Article
Chemistry, Analytical
Stanislas Nsanzamahoro, Wei-Feng Wang, Ying Zhang, Cheng-Bo Wang, Yves Iradukunda, Yan-Ping Shi, Jun-Li Yang
Summary: The evolution of fluorometric sensing methods has provided a new opportunity for determining enzymatic activities. We have developed a fluorescent sensing approach using silicon nanoparticles that can accurately measure tyrosinase (TYR) activity. This label-free fluorescence turn-on probe showed a selective determination range of TYR activity and was successfully applied to measure TYR activity in human serum samples. Moreover, the biocompatibility and low cytotoxicity of silicon nanoparticles made them suitable for cell imaging applications.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Biochemistry & Molecular Biology
Beste Kapan, Sevinc Kurbanoglu, Emren Nalbant Esenturk, Saniye Soylemez, Levent Toppare
Summary: The study proposed and demonstrated a design for a gold nanoparticle surface used in a nanosensor based on tyrosinase. Through optimization studies, successful immobilization of tyrosinase on a modified electrode was achieved, with catechol as the drug inhibition platform. The sensor showed excellent performance and sensitivity, and was able to detect tyrosinase inhibition and ibuprofen inhibition.
PROCESS BIOCHEMISTRY
(2021)
Article
Biophysics
Shinyoung Choi, Yoon Sung Nam
Summary: This study reports a novel DNA nanoprobe based on plasmon-enhanced fluorescence and quenching effects, which enables rapid, sensitive, and reliable detection of pathogenic DNA.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Chemistry, Physical
Vladimir N. Morozov, Maria A. Kolyvanova, Olga Dement'eva, Victor M. Rudoy, Vladimir A. Kuzmin
Summary: This study investigates the quenching of SYBR Green I and PicoGreen fluorescence by negatively charged 25 nm GNPs in DNA solution and DNA CLCD. The quenching efficiency was dependent on dye concentration and liquid crystalline state, with DNA CLCD showing higher quenching efficacy due to energy transfer.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Analytical
Yuedi Ding, Zhenqiang Fan, Bo Yao, Dong Xu, Minhao Xie, Kai Zhang
Summary: A novel nanoparticle-based fluorescence probe was developed for NF-kappa B transcription factor detection and in situ imaging. The probe utilizes steric hindrance to quench and restore fluorescence signals, achieving a low detection limit and a good linear range.
Article
Biochemical Research Methods
Mehavesh K. Hameed, Javad B. M. Parambath, Sofian M. Kanan, Ahmed A. Mohamed
Summary: Biocompatible and luminescent nanostructures synthesized by capping gold-carbon nanoparticles with amino acids were successfully utilized for the quantitative estimation of the drug ranitidine. The method showed a detection limit of 0.174, 0.56, and 0.332 mu M for different amino acid bioconjugates, and was also successful in quantifying ranitidine in spiked serum samples. The study demonstrates the potential of this approach for sensitive and accurate drug quantification.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Maria Andrea Molina Torres, Alicia Viviana Veglia, Natalia Lorena Pacioni
Summary: The method developed in this study utilizes the fluorescence quenching of rhodamine-6G to quantify gold and silver nanoparticles in aqueous systems. Validation through recovery tests in spiked drinking and surface river water demonstrated the accuracy and reliability of the method, making it a rapid and cost-effective approach for analyzing metal nanoparticles.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Waroton Paisuwan, Mongkol Sukwattanasinitt, Mamoru Tobisu, Anawat Ajavakom
Summary: Novel dihydroquinoline derivatives (DHP and DHP-OH) were synthesized in one-pot by the tandem trimerization-cyclization of methylpropiolate. DHP and DHP-OH exhibited strong blue fluorescence (>0.70 quantum efficiency) in aqueous media. DHP-OH showed remarkable fluorescence quenching selectively to Au3+ through oxidation of dihydropyridine to pyridinium ion, as confirmed by NMR and HRMS. DHP-OH was used for quantitative analysis of Au3+ in water samples (limit of detection: 33 ppb, recovery rate: >95%), as well as for detection of Au3(+) residue in gold nanoparticle solution and on-site detection using a paper-based sensing strip.
Article
Chemistry, Applied
Shijun Lin, Shuwen Liu, Guofei Dai, Xiaojin Zhang, Fan Xia, Yu Dai
Summary: This study presents a click-induced fluorescence-quenching sensor based on gold nanoparticles for rapid detection of copper ions and ascorbic acid. The sensor has a fast response time and high sensitivity, able to detect the concentrations of Cu2+ and AA within less than 3 minutes.
