Article
Chemistry, Applied
Sonam Sancheti, Ganapati D. Yadav
Summary: The study found that NaBr-NaBrO3 is the best brominating agent and water is the best solvent; after separation through low-temperature crystallization, unreacted material and byproducts can be recycled.
ORGANIC PROCESS RESEARCH & DEVELOPMENT
(2021)
Article
Chemistry, Multidisciplinary
Tongtong Dang, Dongfang Dong, Jiabin Zhang, Yixin He, Zhao-Yang Zhang, Tao Li
Summary: In this study, thiazolylazopyrazoles were reported as nonsymmetric bis-heteroaryl azo switches, which combine the visible-light switching character of the thiazole ring and the ease of o-substitution of the pyrazole ring. These switches can achieve (near-)quantitative visible-light isomerization in both directions and have long Z-isomer thermal half-lives of several days. Additionally, o-carbonylation of the pyrazole ring remarkably stabilizes the Z isomers through attractive intramolecular interactions.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Physical
Youcan Zhang, Yang Yuan, Hui-Qing Geng, Jian-Xing Xu, Xiao-Feng Wu
Summary: A visible light-mediated perfluoroalkylative carbonylation method using a photocatalyst system based on copper and BINAP has been developed. The method enables the synthesis of functionalized b-perfluoroalkyl esters and amides with high efficiency and excellent selectivity.
JOURNAL OF CATALYSIS
(2022)
Article
Chemistry, Organic
Zhuang Qi, Lin Li, Ying-Kang Liang, Ai-Jun Ma, Xiang-Zhi Zhang, Jin-Bao Peng
Summary: A visible-light-induced carbonylation of indoles with phenols has been developed for the synthesis of indole-3-carboxylates, using I-2 as a photosensitive initiator and avoiding the use of transition metal catalysts. Various aryl indole-3-carboxylates were prepared in moderate to good yields, demonstrating the broad applicability of this methodology. Late-stage functionalization of several phenol-containing natural products and pharmaceuticals further highlights the versatility of this approach.
Article
Chemistry, Multidisciplinary
Tim Meyer, Jabor Rabeah, Angelika Brueckner, Xiao-Feng Wu
Summary: The study demonstrated the first transformation using visible light as the oxidant in palladium-catalyzed oxidative carbonylation of amines. The use of a simple Pd complex and mechanistic explanations were supported by control experiments and EPR studies, showing the formation of Pd-I and the active species Pd-0.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Alexander M. Veatch, Shubin Liu, Erik J. Alexanian
Summary: In this study, we demonstrated an aminocarbonylation of aniline-derived trialkylammonium salts promoted by visible light with a simple cobalt catalyst. The reaction proceeds under mild conditions suitable for late-stage functionalization and is amenable to telescoped carbonylations directly from anilines. A range of alkylamines are successful partners, and alkoxycarbonylation is also demonstrated.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Physical
Youcan Zhang, Zhi-Peng Bao, Chang-Sheng Kuai, Xiao-Feng Wu
Summary: Here, we have developed a direct and effective synthesis strategy for sulfur-containing carboxylic acid derivatives through copper/visible light catalyzed ring-opening carbonylation of sulfonium salts. The protocol utilizes photoredox to selectively cleave the C(sp3)-S bond of sulfonium salts, while sequentially functionalizing to form vicinal C-C and C-X (X = O or N) bonds in the presence of carbon monoxide and nucleophiles. Various substrates were successfully transformed into desired carbonylated products with moderate to good yields, displaying good functional group tolerance and excellent chemoselectivity. Importantly, this approach can be easily extended to late-stage modification of bioactive molecules.
