst properties, and reuse cycles, the photocatalytic activity and stability were improved.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Mina Zare, Leila Moradi
Summary: In this study, magnetic mesoporous N-doped silica nanospheres decorated by CuO nanoparticles (M-MNS/CuO) were prepared and used for the green and efficient synthesis of [3.3.3] propellane indeno[1,2-b] indole derivatives. The catalyst has dual acidic and basic properties due to the presence of nitrogen atoms and copper oxide nanoparticles in its structure.
Article
Chemistry, Multidisciplinary
Martin Ek, Logi Arnarson, Poul Georg Moses, Soren B. Rasmussen, Magnus Skoglundh, Eva Olsson, Stig Helveg
Summary: The research found that there are differences in the redox properties of vanadium oxide nanoparticles on different crystal facets, with vanadium ions on {001} facets maintaining higher oxidation states than on {10l} facets. This sensitivity to surface structure in redox processes opens up new possibilities for tailoring oxide nanoparticles for enhanced catalytic functionalities.
Article
Chemistry, Organic
Zhicong Tang, Gang Hong, Chen Hu, Qi Wang, Yi Zhong, Yu Gong, Peng Yang, Limin Wang
Summary: The Lewis acid-promoted self-condensation of 2-indolylmethanols has been demonstrated to synthesize highly substituted indeno[1,2-b]indole derivatives with up to 94% yields. The photophysical properties of the prepared products suggest potential applications in the construction of novel fluorescent materials.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2021)
Article
Chemistry, Physical
Wenzheng Chen, Xuezhang Xiao, Jiahuan He, Zhong Dong, Xuancheng Wang, Man Chen, Lixin Chen
Summary: A novel dandelion-like CoMoNi-B/ZIF-67 catalyst was developed with excellent performance in catalyzing the hydrolysis of sodium borohydride, showing great potential for widespread application in hydrogen generation.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2021)
Article
Chemistry, Organic
Wang Jing, Wu Linli, Wang Qian
Summary: Indeno fluorene-6,12-dione derivatives 5 were synthesized by modifying 2,5-dibromo-p-xylene and phenylboronic acid derivatives. The introduction of alkyl chains improved the solubility of the compounds and the effects of systematic substitution variation on their properties were investigated. The new compounds showed better solubility, thermal and optical stability than pentacene. The molecular packing of 2,8Diisopropylindeno[1,2-b]fluorene-6,12-dione (5b) and 2,8-dibutylindeno[1,2-b]fluorene-6,12-dione (5c) facilitated carrier transport.
CHINESE JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Serhii A. Liakhov, Igor A. Schepetkin, Olexander S. Karpenko, Hanna Duma, Nadiia M. Haidarzhy, Liliya N. Kirpotina, Anastasia R. Kovrizhina, Andrei Khlebnikov, Irina Y. Bagryanskaya, Mark T. Quinn
Summary: In this study, 13 derivatives of a JNK inhibitor were synthesized, with 8 compounds showing submicromolar binding affinity for at least one JNK isoform, and most of them exhibiting anti-inflammatory effects. Selected compounds also directly confirmed JNK inhibition, indicating their potential as lead compounds for anti-inflammatory drug development.