Article
Biochemical Research Methods
Jessy Simon, Sony Udayan, E. S. Bindiya, Sarita G. Bhat, V. P. N. Nampoori, M. Kailasnath
Summary: The interaction between three proteins (BSA, HSA, HEWL) and gold nanoparticles was studied using SPR, fluorescence, CD, TEM, and zeta potential analysis. The stability of protein-GNP complexes was greater than that of individual components, with HEWL-GNP being the most stable. Gold nanoparticles acted as quenchers, reducing protein fluorescence intensity. Absorbance increased with nanoparticle concentration due to peptide strand extension and decreased hydrophobicity.
ANALYTICAL BIOCHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Yaru Huang, Jiefang Yang, Yunyang Chi, Chun Gong, Haikuan Yang, Fanxin Zeng, Fang Gao, Xiaoju Hua, Zongde Wang
Summary: A series of quinazolinone derivates were synthesized as tyrosinase inhibitors and their inhibition constants were evaluated. The compound 2-(2,6-dimethylhepta-1,5-dien-1-yl)quinazolin-4(3H)-one (Q1) was synthesized from natural citral and exhibited significant inhibitory activity. Q1 was identified as a mixed-type and reversible tyrosinase inhibitor. The study also investigated the binding mechanism of Q1 to tyrosinase and found that Q1 could interact with substrates such as tyrosine and L-DOPA.
Article
Chemistry, Multidisciplinary
Guangze Yang, Yun Liu, Yue Hui, Tengjisi, Dong Chen, David A. Weitz, Chun-Xia Zhao
Summary: This study compared two types of dye-labeled nanoparticles and found that nanoparticles with dye molecules in a solid state undergo dye quenching, while those in a soluble state do not. To standardize the comparative study, the proposed solutions include using lower dye loading or utilizing medium analysis for quantifying cell uptake of nanoparticles. Valuable insights into selecting valid quantification methods for bio-nano studies are provided.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Spectroscopy
Anchal Sharma, Harshita Rastogi, Kalyan Sundar Ghosh
Summary: The chaperone activity of human alpha A-crystallin (HAA) against aggregation of human gamma D-crystallin (HGD) was enhanced by gold nanoparticles (AuNPs), and the interactions between HAA and AuNPs were studied using fluorescence and circular dichroism spectroscopic techniques.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Inorganic & Nuclear
D. Bharathi, B. Siddlingeshwar, R. Hari Krishna, Elena M. Kirilova, Darshan Devang Divakar, Abdulaziz Abdullah Alkheraif
Summary: This study investigates the interaction of the fluorescent probe 3-MAB with copper oxide and zinc oxide nanoparticles, revealing insights through absorption and fluorescence techniques. Through steady state fluorescence quenching experiments in different solvents, the binding constant, bimolecular quenching rate constant, and binding sites were determined.
INORGANIC CHEMISTRY COMMUNICATIONS
(2021)
Article
Biochemical Research Methods
Mengmeng Liu, Fei Wang, Xueli Zhang, Xiuhai Mao, Lihua Wang, Yang Tian, Chunhai Fan, Qian Li
Summary: This method provides a step-by-step correlative imaging approach to investigate plasmonic NPs of different aggregation states in single cells. By using dark-field microscopy, fluorescence microscopy, and scanning electron microscopy, the clustering states of SNAs in a single cell can be efficiently distinguished and tracked in real time within 20 seconds. The entire procedure can be completed in 3-5 days and requires standard imaging and data analysis skills and equipment.
Review
Nanoscience & Nanotechnology
Qin Hu, Xiaojuan Gong, Lizhen Liu, Martin M. F. Choi
JOURNAL OF NANOMATERIALS
(2017)
Article
Environmental Sciences
Ke Chen, Qing Zhu, Yiguang Qian, Ying Song, Jun Yao, Martin M. F. Choi
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2013)
Article
Electrochemistry
Ying Huang, Changming Cheng, Xianqing Tian, Baozhan Zheng, Yi Li, Hongyan Yuan, Dan Xiao, Martin M. F. Choi
ELECTROCHIMICA ACTA
(2013)
Article
Engineering, Chemical
Guangming Wen, Zhongping Li, Martin M. F. Choi
JOURNAL OF FOOD ENGINEERING
(2013)
Article
Chemistry, Organic
Qiaoling Liu, Wei Bian, Heping Shi, Li Fan, Shaomin Shuang, Chuan Dong, Martin M. F. Choi
ORGANIC & BIOMOLECULAR CHEMISTRY
(2013)
Article
Biochemical Research Methods
Ting Wan, Fenglin Tang, Yanru Yin, Maoxue Zhang, Martin M. F. Choi, Xiupei Yang
Article
Nanoscience & Nanotechnology
Xiupei Yang, Zhengli Yang, Fenglin Tang, Jing Xu, Maoxue Zhang, Martin M. F. Choi
BEILSTEIN JOURNAL OF NANOTECHNOLOGY
(2019)
Article
Chemistry, Physical
Chaofan Chai, Xiaohong Qiao, Lingling Zheng, Hubin Duan, Wei Bian, Martin M. F. Choi
Summary: PHBA, a main ingredient in the traditional Chinese medicine Gastrodia elata, has various pharmacological effects, making monitoring its levels significant for evaluating its pharmacokinetics and toxic effects. Nitrogen-doped carbon dots (NCDs) were designed for the sensitive detection of PHBA, showing success in detecting PHBA in blood and urine samples.