JOURNAL OF CATALYSIS
(2023)
Article
Chemistry, Multidisciplinary
Kristian El Chami, Yi Liu, Mohammed A. Belahouane, Yiyang Ma, Pierre-Louis Lagueux-Tremblay, Bruce A. Arndtsen
Summary: In this study, we developed a visible light driven nickel carbonylation catalyst. By combining the Xantphos ligand with nickel(0), we generated a catalyst that can activate alkyl halides for carbonylation reactions at ambient temperature under blue light irradiation, and enable the reductive elimination of high energy acid chloride products. Unlike traditional carbonylations, where the coordination of carbon monoxide inhibits the reactivity of nickel catalysts, we found that a CO-associated nickel is the active catalyst in this reaction. We demonstrated that this catalyst can be used to synthesize various amides, esters, and thioesters, even with sterically encumbered substrates or metal-reactive functionalities.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Shi-Yu Chen, Bai-Hao Ren, Shi-Huan Li, Yu-Hang Song, Shuang Jiao, Chen Zou, Changle Chen, Xiao-Bing Lu, Ye Liu
Summary: Transition-metal-catalyzed copolymerization produces polyketones materials with excellent properties. This study successfully synthesized a series of cationic P,O-coordinated Ni complexes catalysts with outstanding performance, which is a significant discovery in the field of Ni catalysts.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Physical
Yandong Duan, Xuewang Zhu, Qingzhi Luo, Lin Wang, Zhen Li, Desong Wang
Summary: The research successfully fabricated melt-treated AgBr with high photocatalytic activity and stability. By reducing unstable silver ions and surface reconstruction, the stability of AgBr was significantly improved.
JOURNAL OF CATALYSIS
(2021)
Article
Chemistry, Organic
Da-Liang Zhu, Shan Jiang, Qi Wu, Hao Wang, Lu-Lu Chai, Hai-Yan Li, Hong-Xi Li
Summary: A new efficient method has been developed for the photocatalytic P(O)-C(sp(2)) coupling of (hetero)aryl halides with H-phosphine oxides or H-phosphites under visible light or sunlight irradiation, yielding arylphosphine oxides and arylphosphonates. This method is widely tolerant to various functional groups and can proceed efficiently on a gram scale.
Article
Chemistry, Multidisciplinary
Qian Zhang, Jing Hou, Yan Huang, Le-wu Zhan, Bin-dong Li
Summary: A novel method for the synthesis of ureas and formamides using visible-light-induced Ph3P-promoted reactions is reported. Ureas can be directly synthesized at ambient temperature and pressure without external additions. Formamides can be produced by using triisopropylsilanethiol as the hydrogen source.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Physical
Han Yu, Tangyu Zhan, Yuqiao Zhou, Long Chen, Xiaohua Liu, Xiaoming Feng
Summary: Enantioselective photoreduction of ketones with hydrocarbons is a promising method for the synthesis of chiral tertiary alcohols. However, the current approach using ultraviolet light suffers from competitive reactions. In this study, a combined system involving chiral Lewis acid catalysis, photoredox catalysis, and hydrogen atom transfer was developed. The use of a bulky and nonredox chiral Lewis acid in the photoredox pathway successfully promoted the radical addition process and inhibited competitive reactions. Visible-light-promoted catalytic asymmetric alkylation of heteroaryl-based ketones with diverse hydrocarbons resulted in the synthesis of highly congested enantioenriched tertiary alcohols.
Article
Chemistry, Multidisciplinary
Zhiqiang Wei, Zhengzhao Lou, Chuanfa Ni, Wei Zhang, Jinbo Hu
Summary: This study presents a method to achieve S-fluorination of thiophenols using trifluoromethyl phenyl sulfone as a trifluoromethyl radical precursor. The reaction can be conducted under photoredox catalyst-free conditions and enables efficient fluorination of thiophenols.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Organic
Yan-Hua Zhao, Xing-Wei Gu, Xiao-Feng Wu
Summary: This paper reports a ligand-free visible-light-induced manganese-catalyzed carbonylation reaction for the synthesis of various amides. The method offers advantages such as low cost and low toxicity, and can proceed effectively at ambient temperature and pressure.
ORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Multidisciplinary
Qian Wu, Yubo Cui, Guifeng Xia, Jinlong Yang, Shuming Du, Xinhong Xiong, Li Yang, Dong Xu, Xu Deng, Jiaxi Cui
Summary: Passive daytime radiative cooling (PDRC) technology, while promising for global spacing cooling, faces limitations in practical application due to reduced cooling effectiveness caused by wear and dirt contamination. Researchers have developed a renewable armor structure using fluorinated hollow glass microspheres to enhance the anti-fouling and cooling properties of PDRC coatings. The coatings exhibit high solar reflectance and thermal emittance, leading to significant temperature reduction below ambient temperature.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Qiang Bei, Bei Zhang, Kaifeng Wang, Shiming Zhang, Guichuan Xing, Clement Cabanetos
Summary: The power conversion efficiency (PCE) of organic solar cells (OSCs) has reached 20% in recent years, thanks to the advantages of organic photoactive materials. Benzothiadiazole (BT) has attracted significant research attention as a building block of OSCs. OSCs based on BT structure have shown diversity, and the increasing PCE values indicate a promising future for OSCs. This review analyzes the progress made in the last decades, focusing on effective BT small-molecules and BT polymers for OSCs. The structure-property relationships, donor-acceptor matching criteria, and morphology control approaches are discussed. The remaining challenges and a personal perspective on the future advancement of OSCs are summarized.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Rong He, Dandan Tang, Ningge Xu, Heng Liu, Kun Dou, Xuejun Zhou, Fabiao Yu
Summary: Nasopharyngeal carcinoma (NPC) is a common malignant tumor of the head and neck, with a high incidence in China and Southeast Asian countries. In this study, a novel near-infrared fluorescent probe, SNAFL-GSH, was designed and synthesized for the detection of glutathione (GSH). The probe showed selective detection of GSH and the ability to distinguish normal and cancer cells. It has great potential for application in the diagnosis and evaluation of NPC.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Zhukang Guo, Baijiang Jin, Yile Fang, Lian Jin, Song Li, Yan Deng, Zhu Chen, Hui Chen, Yuanying Zhang, Rabia Usman, Nongyue He
Summary: This study isolated primary cells that can be stably passaged from spontaneous tumors of genetically engineered pancreatic ductal adenocarcinoma model mice and used an autonomously developed automated screening instrument for efficient nucleic acid aptamer screening. The obtained aptamers were affinity verified at the cellular level. The study also investigated the impact of cell growth environment difference on the recognition ability of aptamers and confirmed the targeting ability and drug loading ability of the aptamer.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Zhongshan Yang, Qiqi Zhang, Hui Song, Xin Chen, Jiwei Cui, Yanhui Sun, Lequan Liu, Jinhua Ye
Summary: Methane chemistry is a significant area of research in catalysis. Converting methane into value-added chemicals is desirable but challenging due to its high C-H bonding energy and lack of pi bonding or unpaired electrons. Photocatalytic partial oxidation of methane to liquid oxygenates is a promising technology for achieving high efficiency and selectivity under mild conditions. The choice and activation of oxidants are crucial for its performance.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Peng Shan, Jing Liao, Jiayi Li, Chengyan Wang, Jie Zhou, Linqiang Mei, Yunlu Dai, Qiang Wang, Wenyan Yin
Summary: This study reports an oral radioprotectant Gel@GYY that combines a gelatin-based hydrogel and a pH-responsive hydrogen sulfide donor. Gel@GYY has excellent adhesion and sustained release properties, allowing it to release H2S in the gastrointestinal tract and effectively scavenge free radicals induced by radiation. It also reduces inflammation and has biodegradable properties.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lu Liu, Ziyi Liu, Jingnan Cui, Guiling Ning, Weitao Gong