Article
Engineering, Environmental
Yu Yang, Zhuangzhuang Chu, Qiyao Huang, Yongtao Li, Bin Zheng, Jian Chang, Zhuohong Yang
Summary: A nickel-coated hyperporous polymer foam (Ni-HPF) was designed and fabricated with hierarchical multiscale porous structures and abundant catalytical interfaces, showing high conversion efficiency and rapid reaction rate for treating organic 4-nitrophenol pollutants. The magnetic catalyst also demonstrated excellent recoverability and reproducibility, indicating potential applications in water purification, chemical catalysis, and energy storage devices.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Qian Wu, Yubo Cui, Guifeng Xia, Jinlong Yang, Shuming Du, Xinhong Xiong, Li Yang, Dong Xu, Xu Deng, Jiaxi Cui
Summary: Passive daytime radiative cooling (PDRC) technology, while promising for global spacing cooling, faces limitations in practical application due to reduced cooling effectiveness caused by wear and dirt contamination. Researchers have developed a renewable armor structure using fluorinated hollow glass microspheres to enhance the anti-fouling and cooling properties of PDRC coatings. The coatings exhibit high solar reflectance and thermal emittance, leading to significant temperature reduction below ambient temperature.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Qiang Bei, Bei Zhang, Kaifeng Wang, Shiming Zhang, Guichuan Xing, Clement Cabanetos
Summary: The power conversion efficiency (PCE) of organic solar cells (OSCs) has reached 20% in recent years, thanks to the advantages of organic photoactive materials. Benzothiadiazole (BT) has attracted significant research attention as a building block of OSCs. OSCs based on BT structure have shown diversity, and the increasing PCE values indicate a promising future for OSCs. This review analyzes the progress made in the last decades, focusing on effective BT small-molecules and BT polymers for OSCs. The structure-property relationships, donor-acceptor matching criteria, and morphology control approaches are discussed. The remaining challenges and a personal perspective on the future advancement of OSCs are summarized.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Rong He, Dandan Tang, Ningge Xu, Heng Liu, Kun Dou, Xuejun Zhou, Fabiao Yu
Summary: Nasopharyngeal carcinoma (NPC) is a common malignant tumor of the head and neck, with a high incidence in China and Southeast Asian countries. In this study, a novel near-infrared fluorescent probe, SNAFL-GSH, was designed and synthesized for the detection of glutathione (GSH). The probe showed selective detection of GSH and the ability to distinguish normal and cancer cells. It has great potential for application in the diagnosis and evaluation of NPC.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Zhukang Guo, Baijiang Jin, Yile Fang, Lian Jin, Song Li, Yan Deng, Zhu Chen, Hui Chen, Yuanying Zhang, Rabia Usman, Nongyue He
Summary: This study isolated primary cells that can be stably passaged from spontaneous tumors of genetically engineered pancreatic ductal adenocarcinoma model mice and used an autonomously developed automated screening instrument for efficient nucleic acid aptamer screening. The obtained aptamers were affinity verified at the cellular level. The study also investigated the impact of cell growth environment difference on the recognition ability of aptamers and confirmed the targeting ability and drug loading ability of the aptamer.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Zhongshan Yang, Qiqi Zhang, Hui Song, Xin Chen, Jiwei Cui, Yanhui Sun, Lequan Liu, Jinhua Ye
Summary: Methane chemistry is a significant area of research in catalysis. Converting methane into value-added chemicals is desirable but challenging due to its high C-H bonding energy and lack of pi bonding or unpaired electrons. Photocatalytic partial oxidation of methane to liquid oxygenates is a promising technology for achieving high efficiency and selectivity under mild conditions. The choice and activation of oxidants are crucial for its performance.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Peng Shan, Jing Liao, Jiayi Li, Chengyan Wang, Jie Zhou, Linqiang Mei, Yunlu Dai, Qiang Wang, Wenyan Yin
Summary: This study reports an oral radioprotectant Gel@GYY that combines a gelatin-based hydrogel and a pH-responsive hydrogen sulfide donor. Gel@GYY has excellent adhesion and sustained release properties, allowing it to release H2S in the gastrointestinal tract and effectively scavenge free radicals induced by radiation. It also reduces inflammation and has biodegradable properties.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lu Liu, Ziyi Liu, Jingnan Cui, Guiling Ning, Weitao Gong