FULLERENES NANOTUBES AND CARBON NANOSTRUCTURES
(2022)
Article
Materials Science, Multidisciplinary
Chaofan Chai, Xuefang Yang, Xiaohua Yang, Chuan Dong, Wei Bian, Martin M. F. Choi
Summary: A MnO2-S, O-CNQDs nanoprobe was developed for rapid detection of trace amounts of GSH, showing potential biomedical applications and low biotoxicity. The non-fluorescence MnO2-S, O-CNQDs reacted with GSH to recover fluorescence, offering a useful tool for monitoring GSH in cancer cells.
JOURNAL OF MATERIALS SCIENCE
(2022)
Article
Chemistry, Analytical
Mengting Zhang, Yulu Zhang, Mingyu Gan, Liping Xie, Jing Wang, Weihua Jia, Wei Bian, Shaomin Shuang, Martin M. F. Choi
Summary: In this study, fluorescent sulfur and oxygen co-doped graphitic carbon nitride quantum dots (S,O-CNQDs) were prepared and utilized as a probe for the detection of Cu2+. The S,O-CNQDs exhibited efficient fluorescence quenching by Cu2+ under optimum conditions, enabling their application in various samples such as tap water, lake water, human serum, urine, and living cells. The as-prepared S,O-CNQDs showed excellent properties and have potential for biological applications.
METHODS AND APPLICATIONS IN FLUORESCENCE
(2022)
Article
Chemistry, Analytical
Lingling Zheng, Yangyang Yan, Ning Wang, Mingli Li, Shaomin Shuang, Wei Bian, Martin M. F. Choi
Summary: Silver is widely used as a precious metal in various industries, but its large-scale production and waste emissions contribute to environmental pollution. Efficient and sensitive detection of silver ions (Ag+) in the water environment is crucial. This study successfully detected Ag+ in different environmental water samples and cells using sulfur-doped carbon nitride nanosheets (SCN Ns) as a fluorescent probe.
METHODS AND APPLICATIONS IN FLUORESCENCE
(2022)
Article
Chemistry, Analytical
Xiaohua Yang, Peigang Zhang, Jie Tan, Xuebing Li, Weidong Zhang, Wei Bian, Martin M. F. Choi
Summary: Graphene quantum dots (GQDs) with excellent stability, biocompatibility, and photoluminescence property have been attracting growing attention in the field of metal ions detection. Glutathione (GSH) functionalized boron doped graphene quantum dots (B-GQDs@GSH) were successfully synthesized, which showed stable bright blue fluorescence and were used for the detection of Fe3+. The application of B-GQDs@GSH for Fe3+ detection in water samples and their use in cell fluorescence imaging and intracellular determination of Fe3+ were demonstrated.
JOURNAL OF ANALYSIS AND TESTING
(2023)
Article
Materials Science, Multidisciplinary
Xiaohua Yang, Wenjing He, Mingyu Gan, Shaomin Shuang, Martin M. F. Choi, Wei Bian
Summary: In this study, a dual response ratiometric fluorescent probe was constructed for the rapid, on-site, sensitive, and selective detection of tetracycline (TC). The probe was synthesized by mixing sodium citrate (CitNa), europium ion (Eu3+), and sulfur and oxygen co-doped graphite phase carbon nitride quantum dots (S,O-C(3)N(4)QDs) solution in a specific proportion. The probe exhibited a significant decrease in blue fluorescence (lambda(em) = 445 nm) and an increase in red fluorescence (lambda(em) = 620 nm) in the presence of TC, allowing for ultra-sensitive detection from 0.25 to 120 μM, with a detection limit of 1.3 nM. A smartphone app monitoring platform based on test paper was also developed, demonstrating the potential application of the ratiometric fluorescent probe in medical and environmental fields.