Summary: The development of new metal-free heterogeneous catalysts has been the subject of extensive research. In this study, a new Troger's base (TB)-derived porous organic polymer (POPs) was designed and prepared by integrating multifunctional monomers. The resulting polymer, which combines the advantages of pillar[5]arene macrocycle and TB moiety, exhibited enhanced catalytic performance in Knoevenagel condensation and CO2 conversion, serving as an effective metal-free catalyst. This work provides a new strategy for fabricating metal-free heterogeneous catalysts based on macrocyclic POPs.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Leyong Zhou, Changyin Yang, Weitao Dou, Tongxia Jin, Haibo Yang, Lin Xu
Summary: This review summarizes the application of micro/nanofluidic techniques in constructing supramolecular assemblies of different scales, and highlights the advantages of these techniques over conventional synthesis methods. Furthermore, it emphasizes the potential of micro/nanofluidic systems in improving our understanding of supramolecular self-assembly processes.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Yanchao Jin, Suixiaochen Chen, Peiwen Huang, Xiongjian Chen, Chun-Yan Lin, Li-Ping Li, Xiao Chen, Rui Ding, Jianxi Liu, Riyao Chen
Summary: In this study, magnesium and coconut shell carbon were used to disinfect water by adsorbing copper(II) and converting dissolved oxygen to hydrogen peroxide through Mg corrosion. The copper was enriched on the carbon surface and efficiently catalyzed the hydrogen peroxide to inactivate E.coli. The process showed promising disinfection performance both in laboratory experiments and real wastewater treatment.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Haihong Lai, Zehong Chen, Hao Zhuo, Yijie Hu, Xuan Zhao, Jiwang Yi, Hongzhi Zheng, Ge Shi, Yifan Tong, Ling Meng, Xinwen Peng, Linxin Zhong
Summary: By altering the pyrolysis route of cellulose nanofiber, the structural defects of carbon aerogels can be reduced, leading to improved compressibility and stress retention, as well as higher stress sensor sensitivity and temperature coefficient.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lina Guo, Jinsong Ding, Wenhu Zhou
Summary: Bacteria-based tumor therapy has resurfaced due to the revolution of tumor immunotherapy, offering unique solutions for traditional tumor treatments. Bacteria with active tropism can selectively colonize tumor sites and suppress tumor growth through various mechanisms, making them attractive tools for tumor treatment. This critical review introduces recent advances in bacteria-based tumor therapy, including bacterial properties, their benefits for tumor therapy, anti-tumor mechanisms, challenges, and future perspectives.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lan Liang, Chuanbin Wang, Xukai Lu, Yunan Sun, Beibei Yan, Ning Li, Guanyi Chen, Li'an Hou
Summary: This study investigates the interactions between phenol and benzaldehyde in the ECH process through experiments and theoretical calculations. The results show that phenol can accelerate the conversion of benzaldehyde, while benzaldehyde inhibits the conversion of phenol. The research provides a theoretical basis for the application of ECH in practical bio-oil upgrading.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Pengcheng Fan, Yuhao He, Junan Pan, Ning Sun, Qiyu Zhang, Chen Gu, Kang Chen, Weinan Yin, Longlu Wang
Summary: This study focuses on the recent progress in hydrogen evolution reaction (HER) based on photothermal effect. It introduces the main pathways of photothermal conversions applied in H2 evolution, summarizes the functions of the photothermal effect, and presents a method to improve the catalytic system through thermal means. The study also discusses the challenges and outlook in this promising area.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Leiduo Lai, Hongyu Zhou, Yichen Hong, Mengfan Luo, Yang Shi, Heng Zhang, Zhaokun Xiong, Gang Yao, Bo Lai
Summary: In this study, a facile ammonia reduction strategy was proposed and a novel FeVO3-x catalyst was synthesized for the activation of peroxymonosulfate (PMS) to degrade the pharmaceutical carbamazepine (CBZ). The results showed that the system could rapidly degrade CBZ and generate various active species involved in the degradation process.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Tangxin Xiao, Xiuxiu Li, Liangliang Zhang, Kai Diao, Zheng-Yi Li, Xiao-Qiang Sun, Leyong Wang
Summary: This study presents the construction of a supramolecular light harvesting system based on sequential energy transfer. The system demonstrates tunable fluorescence emission through self-assembly of polymers into nanoparticles, achieving efficient two-step light harvesting.
CHINESE CHEMICAL LETTERS
(2024)