Summary: The development of new metal-free heterogeneous catalysts has been the subject of extensive research. In this study, a new Troger's base (TB)-derived porous organic polymer (POPs) was designed and prepared by integrating multifunctional monomers. The resulting polymer, which combines the advantages of pillar[5]arene macrocycle and TB moiety, exhibited enhanced catalytic performance in Knoevenagel condensation and CO2 conversion, serving as an effective metal-free catalyst. This work provides a new strategy for fabricating metal-free heterogeneous catalysts based on macrocyclic POPs.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Leyong Zhou, Changyin Yang, Weitao Dou, Tongxia Jin, Haibo Yang, Lin Xu
Summary: This review summarizes the application of micro/nanofluidic techniques in constructing supramolecular assemblies of different scales, and highlights the advantages of these techniques over conventional synthesis methods. Furthermore, it emphasizes the potential of micro/nanofluidic systems in improving our understanding of supramolecular self-assembly processes.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Yanchao Jin, Suixiaochen Chen, Peiwen Huang, Xiongjian Chen, Chun-Yan Lin, Li-Ping Li, Xiao Chen, Rui Ding, Jianxi Liu, Riyao Chen
Summary: In this study, magnesium and coconut shell carbon were used to disinfect water by adsorbing copper(II) and converting dissolved oxygen to hydrogen peroxide through Mg corrosion. The copper was enriched on the carbon surface and efficiently catalyzed the hydrogen peroxide to inactivate E.coli. The process showed promising disinfection performance both in laboratory experiments and real wastewater treatment.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Haihong Lai, Zehong Chen, Hao Zhuo, Yijie Hu, Xuan Zhao, Jiwang Yi, Hongzhi Zheng, Ge Shi, Yifan Tong, Ling Meng, Xinwen Peng, Linxin Zhong
Summary: By altering the pyrolysis route of cellulose nanofiber, the structural defects of carbon aerogels can be reduced, leading to improved compressibility and stress retention, as well as higher stress sensor sensitivity and temperature coefficient.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lina Guo, Jinsong Ding, Wenhu Zhou
Summary: Bacteria-based tumor therapy has resurfaced due to the revolution of tumor immunotherapy, offering unique solutions for traditional tumor treatments. Bacteria with active tropism can selectively colonize tumor sites and suppress tumor growth through various mechanisms, making them attractive tools for tumor treatment. This critical review introduces recent advances in bacteria-based tumor therapy, including bacterial properties, their benefits for tumor therapy, anti-tumor mechanisms, challenges, and future perspectives.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lan Liang, Chuanbin Wang, Xukai Lu, Yunan Sun, Beibei Yan, Ning Li, Guanyi Chen, Li'an Hou
Summary: This study investigates the interactions between phenol and benzaldehyde in the ECH process through experiments and theoretical calculations. The results show that phenol can accelerate the conversion of benzaldehyde, while benzaldehyde inhibits the conversion of phenol. The research provides a theoretical basis for the application of ECH in practical bio-oil upgrading.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Pengcheng Fan, Yuhao He, Junan Pan, Ning Sun, Qiyu Zhang, Chen Gu, Kang Chen, Weinan Yin, Longlu Wang
Summary: This study focuses on the recent progress in hydrogen evolution reaction (HER) based on photothermal effect. It introduces the main pathways of photothermal conversions applied in H2 evolution, summarizes the functions of the photothermal effect, and presents a method to improve the catalytic system through thermal means. The study also discusses the challenges and outlook in this promising area.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Leiduo Lai, Hongyu Zhou, Yichen Hong, Mengfan Luo, Yang Shi, Heng Zhang, Zhaokun Xiong, Gang Yao, Bo Lai
Summary: In this study, a facile ammonia reduction strategy was proposed and a novel FeVO3-x catalyst was synthesized for the activation of peroxymonosulfate (PMS) to degrade the pharmaceutical carbamazepine (CBZ). The results showed that the system could rapidly degrade CBZ and generate various active species involved in the degradation process.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Tangxin Xiao, Xiuxiu Li, Liangliang Zhang, Kai Diao, Zheng-Yi Li, Xiao-Qiang Sun, Leyong Wang
Summary: This study presents the construction of a supramolecular light harvesting system based on sequential energy transfer. The system demonstrates tunable fluorescence emission through self-assembly of polymers into nanoparticles, achieving efficient two-step light harvesting.
CHINESE CHEMICAL LETTERS
(2024)