JOURNAL OF MATERIALS SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Shuyun Guo, Lingling Zheng, Wenjing He, Chaofan Chai, Xianghui Chen, Shaofang Ma, Ning Wang, Martin M. F. Choi, Wei Bian
Summary: A novel nanoprobe based on S,O-doped carbon nitride quantum dots was synthesized and demonstrated for the detection of folic acid (FA). The nanoprobe showed good biocompatibility and strong fluorescence at 360 nm excitation. It exhibited high sensitivity and selectivity towards FA in the concentration range of 5.0-83.3 μM, with a detection limit of 90 nM. The nanoprobe was successfully applied for FA detection in real samples with satisfactory recoveries and low relative standard deviation. The FA-S,O-CNQDs formed through a classical cross-linking reaction showed great potential in FA detection and targeted imaging of cancer cells.
ARABIAN JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Analytical
Lei Zhang, Qin Hu, Zhongping Li, Yan Zhang, Dongtao Lu, Shaomin Shuang, Martin M. F. Choi, Chuan Dong
ANALYTICAL METHODS
(2017)
Article
Chemistry, Multidisciplinary
Qian Wu, Yubo Cui, Guifeng Xia, Jinlong Yang, Shuming Du, Xinhong Xiong, Li Yang, Dong Xu, Xu Deng, Jiaxi Cui
Summary: Passive daytime radiative cooling (PDRC) technology, while promising for global spacing cooling, faces limitations in practical application due to reduced cooling effectiveness caused by wear and dirt contamination. Researchers have developed a renewable armor structure using fluorinated hollow glass microspheres to enhance the anti-fouling and cooling properties of PDRC coatings. The coatings exhibit high solar reflectance and thermal emittance, leading to significant temperature reduction below ambient temperature.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Qiang Bei, Bei Zhang, Kaifeng Wang, Shiming Zhang, Guichuan Xing, Clement Cabanetos
Summary: The power conversion efficiency (PCE) of organic solar cells (OSCs) has reached 20% in recent years, thanks to the advantages of organic photoactive materials. Benzothiadiazole (BT) has attracted significant research attention as a building block of OSCs. OSCs based on BT structure have shown diversity, and the increasing PCE values indicate a promising future for OSCs. This review analyzes the progress made in the last decades, focusing on effective BT small-molecules and BT polymers for OSCs. The structure-property relationships, donor-acceptor matching criteria, and morphology control approaches are discussed. The remaining challenges and a personal perspective on the future advancement of OSCs are summarized.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Rong He, Dandan Tang, Ningge Xu, Heng Liu, Kun Dou, Xuejun Zhou, Fabiao Yu
Summary: Nasopharyngeal carcinoma (NPC) is a common malignant tumor of the head and neck, with a high incidence in China and Southeast Asian countries. In this study, a novel near-infrared fluorescent probe, SNAFL-GSH, was designed and synthesized for the detection of glutathione (GSH). The probe showed selective detection of GSH and the ability to distinguish normal and cancer cells. It has great potential for application in the diagnosis and evaluation of NPC.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Zhukang Guo, Baijiang Jin, Yile Fang, Lian Jin, Song Li, Yan Deng, Zhu Chen, Hui Chen, Yuanying Zhang, Rabia Usman, Nongyue He
Summary: This study isolated primary cells that can be stably passaged from spontaneous tumors of genetically engineered pancreatic ductal adenocarcinoma model mice and used an autonomously developed automated screening instrument for efficient nucleic acid aptamer screening. The obtained aptamers were affinity verified at the cellular level. The study also investigated the impact of cell growth environment difference on the recognition ability of aptamers and confirmed the targeting ability and drug loading ability of the aptamer.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Zhongshan Yang, Qiqi Zhang, Hui Song, Xin Chen, Jiwei Cui, Yanhui Sun, Lequan Liu, Jinhua Ye
Summary: Methane chemistry is a significant area of research in catalysis. Converting methane into value-added chemicals is desirable but challenging due to its high C-H bonding energy and lack of pi bonding or unpaired electrons. Photocatalytic partial oxidation of methane to liquid oxygenates is a promising technology for achieving high efficiency and selectivity under mild conditions. The choice and activation of oxidants are crucial for its performance.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Peng Shan, Jing Liao, Jiayi Li, Chengyan Wang, Jie Zhou, Linqiang Mei, Yunlu Dai, Qiang Wang, Wenyan Yin
Summary: This study reports an oral radioprotectant Gel@GYY that combines a gelatin-based hydrogel and a pH-responsive hydrogen sulfide donor. Gel@GYY has excellent adhesion and sustained release properties, allowing it to release H2S in the gastrointestinal tract and effectively scavenge free radicals induced by radiation. It also reduces inflammation and has biodegradable properties.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lu Liu, Ziyi Liu, Jingnan Cui, Guiling Ning, Weitao Gong
Summary: The development of new metal-free heterogeneous catalysts has been the subject of extensive research. In this study, a new Troger's base (TB)-derived porous organic polymer (POPs) was designed and prepared by integrating multifunctional monomers. The resulting polymer, which combines the advantages of pillar[5]arene macrocycle and TB moiety, exhibited enhanced catalytic performance in Knoevenagel condensation and CO2 conversion, serving as an effective metal-free catalyst. This work provides a new strategy for fabricating metal-free heterogeneous catalysts based on macrocyclic POPs.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Leyong Zhou, Changyin Yang, Weitao Dou, Tongxia Jin, Haibo Yang, Lin Xu
Summary: This review summarizes the application of micro/nanofluidic techniques in constructing supramolecular assemblies of different scales, and highlights the advantages of these techniques over conventional synthesis methods. Furthermore, it emphasizes the potential of micro/nanofluidic systems in improving our understanding of supramolecular self-assembly processes.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Yanchao Jin, Suixiaochen Chen, Peiwen Huang, Xiongjian Chen, Chun-Yan Lin, Li-Ping Li, Xiao Chen, Rui Ding, Jianxi Liu, Riyao Chen
Summary: In this study, magnesium and coconut shell carbon were used to disinfect water by adsorbing copper(II) and converting dissolved oxygen to hydrogen peroxide through Mg corrosion. The copper was enriched on the carbon surface and efficiently catalyzed the hydrogen peroxide to inactivate E.coli. The process showed promising disinfection performance both in laboratory experiments and real wastewater treatment.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Haihong Lai, Zehong Chen, Hao Zhuo, Yijie Hu, Xuan Zhao, Jiwang Yi, Hongzhi Zheng, Ge Shi, Yifan Tong, Ling Meng, Xinwen Peng, Linxin Zhong
Summary: By altering the pyrolysis route of cellulose nanofiber, the structural defects of carbon aerogels can be reduced, leading to improved compressibility and stress retention, as well as higher stress sensor sensitivity and temperature coefficient.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lina Guo, Jinsong Ding, Wenhu Zhou
Summary: Bacteria-based tumor therapy has resurfaced due to the revolution of tumor immunotherapy, offering unique solutions for traditional tumor treatments. Bacteria with active tropism can selectively colonize tumor sites and suppress tumor growth through various mechanisms, making them attractive tools for tumor treatment. This critical review introduces recent advances in bacteria-based tumor therapy, including bacterial properties, their benefits for tumor therapy, anti-tumor mechanisms, challenges, and future perspectives.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lan Liang, Chuanbin Wang, Xukai Lu, Yunan Sun, Beibei Yan, Ning Li, Guanyi Chen, Li'an Hou
Summary: This study investigates the interactions between phenol and benzaldehyde in the ECH process through experiments and theoretical calculations. The results show that phenol can accelerate the conversion of benzaldehyde, while benzaldehyde inhibits the conversion of phenol. The research provides a theoretical basis for the application of ECH in practical bio-oil upgrading.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Pengcheng Fan, Yuhao He, Junan Pan, Ning Sun, Qiyu Zhang, Chen Gu, Kang Chen, Weinan Yin, Longlu Wang
Summary: This study focuses on the recent progress in hydrogen evolution reaction (HER) based on photothermal effect. It introduces the main pathways of photothermal conversions applied in H2 evolution, summarizes the functions of the photothermal effect, and presents a method to improve the catalytic system through thermal means. The study also discusses the challenges and outlook in this promising area.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Leiduo Lai, Hongyu Zhou, Yichen Hong, Mengfan Luo, Yang Shi, Heng Zhang, Zhaokun Xiong, Gang Yao, Bo Lai
Summary: In this study, a facile ammonia reduction strategy was proposed and a novel FeVO3-x catalyst was synthesized for the activation of peroxymonosulfate (PMS) to degrade the pharmaceutical carbamazepine (CBZ). The results showed that the system could rapidly degrade CBZ and generate various active species involved in the degradation process.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Tangxin Xiao, Xiuxiu Li, Liangliang Zhang, Kai Diao, Zheng-Yi Li, Xiao-Qiang Sun, Leyong Wang
Summary: This study presents the construction of a supramolecular light harvesting system based on sequential energy transfer. The system demonstrates tunable fluorescence emission through self-assembly of polymers into nanoparticles, achieving efficient two-step light harvesting.
CHINESE CHEMICAL LETTERS
(2024)